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MABF1424 Anti-Ly-6G (mouse), PE-Cy7, clone 1A8 Antibody

This Anti-Ly-6G (mouse), PE-Cy7, clone 1A8 Antibody is validated for use in Flow Cytometry for the detection of Ly-6G.

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Research Category: Inflammation & Immunology Research Sub-Category: Immunoglobulins & Immunology Gene Symbol: Ly6g UniProt Number: P35461
MABF1424
25 μg  
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Tabla espec. clave

Species ReactivityKey ApplicationsHostFormatAntibody Type
MFCRPE-Cy7Monoclonal Antibody
Description
Catalogue NumberMABF1424
DescriptionAnti-Ly-6G (mouse), PE-Cy7, clone 1A8 Antibody
Alternate Names
  • Lymphocyte antigen 6G (Ly-6G)
  • Ly-6G.1
  • Ly-6G
Background InformationThe 1A8 antibody binds to mouse Ly-6G, commonly known as Gr-1, a member of the Ly-6 superfamily of GPI-anchored cell surface proteins with roles in cell signaling and cell adhesion. Gr-1 is differentially expressed during development and maturation of cells in the myeloid lineage and is expression at varying stages and levels on monocytes, macrophages, granulocytes, and peripheral neutrophils. In the mouse, the 1A8 antibody is typically used in combination with the macrophage labeling antibody M1/70 (Anti-CD11b) for phenotypic analysis of monocytes, macrophages and granulocytes. Note: for identification of Ly-C, an alternative antibody, clone RB6-8C5, has been reported to cross-react with Ly-6C on cells expressing this antigen (Fleming et al. 1993. J. Immunol. 151: 2399-2408 and Sasmono et al. 2007. J. Leukoc. Biol. 82: 111-123) and has been cited in the literature for identification of Ly-6G/Ly-6C.
Product Information
FormatPE-Cy7
PresentationPurified Rat monoclonal containing 10 mM NaH2PO4, 150 mM NaCl, 0.09% NaN3, 0.1% gelatin, pH7.2.
Quality LevelMQ100
Applications
ApplicationThis Anti-Ly-6G (mouse), PE-Cy7, clone 1A8 Antibody is validated for use in Flow Cytometry for the detection of Ly-6G.
Key Applications
  • Flow Cytometry
Biological Information
ImmunogenImmunogen information for this antibody is proprietary information.
Clone1A8
ConcentrationPlease refer to lot specific datasheet.
HostRat
IsotypeIgG2aκ
Species Reactivity
  • Mouse
Antibody TypeMonoclonal Antibody
Gene Symbol
  • Ly6g
Purification MethodPurified by size-exclusion chromatography
UniProt Number
Product Usage Statements
Quality AssuranceThis monoclonal antibody was purified from tissue culture supernatant via affinity chromatography. The purified antibody was conjugated under optimal conditions, with unreacted dye removed from the preparation.

Flow Cytometry Analysis: 0.25 μg from a representative lot detected Ly-6G in one million C57Bl/6 bone marrow cells.
Usage Statement
  • Unless otherwise stated in our catalog or other company documentation accompanying the product(s), our products are intended for research use only and are not to be used for any other purpose, which includes but is not limited to, unauthorized commercial uses, in vitro diagnostic uses, ex vivo or in vivo therapeutic uses or any type of consumption or application to humans or animals.
Storage and Shipping Information
Storage ConditionsStable for 1 year at 2-8°C from date of receipt.
Note: It is recommended to store the product undiluted at 2-8°C and protected from prolonged exposure to light. Do not freeze.
Packaging Information
Material Size25 μg
Global Trade Item Number
Número de referencia GTIN
MABF1424 04055977291490