Millipore Sigma Vibrant Logo
Atención: Nos hemos mudado. Los productos Merck Millipore ya no pueden adquirirse en MerckMillipore.comMás información

382110 Histone Acetyltransferase Inhibitor II - CAS 932749-62-7 - Calbiochem

The Histone Acetyltransferase Inhibitor II, also referenced under CAS 932749-62-7, controls the biological activity of Histone Acetyltransferase. This small molecule/inhibitor is primarily used for Ce

 More>>
Ficha de datos de seguridad (MSDS o SDS), certificado de análisis y de calidad (CoA y CoQ), expedientes, folletos y otros documentos disponibles.

Sinónimos: 2,6-bis-(3-Bromo-4-hydroxybenzylidene)cyclohexanone, HAT Inhibitor II, p300/CBP Inhibitor II, GCN5 Inhibitor I

382110
Purchase on Sigma-Aldrich

Descripción

Tabla espec. clave

CAS #Empirical Formula
932749-62-7C₂₀H₁₆Br₂O₃

Products

Número de referenciaEmbalaje Cant./Env.
382110-10MG Ampolla de plást. 10 mg
Añadir a favoritos
Description
OverviewA cell-permeable bis-arylidene cyclohexanone compound that acts as a p300/CBP-selective histone acetyltransferase inhibitor (IC50 = 5 µM), while it affects GCN5 and PCAF only at much higher concentrations (30% and 0% inhibition, respectively, at 5 µM inhibitor concentration). Shown to decrease histone H3 acetylation (IC50 ≤ 40 µM) and induce chromatin condensation in HeLa cells.
Catalogue Number382110
Brand Family Calbiochem®
Synonyms2,6-bis-(3-Bromo-4-hydroxybenzylidene)cyclohexanone, HAT Inhibitor II, p300/CBP Inhibitor II, GCN5 Inhibitor I
References
ReferencesCosti, R., et al. 2007. J. Med. Chem. 50, 1973.
Product Information
CAS number932749-62-7
FormYellow solid
Hill FormulaC₂₀H₁₆Br₂O₃
Chemical formulaC₂₀H₁₆Br₂O₃
Structure formula ImageStructure formula Image
Quality LevelMQ100
Biological Information
Purity≥97% by HPLC
Storage and Shipping Information
Ship Code Ambient Temperature Only
Toxicity Standard Handling
Storage +2°C to +8°C
Protect from Light Protect from light
Do not freeze Ok to freeze
Special InstructionsFollowing reconstitution, aliquot and freeze (-20°C). Stock solutions are stable for up to 1 month.
Packaging Information
Packaged under inert gas Packaged under inert gas
Global Trade Item Number
Número de referencia GTIN
382110-10MG 04055977213096