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ABC335 Anti-MTCH2 Antibody

ABC335
100 µg  
Purchase on Sigma-Aldrich

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Descripción

Replacement Information

Ofertas especiales

Tabla espec. clave

Species ReactivityKey ApplicationsHostFormatAntibody Type
H, MWB, IHC, IFRbAffinity PurifiedPolyclonal Antibody
Description
Catalogue NumberABC335
DescriptionAnti-MTCH2 Antibody
Alternate Names
  • MTCH2
  • Mitochondrial carrier homolog 2
  • HSPC032
  • MIMP
  • Met-induced mitochondrial protein
Background InformationMitochondrial carrier homolog 2 (MTCH2) may play a key role in the mitochondrial apoptosis pathway and may induce mitochondrial depolarization. MTCH2 is suggested to catalyze the exchange of substrates across the inner mitochondrial membrane in response to apoptotic signals. Additionally, it is suggested to be targeted by Bid, a pro-apoptotic Bcl-2 family member. The Bcl-2 family of proteins incorporates a number of critical regulators of apoptosis that can be divided into two classes: inhibitors of apoptosis and promoters of cell death. Apoptosis plays a major role in tissue homeostasis, normal organism development, and removal of damaged cells. The disruption of this process has been linked to a variety of diseases such as cancer.
References
Product Information
FormatAffinity Purified
Control
  • HEK293 cell lysate
PresentationPurified rabbit polyclonal in buffer containing PBS with up to 0.1% sodium azide.
Quality LevelMQ100
Applications
ApplicationAnti-MTCH2 Antibody is a highly specific rabbit polyclonal antibody, that targets Mitochondrial carrier homolog 2 & has been tested in western blotting, IHC & Immunofluorescence.
Key Applications
  • Western Blotting
  • Immunohistochemistry
  • Immunofluorescence
Application NotesImmunohistochemistry Analysis: 5 µg/mL from a representative lot detected MTCH2 in mouse kidney tissue.

Immunofluorescence Analysis: 20 μg/mL from a representative lot detected MTCH2 in mouse kidney cells.
Biological Information
ImmunogenKLH-conjugated linear peptide corresponding to human MTCH2.
ConcentrationPlease refer to the Certificate of Analysis for the lot-specific concentration.
HostRabbit
Species Reactivity
  • Human
  • Mouse
Antibody TypePolyclonal Antibody
Gene Symbol
  • Mtch2
Purification MethodAntigen Affinity Purified
UniProt Number
Molecular Weight~34 kDa observed.
Physicochemical Information
Dimensions
Materials Information
Toxicological Information
Safety Information according to GHS
Safety Information
Product Usage Statements
Quality AssuranceEvaluated by Western Blotting in HEK293 cell lysate.

Western Blotting Analysis: 1 µg/mL of this antibody detected MTCH2 in 15 µg of HEK293 cell lysate.
Usage Statement
  • Unless otherwise stated in our catalog or other company documentation accompanying the product(s), our products are intended for research use only and are not to be used for any other purpose, which includes but is not limited to, unauthorized commercial uses, in vitro diagnostic uses, ex vivo or in vivo therapeutic uses or any type of consumption or application to humans or animals.
Storage and Shipping Information
Storage ConditionsStable for 1 year at 2-8°C from date of receipt.
Packaging Information
Material Size100 µg
Transport Information
Supplemental Information
Specifications
Global Trade Item Number
Número de referencia GTIN
ABC335 04053252905070