Millipore Sigma Vibrant Logo
Atención: Nos hemos mudado. Los productos Merck Millipore ya no pueden adquirirse en MerckMillipore.comMás información

504776 InSolution™ Cytochalasin D, Zygosporium mansonii - CAS 22144-77-0 - Calbiochem

Ficha de datos de seguridad (MSDS o SDS), certificado de análisis y de calidad (CoA y CoQ), expedientes, folletos y otros documentos disponibles.

Sinónimos: Lygosporin A, Zygosporin A, NSC 209835

Primary Target: microfilaments
504776
Purchase on Sigma-Aldrich

Descripción

Replacement Information

Tabla espec. clave

CAS #Empirical Formula
22144-77-0C₃₀H₃₇NO₆

Products

Número de referenciaEmbalaje Cant./Env.
5047760001 Frasco de vidrio 1 mg
Description
Catalogue Number504776
Brand Family Calbiochem®
SynonymsLygosporin A, Zygosporin A, NSC 209835
References
ReferencesSasaki, H., et al. 1995. Proc. Natl. Acad. Sci. USA 92, 2026.
Blankson, H., et al. 1995. Exp. Cell Res. 218, 522.
Melamed, I., et al. 1995. Biochem. Biophys. Res. Commun. 209, 1102.
Verschueren, H., et al. 1995. Eur. J. Cell Biol. 66, 335.
Aszalos, A., et al. 1994. Cell Immunol. 157, 81.
Wang, W.H., et al. 1994. Am. J. Physiol. 267, F592.
Betina, V., and Micekova, D. 1972. Chem. Abstr. 77, 160508q.
Katagiri, K., and Matsuura, S. 1971. J. Antibiot. 24, 722.
Product Information
CAS number22144-77-0
FormLiquid
FormulationA 10 mM (1 mg/197 µL) sterile-filtered solution of Cytochalasin D, Zygosporium mansonii (Cat. No. 250255) in DMSO.
Hill FormulaC₃₀H₃₇NO₆
Chemical formulaC₃₀H₃₇NO₆
Hygroscopic Hygroscopic
ReversibleY
Structure formula ImageStructure formula Image
Quality LevelMQ100
Applications
Biological Information
Primary Targetmicrofilaments
Purity≥98% by TLC
Physicochemical Information
Cell permeableY
Dimensions
Materials Information
Toxicological Information
Safety Information according to GHS
Safety Information
R PhraseR: 36/38

Irritating to eyes and skin.
S PhraseS: 24/25

Avoid contact with skin and eyes.
Product Usage Statements
Storage and Shipping Information
Ship Code Dry Ice Only
Toxicity Irritant
Storage ≤ -70°C
Protect from Light Protect from light
Hygroscopic Hygroscopic
Avoid freeze/thaw Avoid freeze/thaw
Do not freeze Ok to freeze
Special InstructionsFollowing initial thaw, aliquot and freeze (-70°C). Aliquots are stable for up to 6 months at -70°C.
Packaging Information
Packaged under inert gas Packaged under inert gas
Transport Information
Supplemental Information
Specifications
Global Trade Item Number
Número de referencia GTIN
5047760001 04055977244120

Documentation

InSolution™ Cytochalasin D, Zygosporium mansonii - CAS 22144-77-0 - Calbiochem Ficha datos de seguridad (MSDS)

Título

Ficha técnica de seguridad del material (MSDS) 

Referencias bibliográficas

Visión general referencias
Sasaki, H., et al. 1995. Proc. Natl. Acad. Sci. USA 92, 2026.
Blankson, H., et al. 1995. Exp. Cell Res. 218, 522.
Melamed, I., et al. 1995. Biochem. Biophys. Res. Commun. 209, 1102.
Verschueren, H., et al. 1995. Eur. J. Cell Biol. 66, 335.
Aszalos, A., et al. 1994. Cell Immunol. 157, 81.
Wang, W.H., et al. 1994. Am. J. Physiol. 267, F592.
Betina, V., and Micekova, D. 1972. Chem. Abstr. 77, 160508q.
Katagiri, K., and Matsuura, S. 1971. J. Antibiot. 24, 722.
Ficha técnica

Note that this data sheet is not lot-specific and is representative of the current specifications for this product. Please consult the vial label and the certificate of analysis for information on specific lots. Also note that shipping conditions may differ from storage conditions.

Revision14-June-2013 JSW
SynonymsLygosporin A, Zygosporin A, NSC 209835
DescriptionA cell-permeable fungal toxin that is approximately 10 times more potent than cytochalasin B (Cat. No. 250233) in inhibiting actin filament function. Does not inhibit monosaccharide transport across cell membranes. Inhibits cytoplasmic division by blocking the formation of contractile microfilaments at 10 µM. Inactivates low conductance K+ channels. Also modulates CD4 cross-linking in T lymphocytes and increases intracellular Ca2+ levels. Cytochalasin D also exhibits antibiotic and anti-tumor properties.
FormLiquid
FormulationA 10 mM (1 mg/197 µL) sterile-filtered solution of Cytochalasin D, Zygosporium mansonii (Cat. No. 250255) in DMSO.
Intert gas (Yes/No) Packaged under inert gas
CAS number22144-77-0
Chemical formulaC₃₀H₃₇NO₆
Structure formulaStructure formula
Purity≥98% by TLC
Storage Protect from light
Avoid freeze/thaw
≤ -70°C
Hygroscopic
Do Not Freeze Ok to freeze
Special InstructionsFollowing initial thaw, aliquot and freeze (-70°C). Aliquots are stable for up to 6 months at -70°C.
Toxicity Irritant
ReferencesSasaki, H., et al. 1995. Proc. Natl. Acad. Sci. USA 92, 2026.
Blankson, H., et al. 1995. Exp. Cell Res. 218, 522.
Melamed, I., et al. 1995. Biochem. Biophys. Res. Commun. 209, 1102.
Verschueren, H., et al. 1995. Eur. J. Cell Biol. 66, 335.
Aszalos, A., et al. 1994. Cell Immunol. 157, 81.
Wang, W.H., et al. 1994. Am. J. Physiol. 267, F592.
Betina, V., and Micekova, D. 1972. Chem. Abstr. 77, 160508q.
Katagiri, K., and Matsuura, S. 1971. J. Antibiot. 24, 722.