420134 Sigma-AldrichJNK Inhibitor VII, TAT-TI-JIP153-163, Cell-Permeable - Calbiochem
The JNK Inhibitor VII, TAT-TI-JIP153-163, Cell-Permeable controls the biological activity of JNK. This small molecule/inhibitor is primarily used for Phosphorylation & Dephosphorylation applications.
More>> The JNK Inhibitor VII, TAT-TI-JIP153-163, Cell-Permeable controls the biological activity of JNK. This small molecule/inhibitor is primarily used for Phosphorylation & Dephosphorylation applications. Less<<Ficha de datos de seguridad (MSDS o SDS), certificado de análisis y de calidad (CoA y CoQ), expedientes, folletos y otros documentos disponibles.
Sinónimos: H₂N-YGRKKRRQRRR-RPKRPTTLNLF-NH₂, TAT₃₈₋₄₈ -Truncated Inhibitor based on JNK-Interacting Protein 1
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Descripción
| Replacement Information |
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Tabla espec. clave
| Empirical Formula |
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| C₁₂₅H₂₂₀N₅₂O₂₇ |
Products
| Número de referencia | Embalaje | Cant./Env. | |
|---|---|---|---|
| 420134-2MG | Ampolla de plást. | 2 mg |
| Description | |
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| Overview | The non-permeant JNK inhibitor peptide TI-JIP153-163 (Cat. No. 420133) is made cell-permeable with an N-terminal TAT protein transduction domain sequence. Shown to offer neuroprotection in a rat ischemic brain injury model in in vivo. |
| Catalogue Number | 420134 |
| Brand Family | Calbiochem® |
| Synonyms | H₂N-YGRKKRRQRRR-RPKRPTTLNLF-NH₂, TAT₃₈₋₄₈ -Truncated Inhibitor based on JNK-Interacting Protein 1 |
| Product Information | |
|---|---|
| ATP Competitive | N |
| Form | Lyophilized |
| Formulation | Supplied as a trifluoroacetate salt. |
| Hill Formula | C₁₂₅H₂₂₀N₅₂O₂₇ |
| Chemical formula | C₁₂₅H₂₂₀N₅₂O₂₇ |
| Hygroscopic | Hygroscopic |
| Reversible | N |
| Quality Level | MQ100 |
| Applications |
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| Biological Information | |
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| Primary Target | JNK |
| Purity | ≥97% by HPLC |
| Physicochemical Information | |
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| Cell permeable | Y |
| Peptide Sequence | H-Tyr-Gly-Arg-Lys-Lys-Arg-Arg-Gln-Arg-Arg-Arg-Arg-Pro-Lys-Arg-Pro-Thr-Thr-Leu-Asn-Leu-Phe-NH₂ |
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| Materials Information |
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| Toxicological Information |
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| Safety Information according to GHS |
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| Safety Information |
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| Product Usage Statements |
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| Packaging Information | |
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| Packaged under inert gas | Packaged under inert gas |
| Transport Information |
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| Supplemental Information |
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| Specifications |
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| Global Trade Item Number | |
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| Número de referencia | GTIN |
| 420134-2MG | 04055977187649 |
Documentation
JNK Inhibitor VII, TAT-TI-JIP153-163, Cell-Permeable - Calbiochem Ficha datos de seguridad (MSDS)
| Título |
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JNK Inhibitor VII, TAT-TI-JIP153-163, Cell-Permeable - Calbiochem Certificados de análisis
| Cargo | Número de lote |
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| 420134 |
Referencias bibliográficas
| Visión general referencias |
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| Guan, Q.H., et al. 2006. Neuroscience, 139, 609. Barr, R.K., et al. 2004. J. Biol. Chem. 279, 36327. Bogoyevitch, M.A., et al. 2003. Cell. Mol. Biol. Lett. 8, 550. Barr, R.K., et al. 2002. J. Biol. Chem. 277, 10987. |
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Note that this data sheet is not lot-specific and is representative of the current specifications for this product. Please consult the vial label and the certificate of analysis for information on specific lots. Also note that shipping conditions may differ from storage conditions.
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