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219419 Cathepsin Inhibitor III - Calbiochem

The Cathepsin Inhibitor III controls the biological activity of Cathepsin. This small molecule/inhibitor is primarily used for Protease Inhibitors applications.

Cathepsin Inhibitor III - Calbiochem: Ficha de datos de seguridad (MSDS o SDS), certificado de análisis y de calidad (CoA y CoQ), expedientes, folletos y otros documentos disponibles.

Sinónimos: Z-FG-NHO-BzOME

Primary Target: cathepsin B
219419
Purchase on Sigma-Aldrich

Descripción

Replacement Information

Tabla espec. clave

Empirical Formula
C₂₇H₂₇N₃O₇

Products

Número de referenciaEmbalaje Cant./Env.
219419-1MG Ampolla de plást. 1 mg
Description
OverviewCysteine protease inhibitor. Selectively inhibits cathepsin B (k2/Ki = 1 x 104 M-1 sec-1), cathepsin L (k2/Ki = 1.5 x 105 M-1 sec-1), cathepsin S (k2/Ki = 6.6 x 104 M-1 sec-1), and papain (k2/Ki = 1 x 103 M-1 sec-1).
Half-life in buffered solution (pH 5-9) = 37 h (30°C); 300 h (0°C).
Catalogue Number219419
Brand Family Calbiochem®
SynonymsZ-FG-NHO-BzOME
References
ReferencesDemuth, H.-U., et al. 1996. Biochim. Biophys. Acta 1295, 179.
Brömme, D., and Demuth, H.-U. 1994. Methods Enzymol. 244, 671.
Product Information
ATP CompetitiveN
FormWhite solid
Hill FormulaC₂₇H₂₇N₃O₇
Chemical formulaC₂₇H₂₇N₃O₇
ReversibleN
Structure formula ImageStructure formula Image
Quality LevelMQ100
Applications
Biological Information
Primary Targetcathepsin B
Primary Target K<sub>i</sub>k₂/Ki = 1 x 10⁴ M⁻¹ sec⁻¹
Purity>90% by HPLC
Physicochemical Information
Cell permeableN
Peptide SequenceZ-Phe-Gly-NHO-Bz-pOMe
Dimensions
Materials Information
Toxicological Information
Safety Information according to GHS
Safety Information
Product Usage Statements
Storage and Shipping Information
Ship Code Ambient Temperature Only
Toxicity Standard Handling
Storage +15°C to +30°C
Protect from Light Protect from light
Protect from Moisture Protect from moisture
Do not freeze Ok to freeze
Special InstructionsFollowing reconstitution, aliquot and freeze (-20°C). Stock solutions are stable for up to 3 months at -20°C.
Packaging Information
Transport Information
Supplemental Information
Specifications
Global Trade Item Number
Número de referencia GTIN
219419-1MG 04055977218336

Documentation

Cathepsin Inhibitor III - Calbiochem Ficha datos de seguridad (MSDS)

Título

Ficha técnica de seguridad del material (MSDS) 

Cathepsin Inhibitor III - Calbiochem Certificados de análisis

CargoNúmero de lote
219419

Referencias bibliográficas

Visión general referencias
Demuth, H.-U., et al. 1996. Biochim. Biophys. Acta 1295, 179.
Brömme, D., and Demuth, H.-U. 1994. Methods Enzymol. 244, 671.

Folleto

Cargo
Cathepsins and Related Products Technical Bulletin
Ficha técnica

Note that this data sheet is not lot-specific and is representative of the current specifications for this product. Please consult the vial label and the certificate of analysis for information on specific lots. Also note that shipping conditions may differ from storage conditions.

Revision27-September-2007 RFH
SynonymsZ-FG-NHO-BzOME
DescriptionCysteine protease inhibitor. Selectively inhibits cathepsin B (k2/Ki = 1.0 x 104 M-1sec-1), cathepsin L (k2/Ki = 1.5 x 105 M-1sec-1), cathepsin S (k2/Ki = 6.6 x 104 M-1sec-1), and papain (k2/Ki = 1.0 x 103 M-1sec-1). Half-life in buffered solution (pH 5-9) = 37 h (30°C); 300 h (0°C).
FormWhite solid
Chemical formulaC₂₇H₂₇N₃O₇
Peptide SequenceZ-Phe-Gly-NHO-Bz-pOMe
Structure formulaStructure formula
Purity>90% by HPLC
SolubilityDMSO (5 mg/ml) or Ethanol (1 mg/ml)
Storage Protect from moisture
Protect from light
+15°C to +30°C
Do Not Freeze Ok to freeze
Special InstructionsFollowing reconstitution, aliquot and freeze (-20°C). Stock solutions are stable for up to 3 months at -20°C.
Toxicity Standard Handling
ReferencesDemuth, H.-U., et al. 1996. Biochim. Biophys. Acta 1295, 179.
Brömme, D., and Demuth, H.-U. 1994. Methods Enzymol. 244, 671.