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GF308 NT-3 Protein, Human Recombinant Animal Free

Recombinant animal free human NT-3 is manufactured using all non-animal reagents.

NT-3 Protein, Human Recombinant Animal Free: Ficha de datos de seguridad (MSDS o SDS), certificado de análisis y de calidad (CoA y CoQ), expedientes, folletos y otros documentos disponibles.
UniProt Number: P20783
GF308
10 µg  
Purchase on Sigma-Aldrich

Descripción

Tabla espec. clave

SourcePurity
E. coli Product is endotoxin free (< 0.1ng/μg of protein (<1EU/μg) and greater than 98% pure by SDS-PAGE gel and HPLC analyses
Description
Catalogue NumberGF308
DescriptionNT-3 Protein, Human Recombinant Animal Free
Alternate Names
  • NT3
  • Neurotrophin 3
  • HDNF
  • Nerve growth factor 2
  • Neurotrophic factor
Background InformationNeurotrophin3 (NT3) is a member of the NGF family of neurotrophic factors (also named neurotrophins) that are required for the differentiation and survival of specific neuronal subpopulations in both the central as well as the peripheral nervous systems. The neurotrophin family is comprised of at least four proteins including NGF, BDNF, NT3, and NT4/5. NT-3 is expressed by neurons of the central nervous systems and can signal through the trk receptors. NT-3 promotes the growth and survival of nerve and glial cells. The amino acid sequences of human, murine and rat NT-3 are identical. Recombinant human NT-3 is a noncovalently linked homodimer, of two 13.6 kDa polypeptide monomers (240 total amino acid residues).Human and Mouse NT-3 sequences are identical.
Product Information
Formulation
PresentationProduct is filtered through a 0.2 micron filter before lyophilization. Product is presented in .
Quality LevelMQ100
Applications
ApplicationRecombinant animal free human NT-3 is manufactured using all non-animal reagents.
Biological Information
PurityProduct is endotoxin free (< 0.1ng/μg of protein (<1EU/μg) and greater than 98% pure by SDS-PAGE gel and HPLC analyses
SourceE. coli
Cross ReactivityNone
UniProt Number
Product Usage Statements
Quality AssuranceBioactivity assay: The ED50 as determined by the dose-dependent induction of choline acetyl transferase activity in rat basal forebrain primary septal cell cultures was found in the range of 20-50 ng/ml.
Usage Statement
  • Unless otherwise stated in our catalog or other company documentation accompanying the product(s), our products are intended for research use only and are not to be used for any other purpose, which includes but is not limited to, unauthorized commercial uses, in vitro diagnostic uses, ex vivo or in vivo therapeutic uses or any type of consumption or application to humans or animals.
Storage and Shipping Information
Storage ConditionsStore at -20°C for up to 6 months from date of receipt.
Packaging Information
Material Size10 µg
Global Trade Item Number
Número de referencia GTIN
GF308 04053252691317