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444264 MMP Inhibitor III - CAS 927827-98-3 - Calbiochem

The MMP Inhibitor III, also referenced under CAS 927827-98-3, controls the biological activity of MMP. This small molecule/inhibitor is primarily used for Protease Inhibitors applications.

Ficha de datos de seguridad (MSDS o SDS), certificado de análisis y de calidad (CoA y CoQ), expedientes, folletos y otros documentos disponibles.
Primary Target: MMP-1
444264
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Descripción

Replacement Information

Tabla espec. clave

CAS #Empirical Formula
927827-98-3C₁₉H₂₉N₃O₄

Products

Número de referenciaEmbalaje Cant./Env.
444264-1MG Ampolla de plást. 1 mg
Description
OverviewA homophenylalanine-hydroxamic acid based broad-spectrum cell-permeable, reversible inhibitor of matrix metalloproteinases (supplied as a racemic mixture). Inhibits MMP-1 (IC50 = 7.4 nM), MMP-2 (IC50 = 2.3 nM), MMP-3 (IC50 = 135 nM), MMP-7 (IC50 = 10-100 nM), and MMP-13 (IC50 = 1-10 nM).
Catalogue Number444264
Brand Family Calbiochem®
References
ReferencesCovington, M.D., et al. 2006, Am. J. Physiol. Renal. Physiol. 290, F43.
Product Information
CAS number927827-98-3
ATP CompetitiveN
FormOff-white lyophilized solid
Hill FormulaC₁₉H₂₉N₃O₄
Chemical formulaC₁₉H₂₉N₃O₄
ReversibleY
Structure formula ImageStructure formula Image
Quality LevelMQ100
Applications
Biological Information
Primary TargetMMP-1
Primary Target IC<sub>50</sub>7.4 nM, 2.3 nM, 135 nM, 10-100 nM, 1-10 nM, against MMP-1, MMP-2, MMP-3, MMP-7, and MMP-13, respectively
Purity≥90% by TLC
Physicochemical Information
Cell permeableY
Dimensions
Materials Information
Toxicological Information
Safety Information according to GHS
Safety Information
Product Usage Statements
Storage and Shipping Information
Ship Code Ambient Temperature Only
Toxicity Standard Handling
Storage -20°C
Protect from Moisture Protect from moisture
Do not freeze Ok to freeze
Special InstructionsFollowing reconstitution, aliquot and freeze (-20°C). Stock solutions are stable for up to 6 months (-20°C).
Packaging Information
Transport Information
Supplemental Information
Specifications
Global Trade Item Number
Número de referencia GTIN
444264-1MG 07790788050382

Documentation

MMP Inhibitor III - CAS 927827-98-3 - Calbiochem Ficha datos de seguridad (MSDS)

Título

Ficha técnica de seguridad del material (MSDS) 

MMP Inhibitor III - CAS 927827-98-3 - Calbiochem Certificados de análisis

CargoNúmero de lote
444264

Referencias bibliográficas

Visión general referencias
Covington, M.D., et al. 2006, Am. J. Physiol. Renal. Physiol. 290, F43.

Citas

Título
  • Haili Su, et al. (2005) Noninvasive targeted imaging of matrix metalloproteinase activation in a murine model of postinfarction remodeling. Circulation 112, 3157-3167.
    		•
    Ficha técnica

    Note that this data sheet is not lot-specific and is representative of the current specifications for this product. Please consult the vial label and the certificate of analysis for information on specific lots. Also note that shipping conditions may differ from storage conditions.

    Revision07-June-2015 JSW
    DescriptionA homophenylalanine-hydroxamic acid based broad-spectrum cell-permeable, reversible inhibitor of matrix metalloproteinases (supplied as a racemic mixture). Inhibits MMP-1 (IC50 = 7.4 nM), MMP-2 (IC50 = 2.3 nM), MMP-3 (IC50 = 135 nM), MMP-7 (IC50 = 10-100 nM), and MMP-13 (IC50 = 1-10 nM).
    FormOff-white lyophilized solid
    CAS number927827-98-3
    Chemical formulaC₁₉H₂₉N₃O₄
    Structure formulaStructure formula
    Purity≥90% by TLC
    SolubilityDMSO (5 mg/ml)
    Storage Protect from moisture
    -20°C
    Do Not Freeze Ok to freeze
    Special InstructionsFollowing reconstitution, aliquot and freeze (-20°C). Stock solutions are stable for up to 6 months (-20°C).
    Toxicity Standard Handling
    ReferencesCovington, M.D., et al. 2006, Am. J. Physiol. Renal. Physiol. 290, F43.
    Citation
  • Haili Su, et al. (2005) Noninvasive targeted imaging of matrix metalloproteinase activation in a murine model of postinfarction remodeling. Circulation 112, 3157-3167.
    		•