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496100 Omeprazole - CAS 73590-58-6 - Calbiochem

A cell-permeable pyridyl methylsulfinyl benzimidazole compound that acts as selective proton pump inhibitor.

Omeprazole - CAS 73590-58-6 - Calbiochem: Ficha de datos de seguridad (MSDS o SDS), certificado de análisis y de calidad (CoA y CoQ), expedientes, folletos y otros documentos disponibles.

Sinónimos: H 168/68, 5-Methoxy-2[(4-methoxy-3,5-dimethyl-2-pyridyl)methylsulfinyl]-1H-benzimidazole

Primary Target: proton pump
496100
Purchase on Sigma-Aldrich

Descripción

Replacement Information

Tabla espec. clave

CAS #Empirical Formula
73590-58-6C₁₇H₁₉N₃O₃S

Products

Número de referenciaEmbalaje Cant./Env.
496100-50MG Ampolla de plást. 50 mg
Description
OverviewA cell-permeable pyridyl methylsulfinyl benzimidazole compound that acts as selective proton pump inhibitor. Behaves as a prodrug by undergoing an acid-catalyzed rearrangement to a thiol-reactive cationic sulfenamide that inhibits (H+, K+)-ATPase in the gastric milieu. An aryl hydrocarbon-like inducer of cytochrome P450 secretion in human liver.
Catalogue Number496100
Brand Family Calbiochem®
SynonymsH 168/68, 5-Methoxy-2[(4-methoxy-3,5-dimethyl-2-pyridyl)methylsulfinyl]-1H-benzimidazole
References
ReferencesLambrecht, N., et al. 2000. J. Biol. Chem. 275, 4041.
Besancon, M., et al. 1997. J. Biol. Chem. 272, 22438.
Sachs, G., et al. 1995. Ann. Rev. Pharmacol. Toxicol. 35, 277.
Diaz, D., et al. 1990. Gastroenterology 99, 737.
Fellenius, E., et al. 1981. Nature 290, 159.
Product Information
CAS number73590-58-6
ATP CompetitiveN
FormTan to off-white solid
Hill FormulaC₁₇H₁₉N₃O₃S
Chemical formulaC₁₇H₁₉N₃O₃S
ReversibleN
Structure formula ImageStructure formula Image
Quality LevelMQ100
Applications
Biological Information
Primary Targetproton pump
Purity≥94% by HPLC
Physicochemical Information
Cell permeableY
ContaminantsHeavy metals: ≤20 ppm
Dimensions
Materials Information
Toxicological Information
Safety Information according to GHS
RTECSDD9087000
Safety Information
R PhraseR: 36/37/38

Irritating to eyes, respiratory system and skin.
S PhraseS: 26-36

In case of contact with eyes, rinse immediately with plenty of water and seek medical advice.
Wear suitable protective clothing.
Product Usage Statements
Storage and Shipping Information
Ship Code Ambient Temperature Only
Toxicity Irritant
Storage +2°C to +8°C
Protect from Light Protect from light
Do not freeze Ok to freeze
Special InstructionsFollowing reconstitution, aliquot and freeze (-20°C). Stock solutions are stable for up to 3 months at -20°C.
Packaging Information
Packaged under inert gas Packaged under inert gas
Transport Information
Supplemental Information
Specifications
Global Trade Item Number
Número de referencia GTIN
496100-50MG 04055977199833

Documentation

Omeprazole - CAS 73590-58-6 - Calbiochem Ficha datos de seguridad (MSDS)

Título

Ficha técnica de seguridad del material (MSDS) 

Omeprazole - CAS 73590-58-6 - Calbiochem Certificados de análisis

CargoNúmero de lote
496100

Referencias bibliográficas

Visión general referencias
Lambrecht, N., et al. 2000. J. Biol. Chem. 275, 4041.
Besancon, M., et al. 1997. J. Biol. Chem. 272, 22438.
Sachs, G., et al. 1995. Ann. Rev. Pharmacol. Toxicol. 35, 277.
Diaz, D., et al. 1990. Gastroenterology 99, 737.
Fellenius, E., et al. 1981. Nature 290, 159.
Ficha técnica

Note that this data sheet is not lot-specific and is representative of the current specifications for this product. Please consult the vial label and the certificate of analysis for information on specific lots. Also note that shipping conditions may differ from storage conditions.

Revision13-March-2013 JSW
SynonymsH 168/68, 5-Methoxy-2[(4-methoxy-3,5-dimethyl-2-pyridyl)methylsulfinyl]-1H-benzimidazole
DescriptionA cell-permeable, selective proton pump inhibitor. Behaves as a prodrug by undergoing an acid-catalyzed rearrangement to a thiol-reactive cationic sulfenamide that inhibits (H+-K+)-ATPase in the gastric milieu. Also acts as an aryl hydrocarbon-like inducer of cytochrome P450 secretion in human liver.
FormTan to off-white solid
Intert gas (Yes/No) Packaged under inert gas
CAS number73590-58-6
RTECSDD9087000
Chemical formulaC₁₇H₁₉N₃O₃S
Structure formulaStructure formula
Purity≥94% by HPLC
ContaminantsHeavy metals: ≤20 ppm
SolubilityDMSO (25 mg/ml)
Storage Protect from light
+2°C to +8°C
Do Not Freeze Ok to freeze
Special InstructionsFollowing reconstitution, aliquot and freeze (-20°C). Stock solutions are stable for up to 3 months at -20°C.
Toxicity Irritant
Merck USA index14, 6845
ReferencesLambrecht, N., et al. 2000. J. Biol. Chem. 275, 4041.
Besancon, M., et al. 1997. J. Biol. Chem. 272, 22438.
Sachs, G., et al. 1995. Ann. Rev. Pharmacol. Toxicol. 35, 277.
Diaz, D., et al. 1990. Gastroenterology 99, 737.
Fellenius, E., et al. 1981. Nature 290, 159.