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444286 MMP-2 Inhibitor II - CAS 869577-51-5 - Calbiochem

The MMP-2 Inhibitor II, also referenced under CAS 869577-51-5, controls the biological activity of MMP-2. This small molecule/inhibitor is primarily used for Protease Inhibitors applications.

Ficha de datos de seguridad (MSDS o SDS), certificado de análisis y de calidad (CoA y CoQ), expedientes, folletos y otros documentos disponibles.

Sinónimos: (4-(4-(Methanesulfonamido)phenoxy)phenylsulfonyl)methyloxirane

Primary Target: MMP-2
444286
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Descripción

Replacement Information

Tabla espec. clave

CAS #Empirical Formula
869577-51-5C₁₆H₁₇NO₆S₂

Products

Número de referenciaEmbalaje Cant./Env.
444286-5MG Ampolla de plást. 5 mg
Description
OverviewAn oxirane analog of SB-3CT, pMS (Cat. No. 444285) that acts as a selective, active site-binding, irreversible inhibitor of MMP-2 (Ki = 2.4 µM). Although less potent, it exhibits enhanced selectivity towards MMP-2 (Ki = 45 and 379 µM for MMP-1 and MMP-7, respectively) than SB-3CT, pMS.
Catalogue Number444286
Brand Family Calbiochem®
Synonyms(4-(4-(Methanesulfonamido)phenoxy)phenylsulfonyl)methyloxirane
References
ReferencesIkejiri, M., et al. 2005. J. Biol. Chem. 280, 33992.
Product Information
CAS number869577-51-5
FormWhite solid
Hill FormulaC₁₆H₁₇NO₆S₂
Chemical formulaC₁₆H₁₇NO₆S₂
ReversibleN
Structure formula ImageStructure formula Image
Quality LevelMQ100
Applications
Biological Information
Primary TargetMMP-2
Primary Target K<sub>i</sub>2.4 µM
Secondary targetMMP-2 (Ki = 45 and 379 µM for MMP-1 and MMP-7, respectively)
Purity≥97% by HPLC
Physicochemical Information
Dimensions
Materials Information
Toxicological Information
Safety Information according to GHS
Safety Information
Product Usage Statements
Storage and Shipping Information
Ship Code Ambient Temperature Only
Toxicity Standard Handling
Storage -20°C
Protect from Light Protect from light
Protect from Moisture Protect from moisture
Do not freeze Ok to freeze
Special InstructionsFollowing reconstitution, aliquot and freeze (-20°C). Stock solutions are stable for up to 1 month at -20°C.
Packaging Information
Packaged under inert gas Packaged under inert gas
Transport Information
Supplemental Information
Specifications
Global Trade Item Number
Número de referencia GTIN
444286-5MG 04055977186031

Documentation

MMP-2 Inhibitor II - CAS 869577-51-5 - Calbiochem Ficha datos de seguridad (MSDS)

Título

Ficha técnica de seguridad del material (MSDS) 

MMP-2 Inhibitor II - CAS 869577-51-5 - Calbiochem Certificados de análisis

CargoNúmero de lote
444286

Referencias bibliográficas

Visión general referencias
Ikejiri, M., et al. 2005. J. Biol. Chem. 280, 33992.
Ficha técnica

Note that this data sheet is not lot-specific and is representative of the current specifications for this product. Please consult the vial label and the certificate of analysis for information on specific lots. Also note that shipping conditions may differ from storage conditions.

Revision13-April-2011 RFH
Synonyms(4-(4-(Methanesulfonamido)phenoxy)phenylsulfonyl)methyloxirane
DescriptionAn oxirane analog of SB-3CT, pMS (Cat. No. 444285) that acts as a selective, active site-binding, irreversible inhibitor of MMP-2 (Ki = 2.4 µM). Although less potent, it exhibits enhanced selectivity towards MMP-2 (Ki = 45 and 379 µM for MMP-1 and MMP-7, respectively) than SB-3CT, pMS.
FormWhite solid
Intert gas (Yes/No) Packaged under inert gas
CAS number869577-51-5
Chemical formulaC₁₆H₁₇NO₆S₂
Structure formulaStructure formula
Purity≥97% by HPLC
SolubilityDMSO (200 mg/ml)
Storage Protect from moisture
Protect from light
-20°C
Do Not Freeze Ok to freeze
Special InstructionsFollowing reconstitution, aliquot and freeze (-20°C). Stock solutions are stable for up to 1 month at -20°C.
Toxicity Standard Handling
ReferencesIkejiri, M., et al. 2005. J. Biol. Chem. 280, 33992.