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508506 Gabapentin - CAS 60142-96-3 - Calbiochem

A water soluble GABA analog that interacts with voltage-gated calcium channels in cortical neurons.

Gabapentin - CAS 60142-96-3 - Calbiochem: Ficha de datos de seguridad (MSDS o SDS), certificado de análisis y de calidad (CoA y CoQ), expedientes, folletos y otros documentos disponibles.

Sinónimos: L-type Voltage Gated Ca2+ Channel Blocke, Gabapentin

Primary Target: α2δ subunit of L-type voltage gated Ca2+ channels
508506
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Descripción

Replacement Information

Tabla espec. clave

CAS #Empirical Formula
60142-96-3C₉H₁₇NO₂

Products

Número de referenciaEmbalaje Cant./Env.
5085060001 Frasco de vidrio 10 mg
Description
OverviewA water soluble GABA analog originally developed to treat epilepsy and neuropathic pain but is not believed to act on the same brain receptors. Gabapentin interacts with voltage-gated calcium channels in cortical neurons. It binds to the α2δ subunit (1 and 2) and has been found to reduce calcium currents after chronic but not acute application via an effect on trafficking of voltage-dependent calcium channels in the central nervous system.
Catalogue Number508506
Brand Family Calbiochem®
SynonymsL-type Voltage Gated Ca2+ Channel Blocke, Gabapentin
References
ReferencesEroglu, C. et al. 2009. Cell. 139, 380.
Hendrich, J. et al. 2008. Proc. Natl. Acad. Sci. USA 105, 3628.
Davies, A. et al. 2007. Trends Pharmacol. Sci. 28, 220.
Product Information
CAS number60142-96-3
FormWhite solid
Hill FormulaC₉H₁₇NO₂
Chemical formulaC₉H₁₇NO₂
Structure formula ImageStructure formula Image
Quality LevelMQ100
Applications
Biological Information
Primary Targetα2δ subunit of L-type voltage gated Ca2+ channels
Purity≥98% by HPLC
Physicochemical Information
Dimensions
Materials Information
Toxicological Information
Safety Information according to GHS
Safety Information
Product Usage Statements
Storage and Shipping Information
Ship Code Shipped at Ambient Temperature or with Blue Ice or with Dry Ice
Toxicity Standard Handling
Storage +2°C to +8°C
Protect from Light Protect from light
Do not freeze Ok to freeze
Special InstructionsFollowing reconstitution, aliquot and freeze (-20°C). Stock solutions are stable for up to 3 months at -20°C.
Packaging Information
Transport Information
Supplemental Information
Specifications
Global Trade Item Number
Número de referencia GTIN
5085060001 04055977261998

Documentation

Gabapentin - CAS 60142-96-3 - Calbiochem Ficha datos de seguridad (MSDS)

Título

Ficha técnica de seguridad del material (MSDS) 

Referencias bibliográficas

Visión general referencias
Eroglu, C. et al. 2009. Cell. 139, 380.
Hendrich, J. et al. 2008. Proc. Natl. Acad. Sci. USA 105, 3628.
Davies, A. et al. 2007. Trends Pharmacol. Sci. 28, 220.
Ficha técnica

Note that this data sheet is not lot-specific and is representative of the current specifications for this product. Please consult the vial label and the certificate of analysis for information on specific lots. Also note that shipping conditions may differ from storage conditions.

Revision24-January-2014 JSW
SynonymsL-type Voltage Gated Ca2+ Channel Blocke, Gabapentin
DescriptionA water soluble GABA analog originally developed to treat epilepsy and neuropathic pain but is not believed to act on the same brain receptors. Gabapentin interacts with voltage-gated calcium channels in cortical neurons. It binds to the α2δ subunit (1 and 2) and has been found to reduce calcium currents after chronic but not acute application via an effect on trafficking of voltage-dependent calcium channels in the central nervous system.
FormWhite solid
CAS number60142-96-3
Chemical formulaC₉H₁₇NO₂
Structure formulaStructure formula
Purity≥98% by HPLC
SolubilityH₂O (100 mM)
Storage Protect from light
+2°C to +8°C
Do Not Freeze Ok to freeze
Special InstructionsFollowing reconstitution, aliquot and freeze (-20°C). Stock solutions are stable for up to 3 months at -20°C.
Toxicity Standard Handling
ReferencesEroglu, C. et al. 2009. Cell. 139, 380.
Hendrich, J. et al. 2008. Proc. Natl. Acad. Sci. USA 105, 3628.
Davies, A. et al. 2007. Trends Pharmacol. Sci. 28, 220.