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505277 GTS-21 Dihydrochloride (DMBX-A) - CAS 156223-05-1 - Calbiochem

Ficha de datos de seguridad (MSDS o SDS), certificado de análisis y de calidad (CoA y CoQ), expedientes, folletos y otros documentos disponibles.

Sinónimos: E)-3-(2,4-dimethoxybenzylidene)-3,4,5,6-tetrahydro-2,3ʹ-bipyridine, DMBX-A, α7 nAChR Agonist, GTS-21, Alpha 7 Nicotinic Acetylcholine Receptor Agonist, GTS-21

Primary Target: α7 nAChR
505277
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Descripción

Replacement Information

Tabla espec. clave

CAS #Empirical Formula
156223-05-1C₁₉H₂₀N₂O₂•2HCl

Products

Número de referenciaEmbalaje Cant./Env.
5052770001 Frasco de vidrio 10 mg
Description
OverviewA partial agonist selective for α7 nAChRs (EC50 = 10 µM). Used in neuroimmunology studies, cardiovascular disease research, and Alzheimer's disease studies.
Catalogue Number505277
Brand Family Calbiochem®
SynonymsE)-3-(2,4-dimethoxybenzylidene)-3,4,5,6-tetrahydro-2,3ʹ-bipyridine, DMBX-A, α7 nAChR Agonist, GTS-21, Alpha 7 Nicotinic Acetylcholine Receptor Agonist, GTS-21
References
ReferencesKox, M., et al. 2011. Br. J. Anaesth. 107, 559.
Kox, M., et al., 2011. Shock. 36, 5.
Rosas-Ballina, M., et al. 2009. Mol. Med. 15, 195.
Briggs, A., et al. 1997. Pharmacol. Biochem. Behav. 57, 231.
Product Information
CAS number156223-05-1
FormYellow solid
Hill FormulaC₁₉H₂₀N₂O₂•2HCl
Chemical formulaC₁₉H₂₀N₂O₂•2HCl
ReversibleY
Structure formula ImageStructure formula Image
Quality LevelMQ100
Applications
Biological Information
Primary Targetα7 nAChR
Purity≥98% by HPLC
Physicochemical Information
Dimensions
Materials Information
Toxicological Information
Safety Information according to GHS
Safety Information
Product Usage Statements
Storage and Shipping Information
Ship Code Shipped at Ambient Temperature or with Blue Ice or with Dry Ice
Toxicity Standard Handling
Storage -20°C
Protect from Light Protect from light
Do not freeze Ok to freeze
Special InstructionsFollowing reconstitution, aliquot and freeze (-20°C). Stock solutions are stable for up to 3 months at -20°C.
Packaging Information
Transport Information
Supplemental Information
Specifications
Global Trade Item Number
Número de referencia GTIN
5052770001 04055977243635

Documentation

GTS-21 Dihydrochloride (DMBX-A) - CAS 156223-05-1 - Calbiochem Ficha datos de seguridad (MSDS)

Título

Ficha técnica de seguridad del material (MSDS) 

Referencias bibliográficas

Visión general referencias
Kox, M., et al. 2011. Br. J. Anaesth. 107, 559.
Kox, M., et al., 2011. Shock. 36, 5.
Rosas-Ballina, M., et al. 2009. Mol. Med. 15, 195.
Briggs, A., et al. 1997. Pharmacol. Biochem. Behav. 57, 231.
Ficha técnica

Note that this data sheet is not lot-specific and is representative of the current specifications for this product. Please consult the vial label and the certificate of analysis for information on specific lots. Also note that shipping conditions may differ from storage conditions.

Revision17-July-2013 JSW
SynonymsE)-3-(2,4-dimethoxybenzylidene)-3,4,5,6-tetrahydro-2,3ʹ-bipyridine, DMBX-A, α7 nAChR Agonist, GTS-21, Alpha 7 Nicotinic Acetylcholine Receptor Agonist, GTS-21
DescriptionA partial agonist selective for α7 nAChRs (EC50 = 10 µM). Used in neuroimmunology studies, cardiovascular disease research, and Alzheimer's disease studies.
FormYellow solid
CAS number156223-05-1
Chemical formulaC₁₉H₂₀N₂O₂•2HCl
Structure formulaStructure formula
Purity≥98% by HPLC
SolubilityDMSO (100 mM) or H₂O (100 mM)
Storage Protect from light
-20°C
Do Not Freeze Ok to freeze
Special InstructionsFollowing reconstitution, aliquot and freeze (-20°C). Stock solutions are stable for up to 3 months at -20°C.
Toxicity Standard Handling
ReferencesKox, M., et al. 2011. Br. J. Anaesth. 107, 559.
Kox, M., et al., 2011. Shock. 36, 5.
Rosas-Ballina, M., et al. 2009. Mol. Med. 15, 195.
Briggs, A., et al. 1997. Pharmacol. Biochem. Behav. 57, 231.