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ABS311 Anti-LCN13 Antibody

ABS311
100 µL  
Purchase on Sigma-Aldrich

Ofertas especiales

Descripción

Replacement Information

Ofertas especiales

Tabla espec. clave

Species ReactivityKey ApplicationsHostFormatAntibody Type
MWBRbSerumPolyclonal Antibody
Description
Catalogue NumberABS311
DescriptionAnti-LCN13 Antibody
Alternate Names
  • orant-binding protein 2a
  • Epididymal-specific lipocalin-13
Background InformationEpididymal-specific lipocalin-13 (LCN13) is also called Odorant-binding protein 2a (Obp2a). LCN13 is a secreted protein that is thought to act as a retinoid carrier protein within the epididymis, and have a role in male fertility. LCN13 is expressed in the epididymis.
References
Product Information
FormatSerum
Control
  • Mouse skin tissue lysate
PresentationRabbit polyclonal serum with 0.05% sodium azide.
Quality LevelMQ100
Applications
ApplicationDetect Lipocalin using this rabbit polyclonal antibody, Anti-LCN13 Antibody validated for use in western blotting.
Key Applications
  • Western Blotting
Application NotesWestern Blotting Analysis: A 1:1,000 dilution from a representative lot detected LCN13 in mouse lung tissue lysate.

Western Blotting Analysis: A representative lot from an independent laboratory detected LCN13 in liver, muscle, and pancreas tissues, but not in white adipose tissue, from LCN13 transgenic male mice (Cho, K. W., et al. (2011). Mol Cell Biol. 31(3):450-7.).

Western Blotting Analysis: A representative lot from an independent laboratory detected LCN13 in transfected mouse primary hepotcytes cell lysates (Sheng, L, et al. (2011). J Biol Chem. 286(44):38128-38135.).

Western Blotting Analysis: A representative lot detected LCN13 in mouse adipocyte cell lysates and in certain mouse organ tissues lysates (Zhou, Y. and Rui, L., (2013). Vitam Horm. 91:369-383.).
Biological Information
ImmunogenRecombinant protein corresponding to mouse LCN13.
ConcentrationPlease refer to the Certificate of Analysis for the lot-specific concentration.
HostRabbit
SpecificityThis antibody detects two observed isoforms of LCN13.
Species Reactivity
  • Mouse
Antibody TypePolyclonal Antibody
Entrez Gene Number
Gene Symbol
  • Obp2a
  • Lcn13
Purification MethodUnpurified
UniProt Number
Molecular Weight~20 kDa observed. Two observed isoforms at ~20 kDa and ~28 kDa are likely due to proteolytic cleavage of a common LCN13 precursor (Cho, K. W., et al. (2011). Mol Cell Biol. 31(3):450-7.). Uncharacterized band(s) may be observed in some cell lysates.
Physicochemical Information
Dimensions
Materials Information
Toxicological Information
Safety Information according to GHS
Safety Information
Product Usage Statements
Quality AssuranceEvaluated by Western Blotting in mouse skin tissue lysate.

Western Blotting Analysis: A 1:1,000 dilution of this antibody detected LCN13 in 10 µg of LCN13 mouse skin tissue lysate.
Usage Statement
  • Unless otherwise stated in our catalog or other company documentation accompanying the product(s), our products are intended for research use only and are not to be used for any other purpose, which includes but is not limited to, unauthorized commercial uses, in vitro diagnostic uses, ex vivo or in vivo therapeutic uses or any type of consumption or application to humans or animals.
Storage and Shipping Information
Storage ConditionsStable for 1 year at -20°C from date of receipt.
Handling Recommendations: Upon receipt and prior to removing the cap, centrifuge the vial and gently mix the solution. Aliquot into microcentrifuge tubes and store at -20°C. Avoid repeated freeze/thaw cycles, which may damage IgG and affect product performance.
Packaging Information
Material Size100 µL
Transport Information
Supplemental Information
Specifications
Global Trade Item Number
Número de referencia GTIN
ABS311 04053252916724

Documentation

Anti-LCN13 Antibody Ficha datos de seguridad (MSDS)

Título

Ficha técnica de seguridad del material (MSDS) 

Anti-LCN13 Antibody Certificados de análisis

CargoNúmero de lote
Anti-LCN13 - 3819087 3819087
Anti-LCN13 - Q2218167 Q2218167

Referencias bibliográficas

Visión general referenciasPub Med ID
Lipocalin 13 regulation of glucose and lipid metabolism in obesity.
Zhou, Yingjiang and Rui, Liangyou
Vitam. Horm., 91: 369-83 (2013)  2013

Mostrar resumen
23374724 23374724
Lipocalin 13 protein protects against hepatic steatosis by both inhibiting lipogenesis and stimulating fatty acid β-oxidation.
Sheng, Liang, et al.
J. Biol. Chem., 286: 38128-35 (2011)  2010

Mostrar resumen
21908604 21908604
Lipocalin-13 regulates glucose metabolism by both insulin-dependent and insulin-independent mechanisms.
Cho, Kae Won, et al.
Mol. Cell. Biol., 31: 450-7 (2011)  2010

Mostrar resumen
21135134 21135134