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444278 MMP-9 Inhibitor I - CAS 1177749-58-4 - Calbiochem

MMP-9 Inhibitor I, CAS 1177749-58-4, is a cell-permeable, potent, and reversible MMP-9 Inhibitor (IC₅₀ = 5 nM). At high concentration inhibits MMP-1 (IC₅₀ = 1.05 µM) & MMP-13 (IC₅₀ = 113 nM).

Ficha de datos de seguridad (MSDS o SDS), certificado de análisis y de calidad (CoA y CoQ), expedientes, folletos y otros documentos disponibles.
Primary Target: MMP-9
444278
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Descripción

Replacement Information

Tabla espec. clave

CAS #Empirical Formula
1177749-58-4C₂₇H₃₃N₃O₅S

Products

Número de referenciaEmbalaje Cant./Env.
444278-500UG Ampolla de plást. 500 μg
Description
OverviewA cell-permeable, potent, selective, and reversible MMP-9 Inhibitor (IC50 = 5 nM). Inhibits MMP-1 (IC50 = 1.05 µM) and MMP-13 (IC50 = 113 nM) only at much higher concentrations.
Catalogue Number444278
Brand Family Calbiochem®
References
ReferencesLevin, J.I., et al. 2001. Bioorg. Med. Chem. Lett. 11, 2189.
Product Information
CAS number1177749-58-4
ATP CompetitiveN
FormOff-white solid
Hill FormulaC₂₇H₃₃N₃O₅S
Chemical formulaC₂₇H₃₃N₃O₅S
ReversibleY
Structure formula ImageStructure formula Image
Quality LevelMQ100
Applications
Biological Information
Primary TargetMMP-9
Primary Target IC<sub>50</sub>5 nM
Purity≥93% by HPLC
Physicochemical Information
Cell permeableY
Dimensions
Materials Information
Toxicological Information
Safety Information according to GHS
Safety Information
Product Usage Statements
Storage and Shipping Information
Ship Code Ambient Temperature Only
Toxicity Standard Handling
Storage -20°C
Protect from Light Protect from light
Do not freeze Ok to freeze
Special InstructionsFollowing reconstitution aliquot and freeze (-20°C). Stock solutions are stable for up to 6 months at -20°C.
Packaging Information
Packaged under inert gas Packaged under inert gas
Transport Information
Supplemental Information
Specifications
Global Trade Item Number
Número de referencia GTIN
444278-500UG 04055977186598

Documentation

MMP-9 Inhibitor I - CAS 1177749-58-4 - Calbiochem Ficha datos de seguridad (MSDS)

Título

Ficha técnica de seguridad del material (MSDS) 

MMP-9 Inhibitor I - CAS 1177749-58-4 - Calbiochem Certificados de análisis

CargoNúmero de lote
444278

Referencias bibliográficas

Visión general referencias
Levin, J.I., et al. 2001. Bioorg. Med. Chem. Lett. 11, 2189.

Citas

Título
  • White A.R, et al. 2006. journal of Biological Chemistry 281, 17670.
  • Michelle K.Y. Siu and C. Yan Cheng. 2004. Biology of Reproduction 70, 945.
  • Lubbe, WL, et al. 2006. Clin. Cancer Res. 12 1876.
    		•
    Ficha técnica

    Note that this data sheet is not lot-specific and is representative of the current specifications for this product. Please consult the vial label and the certificate of analysis for information on specific lots. Also note that shipping conditions may differ from storage conditions.

    Revision13-April-2011 RFH
    DescriptionA cell-permeable, potent, selective, and reversible inhibitor of MMP-9 (IC50 = 5 nM). Also inhibits MMP-1 (IC50 = 1.05 µM) and MMP-13 IC50 = 113 nM) at higher concentrations.
    FormOff-white solid
    Intert gas (Yes/No) Packaged under inert gas
    CAS number1177749-58-4
    Chemical formulaC₂₇H₃₃N₃O₅S
    Structure formulaStructure formula
    Purity≥93% by HPLC
    SolubilityDMSO (10 mg/ml)
    Storage Protect from light
    -20°C
    Do Not Freeze Ok to freeze
    Special InstructionsFollowing reconstitution aliquot and freeze (-20°C). Stock solutions are stable for up to 6 months at -20°C.
    Toxicity Standard Handling
    ReferencesLevin, J.I., et al. 2001. Bioorg. Med. Chem. Lett. 11, 2189.
    Citation
  • White A.R, et al. 2006. journal of Biological Chemistry 281, 17670.
  • Michelle K.Y. Siu and C. Yan Cheng. 2004. Biology of Reproduction 70, 945.
  • Lubbe, WL, et al. 2006. Clin. Cancer Res. 12 1876.
    		•