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200484 Bestatin - CAS 58970-76-6 - Calbiochem

Bestatin, CAS 58970-76-6, is a potent inhibitor of surface aminopeptidases, notably aminopeptidase B, N, and leucine aminopeptidase. Activates macrophages and T lymphocytes.

Bestatin - CAS 58970-76-6 - Calbiochem: Ficha de datos de seguridad (MSDS o SDS), certificado de análisis y de calidad (CoA y CoQ), expedientes, folletos y otros documentos disponibles.

Sinónimos: [(2S,3R)-3-Amino-2-hydroxy-4-phenylbutanoyl]-Leu

Primary Target: amino peptidase b
200484
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Descripción

Replacement Information

Tabla espec. clave

CAS #Empirical Formula
58970-76-6C₁₆H₂₄N₂O₄

Products

Número de referenciaEmbalaje Cant./Env.
200484-10MG Ampolla de plást. 10 mg
Description
OverviewBinds to cell surfaces and inhibits surface aminopeptidases, notably aminopeptidase B and leucine aminopeptidase. Also acts as a potent aminopeptidase N inhibitor. Activates macrophages and T lymphocytes. Has antitumor properties. Also available as a 50 mM solution in water (Cat. No. 200488).
Catalogue Number200484
Brand Family Calbiochem®
Synonyms[(2S,3R)-3-Amino-2-hydroxy-4-phenylbutanoyl]-Leu
References
ReferencesInoue, T., et al. 1994. J. Clin. Endocrinol. Metab. 79, 171.
Taylor, A., et al. 1993. Biochemistry 32, 784.
Ishida, J.I., et al. 1984. J. Chromatogr. 305, 381.
Umezawa, H. 1982. Annu. Rev. Microbiol. 36, 75.
Product Information
CAS number58970-76-6
ATP CompetitiveN
FormWhite crystalline solid
Hill FormulaC₁₆H₂₄N₂O₄
Chemical formulaC₁₆H₂₄N₂O₄
ReversibleN
Quality LevelMQ100
Applications
ApplicationBestatin, CAS 58970-76-6, is a potent inhibitor of surface aminopeptidases, notably aminopeptidase B, N, and leucine aminopeptidase. Activates macrophages and T lymphocytes.
Biological Information
Primary Targetamino peptidase b
Purity>99% by HPLC
Physicochemical Information
Cell permeableN
Dimensions
Materials Information
Toxicological Information
Safety Information according to GHS
RTECSOH2915000
Safety Information
Product Usage Statements
Storage and Shipping Information
Ship Code Ambient Temperature Only
Toxicity Standard Handling
Storage +2°C to +8°C
Do not freeze Ok to freeze
Special InstructionsFollowing reconstitution, aliquot and freeze (-20°C). DMSO and methanol stock solutions are stable for up to 1 month at -20°C.
Packaging Information
Transport Information
Supplemental Information
Specifications
Global Trade Item Number
Número de referencia GTIN
200484-10MG 04055977221459

Documentation

Bestatin - CAS 58970-76-6 - Calbiochem Ficha datos de seguridad (MSDS)

Título

Ficha técnica de seguridad del material (MSDS) 

Bestatin - CAS 58970-76-6 - Calbiochem Certificados de análisis

CargoNúmero de lote
200484

Referencias bibliográficas

Visión general referencias
Inoue, T., et al. 1994. J. Clin. Endocrinol. Metab. 79, 171.
Taylor, A., et al. 1993. Biochemistry 32, 784.
Ishida, J.I., et al. 1984. J. Chromatogr. 305, 381.
Umezawa, H. 1982. Annu. Rev. Microbiol. 36, 75.

Citas

Título
  • Anthony R. White, et al. (2006) Degradation of the alzheimer disease amyloid -peptide by metal-dependent up-regulation of metalloprotease activity. journal of Biological Chemistry 281, 17670-17680.
    		•
    Ficha técnica

    Note that this data sheet is not lot-specific and is representative of the current specifications for this product. Please consult the vial label and the certificate of analysis for information on specific lots. Also note that shipping conditions may differ from storage conditions.

    Revision13-May-2013 JSW
    Synonyms[(2S,3R)-3-Amino-2-hydroxy-4-phenylbutanoyl]-Leu
    DescriptionBinds to cell surfaces and inhibits surface aminopeptidases, notably aminopeptidase B and leucine aminopeptidase. Also acts as a potent aminopeptidase N inhibitor. Activates macrophages and T lymphocytes. Has anti-tumor properties. Effective at a concentration of 1-10 µM.
    FormWhite crystalline solid
    CAS number58970-76-6
    RTECSOH2915000
    Chemical formulaC₁₆H₂₄N₂O₄
    Purity>99% by HPLC
    SolubilityDMSO (2 mg/ml) or Methanol (5 mg/ml). Unstable in aqueous solution; dilute just prior to use.
    Storage +2°C to +8°C
    Do Not Freeze Ok to freeze
    Special InstructionsFollowing reconstitution, aliquot and freeze (-20°C). DMSO and methanol stock solutions are stable for up to 1 month at -20°C.
    Toxicity Standard Handling
    Merck USA index14, 9842
    ReferencesInoue, T., et al. 1994. J. Clin. Endocrinol. Metab. 79, 171.
    Taylor, A., et al. 1993. Biochemistry 32, 784.
    Ishida, J.I., et al. 1984. J. Chromatogr. 305, 381.
    Umezawa, H. 1982. Annu. Rev. Microbiol. 36, 75.
    Citation
  • Anthony R. White, et al. (2006) Degradation of the alzheimer disease amyloid -peptide by metal-dependent up-regulation of metalloprotease activity. journal of Biological Chemistry 281, 17670-17680.
    		•