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MABC292 Anti-TAOK1 Antibody (long isoform), clone TAO1_1.2_VMD

This Anti-TAOK1 Antibody (long isoform), clone TAO1_1.2_VMD is validated for use in Western Blotting for the detection of TAOK1 (long isoform).

Ficha de datos de seguridad (MSDS o SDS), certificado de análisis y de calidad (CoA y CoQ), expedientes, folletos y otros documentos disponibles.
Research Category: Apoptosis & Cancer Research Sub-Category: Apoptosis - Additional Gene Symbol: TAOK1, KIAA1361, MAP3K16, MARKK UniProt Number: Q7L7X3
MABC292
100 µg  
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Tabla espec. clave

Species ReactivityKey ApplicationsHostFormatAntibody Type
HWBMPurifiedMonoclonal Antibody
Description
Catalogue NumberMABC292
DescriptionAnti-TAOK1 Antibody (long isoform), clone TAO1_1.2_VMD
Alternate Names
  • Serine/threonine-protein kinase TAO1
  • Kinase from chicken homolog B
  • hKFC-B
  • MARK Kinase
  • MARKK
  • Prostate-derived sterile 20-like kinase 2
  • PSK-2
  • PSK2
  • Prostate-derived STE20-like kinase 2
  • Thousand and one amino acid protein kinase 1
  • TAOK1
  • hTAOK1
Background InformationTAOK1 , also known as Serine/threonine-protein kinase TAO1, Kinase from chicken homolog B, hKFC-B, MARK Kinase, MARKK, Prostate-derived sterile 20-like kinase 2, PSK-2/PSK2, Prostate-derived STE20-like kinase 2, or Thousand and one amino acid protein kinase 1, TAOK1/hTAOK1, and encoded by the gene TAOK1/KIAA1361/MAP3K16/MARKK, is an important serine/threonine protein kinase involved in a variety of processes including p38/MAPK14 stress responses, DNA damage responses and cytoskeleton stability. TAOK1 also acts as regulator of apoptosis and controls the morphological changes associated with apoptosis including cell contraction, membrane blebbing and apoptotic body formation. TAOK1 is expressed in many tissues but highly expressed in testis as well as brain, colon and muscle. TAOK1 is localized to the cytoplasm and a target for caspase-3 as well as SPRED1 a regulator of the MAP kinase cascade.
References
Product Information
FormatPurified
PresentationPurified mouse monoclonal IgG2bκ in buffer containing 0.1 M Tris-Glycine (pH 7.4), 150 mM NaCl with 0.05% sodium azide.
Quality LevelMQ100
Applications
ApplicationThis Anti-TAOK1 Antibody (long isoform), clone TAO1_1.2_VMD is validated for use in Western Blotting for the detection of TAOK1 (long isoform).
Key Applications
  • Western Blotting
Application NotesWestern Blotting Analysis: A representative lot detected TAOK1 in HeLa cell lysate, but not in TAOK1 siRNA transfected HeLa cell lysate (Prof. Viji Draviam, University of Cambridge).
Biological Information
ImmunogenLinear peptide corresponding to the C-terminus of human TAOK1.
EpitopeC-terminus
Clone1.2
Concentration1 mg/mL
HostMouse
IsotypeIgG2bκ
Species Reactivity
  • Human
Antibody TypeMonoclonal Antibody
Entrez Gene Number
Gene Symbol
  • TAOK1
  • KIAA1361
  • MAP3K16
  • MARKK
Purification MethodProtein G Purified
UniProt Number
Molecular Weight~116 kDa observed
Physicochemical Information
Dimensions
Materials Information
Toxicological Information
Safety Information according to GHS
Safety Information
Product Usage Statements
Quality AssuranceEvaluated by Western Blotting in HeLa cell lysate.

Western Blotting Analysis: 0.5 µg/mL of this antibody detected TAOK1 in 10 µg of HeLa cell lysate.
Usage Statement
  • Unless otherwise stated in our catalog or other company documentation accompanying the product(s), our products are intended for research use only and are not to be used for any other purpose, which includes but is not limited to, unauthorized commercial uses, in vitro diagnostic uses, ex vivo or in vivo therapeutic uses or any type of consumption or application to humans or animals.
Storage and Shipping Information
Storage ConditionsStable for 1 year at 2-8°C from date of receipt.
Packaging Information
Material Size100 µg
Transport Information
Supplemental Information
Specifications
Global Trade Item Number
Número de referencia GTIN
MABC292 04053252978753

Documentation

Anti-TAOK1 Antibody (long isoform), clone TAO1_1.2_VMD Ficha datos de seguridad (MSDS)

Título

Ficha técnica de seguridad del material (MSDS) 

Anti-TAOK1 Antibody (long isoform), clone TAO1_1.2_VMD Certificados de análisis

CargoNúmero de lote
Anti-TAOK1 (long isoform), clone TAO1_1.2_VMD - Q2436816 Q2436816
Anti-TAOK1 (long isoform), clone TAO1_1.2_VMD - 3291369 3291369
Anti-TAOK1 (long isoform), clone TAO1_1.2_VMD - 3756183 3756183
Anti-TAOK1 (long isoform), clone TAO1_1.2_VMD - 4175801 4175801

Referencias bibliográficas

Visión general referenciasPub Med ID
TAO1 kinase maintains chromosomal stability by facilitating proper congression of chromosomes.
Shrestha, Roshan L, et al.
Open Biol, 4: (2014)  2014

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