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218728 Caspase-9 Inhibitor III - CAS 403848-57-7 - Calbiochem

The Caspase-9 Inhibitor III, also referenced under CAS 403848-57-7, controls the biological activity of Caspase-9. This small molecule/inhibitor is primarily used for Cancer applications.

Ficha de datos de seguridad (MSDS o SDS), certificado de análisis y de calidad (CoA y CoQ), expedientes, folletos y otros documentos disponibles.

Sinónimos: Ac-LEHD-CMK

Primary Target: caspase-9
218728
Purchase on Sigma-Aldrich

Descripción

Replacement Information

Tabla espec. clave

CAS #Empirical Formula
403848-57-7C₂₄H₃₅ClN₆O₉

Products

Número de referenciaEmbalaje Cant./Env.
218728-1MG Ampolla de plást. 1 mg
Description
OverviewA potent, irreversible inhibitor of caspase-9. Reported to reduce myocardial infarct size during reperfusion (~70 nM).
Catalogue Number218728
Brand Family Calbiochem®
SynonymsAc-LEHD-CMK
References
ReferencesMocanu, M.M., et al. 2000. Br. J. Pharmacol. 130, 197.
Product Information
CAS number403848-57-7
ATP CompetitiveN
FormWhite solid
FormulationSupplied as a trifluoroacetate salt.
Hill FormulaC₂₄H₃₅ClN₆O₉
Chemical formulaC₂₄H₃₅ClN₆O₉
ReversibleN
Structure formula ImageStructure formula Image
Quality LevelMQ100
Applications
Biological Information
Primary Targetcaspase-9
Primary Target IC<sub>50</sub>70 nM against caspase-9
Purity≥95% by HPLC
Physicochemical Information
Cell permeableY
Peptide SequenceAc-Leu-Glu-His-Asp-CMK
Dimensions
Materials Information
Toxicological Information
Safety Information according to GHS
Safety Information
Product Usage Statements
Storage and Shipping Information
Ship Code Ambient Temperature Only
Toxicity Standard Handling
Storage -20°C
Protect from Moisture Protect from moisture
Do not freeze Ok to freeze
Special InstructionsFollowing reconstitution aliquot and freeze (-20°C). Stock solutions are stable for up to 6 months at -20°C.
Packaging Information
Transport Information
Supplemental Information
Specifications
Global Trade Item Number
Número de referencia GTIN
218728-1MG 07790788048594

Documentation

Caspase-9 Inhibitor III - CAS 403848-57-7 - Calbiochem Ficha datos de seguridad (MSDS)

Título

Ficha técnica de seguridad del material (MSDS) 

Caspase-9 Inhibitor III - CAS 403848-57-7 - Calbiochem Certificados de análisis

CargoNúmero de lote
218728

Referencias bibliográficas

Visión general referencias
Mocanu, M.M., et al. 2000. Br. J. Pharmacol. 130, 197.

Folleto

Cargo
Caspases and other Apoptosis Related Tools Brochure
Ficha técnica

Note that this data sheet is not lot-specific and is representative of the current specifications for this product. Please consult the vial label and the certificate of analysis for information on specific lots. Also note that shipping conditions may differ from storage conditions.

Revision31-March-2011 RFH
SynonymsAc-LEHD-CMK
DescriptionA potent and irreversible inhibitor of caspase-9 (ICE-LAP6, Mch6). Reported to reduce myocardial infarct size during reperfusion (~70 nM).
FormWhite solid
FormulationSupplied as a trifluoroacetate salt.
CAS number403848-57-7
Chemical formulaC₂₄H₃₅ClN₆O₉
Peptide SequenceAc-Leu-Glu-His-Asp-CMK
Structure formulaStructure formula
Purity≥95% by HPLC
SolubilityDMSO (5 mg/ml) or (1 mg/ml) H₂O
Storage Protect from moisture
-20°C
Do Not Freeze Ok to freeze
Special InstructionsFollowing reconstitution aliquot and freeze (-20°C). Stock solutions are stable for up to 6 months at -20°C.
Toxicity Standard Handling
ReferencesMocanu, M.M., et al. 2000. Br. J. Pharmacol. 130, 197.