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MABF1445 Anti-KLRG1 (mouse), violetFluor™ 450, clone 2F1 Antibody

Anti-KLRG1 (mouse), violetFluor™ 450, clone 2F1 Antibody is an antibody against KLRG1 for use in Flow Cytometry.

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Research Category: Inflammation & Immunology Research Sub-Category: Immunoglobulins & Immunology Gene Symbol: Klrg1, Mafa UniProt Number: O88713
MABF1445
100 μg  
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Tabla espec. clave

Species ReactivityKey ApplicationsHostFormatAntibody Type
MFCSHmvioletFluor™ 450Monoclonal Antibody
Description
Catalogue NumberMABF1445
DescriptionAnti-KLRG1 (mouse), violetFluor™ 450, clone 2F1 Antibody
Alternate Names
  • Killer cell lectin-like receptor subfamily G member 1
  • Mast cell function-associated antigen 2F1
  • KLRG1
Background InformationThe 2F1 antibody reacts with mouse KLRG1 (Killer cell Lectin-like Receptor G1). This 30-38 kDa homodimeric receptor may be expressed by activated, mature NK cells and by effector/memory T cells, with potentially different roles in each cell type. KLRG1 can regulate, in an inhibitory fashion, the development and effector functions of NK cells, and is often cited as a senescence or terminal differentiation marker for T cells. Ligands for KLRG1 include members of the cadherin family of adhesion molecules, specifically N-Cadherin, E-Cadherin, and R-Cadherin. These interactions may induce bidirectional, immunosuppressive signaling in both KLRG- and Cadherin-expressing cells. A more recently identified role for KLRG1-Cadherin signaling in tissue organization, e.g. in cardiac angiogenesis, expands the function of these interactions beyond immunosuppression of immune cells. (Bouchentouf et al. 2010. J. Immunol. 185: 7014-7025).
References
Product Information
FormatvioletFluor™ 450
PresentationPurified Golden Syrian Hamster monoclonal containing 10 mM NaH2PO4, 150 mM NaCl, 0.09% NaN3, 0.1% gelatin, pH7.2.
Quality LevelMQ100
Applications
ApplicationAnti-KLRG1 (mouse), violetFluor™ 450, clone 2F1 Antibody is an antibody against KLRG1 for use in Flow Cytometry.
Key Applications
  • Flow Cytometry
Biological Information
ImmunogenImmunogen information for this antibody is proprietary information.
Clone2F1
ConcentrationPlease refer to lot specific datasheet.
HostSyrian Hamster
IsotypeIgG
Species Reactivity
  • Mouse
Antibody TypeMonoclonal Antibody
Gene Symbol
  • Klrg1
  • Mafa
Purification MethodPurified by size-exclusion chromatography
UniProt Number
Physicochemical Information
Dimensions
Materials Information
Toxicological Information
Safety Information according to GHS
Safety Information
Product Usage Statements
Quality AssuranceThis monoclonal antibody was purified from tissue culture supernatant via affinity chromatography. The purified antibody was conjugated under optimal conditions, with unreacted dye removed from the preparation.

Flow Cytometry Analysis: 0.125 μg from a representative lot detected KLRG1 in one million C57Bl/6 splenocytes stained with PE Anti-mouse NK1.1.
Usage Statement
  • Unless otherwise stated in our catalog or other company documentation accompanying the product(s), our products are intended for research use only and are not to be used for any other purpose, which includes but is not limited to, unauthorized commercial uses, in vitro diagnostic uses, ex vivo or in vivo therapeutic uses or any type of consumption or application to humans or animals.
Storage and Shipping Information
Storage ConditionsStable for 1 year at 2-8°C from date of receipt.
Note: It is recommended to store the product undiluted at 2-8°C and protected from prolonged exposure to light. Do not freeze.
Packaging Information
Material Size100 μg
Transport Information
Supplemental Information
Specifications
Global Trade Item Number
Número de referencia GTIN
MABF1445 04055977291674

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Categorías

Life Science Research > Antibodies and Assays > Primary Antibodies