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ABE473 Anti-hRNF20 Antibody

ABE473
100 µL  
Purchase on Sigma-Aldrich

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Descripción

Replacement Information

Ofertas especiales

Tabla espec. clave

Species ReactivityKey ApplicationsHostFormatAntibody Type
H, M, RWBRbAffinity PurifiedPolyclonal Antibody
Description
Catalogue NumberABE473
DescriptionAnti-hRNF20 Antibody
Alternate Names
  • E3 ubiquitin-protein ligase BRE1A
  • BRE1-A
  • hBRE1
  • RING finger protein 20
  • hRNF20
Background InformationBRE1-A (E3 ubiquitin-protein ligase BRE1A) also known by it's gene name hRNF20, plays a role in histone code and gene regulation as a component of the RNF20/40 E3 ubiquitin-protein ligase complex. That complex mediates monoubiquitination of 'Lys-120' of histone H2B,which is a specific tag for epigenetic transcriptional activation as well as a prerequisite for histone H3 'Lys-4' (H3K4me) and 'Lys-79' (H3K79me) methylation.
References
Product Information
FormatAffinity Purified
Control
  • A431 cell lysate
PresentationPurified rabbit polyclonal in buffer containing 0.1 M Tris-Glycine (pH 7.4), 150 mM NaCl with 0.05% sodium azide.
Quality LevelMQ100
Applications
ApplicationThis hRNF20 antibody is validated for use in WB for the detection of the hRNF20 protein.
Key Applications
  • Western Blotting
Biological Information
ImmunogenGST-tagged recombinant protein corresponding to human hRNF20.
ConcentrationPlease refer to the Certificate of Analysis for the lot-specific concentration.
HostRabbit
Species Reactivity
  • Human
  • Mouse
  • Rat
Antibody TypePolyclonal Antibody
Entrez Gene Number
Gene Symbol
  • RNF20
  • BRE1A
Purification MethodAffinity Purfied
UniProt Number
Molecular Weight~113 kDa observed
Physicochemical Information
Dimensions
Materials Information
Toxicological Information
Safety Information according to GHS
Safety Information
Product Usage Statements
Quality AssuranceEvaluated by Western Blotting in A431 cell lysate.

Western Blotting Analysis: A 1:1,000 dilution from a representative lot detected hRNF20 in 10 µg of A431 cell lysate.
Usage Statement
  • Unless otherwise stated in our catalog or other company documentation accompanying the product(s), our products are intended for research use only and are not to be used for any other purpose, which includes but is not limited to, unauthorized commercial uses, in vitro diagnostic uses, ex vivo or in vivo therapeutic uses or any type of consumption or application to humans or animals.
Storage and Shipping Information
Storage ConditionsStable for 1 year at 2-8°C from date of receipt.
Packaging Information
Material Size100 µL
Transport Information
Supplemental Information
Specifications
Global Trade Item Number
Número de referencia GTIN
ABE473 04053252858239