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ABN266 Anti-KIF5A Antibody

Detect the KIF5A protein using this Anti-KIF5A validated for use in WB & ICC.

Anti-KIF5A Antibody: Ficha de datos de seguridad (MSDS o SDS), certificado de análisis y de calidad (CoA y CoQ), expedientes, folletos y otros documentos disponibles.
Research Category: Neuroscience Research Sub-Category: Developmental Neuroscience Gene Symbol: KIF5A UniProt Number: Q12840
ABN266
100 µg  
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Tabla espec. clave

Species ReactivityKey ApplicationsHostFormatAntibody Type
H, MWB, ICCRbAffinity PurifiedPolyclonal Antibody
Description
Catalogue NumberABN266
DescriptionAnti-KIF5A Antibody
Alternate Names
  • Kinesin heavy chain isoform 5
  • neuronal kinesin heavy chain
  • NKHC
Background InformationKinesin heavy chain isoform 5A (KIF5) is a member of the kinesin-like protein family. These proteins are microtubule-dependent motors that slide along microtubules and transport cellular organelles and mRNA to different parts of the cell. In neurons, KIF5A performs this role in an anterograde fashion from the neuronal cell body to axonal or dendritic terminals. KIF5A was initially differentiated from the ubiquitously expressed kinesin as being highly enriched in subsets of neurons and selectively concentrated in the cell body. Mutations in one of the isoforms of KIF5 (KIF5A) is thought to be involved in hereditary spastic paraplegias.
References
Product Information
FormatAffinity Purified
Control
  • Mouse brain nuclear extract
PresentationPurified rabbit polyclonal in buffer containing PBS with 0.02% sodium azide.
Quality LevelMQ100
Applications
ApplicationDetect the KIF5A protein using this Anti-KIF5A validated for use in WB & ICC.
Key Applications
  • Western Blotting
  • Immunocytochemistry
Application NotesImmunocytochemistry Analysis: 5 µg/mL from a representative lot detected KIF5A in K562 cells.
Biological Information
ImmunogenKLH-conjugated linear peptide corresponding to human KIF5A.
ConcentrationPlease refer to the Certificate of Analysis for the lot-specific concentration.
HostRabbit
SpecificityThis antibody can recognize isoforms KIF5A, KIF5B, and KIF5C.
Species Reactivity
  • Human
  • Mouse
Antibody TypePolyclonal Antibody
Gene Symbol
  • KIF5A
Purification MethodAntigen Affinity Purified
UniProt Number
Molecular Weight~117 kDa observed. Uncharacterized bands may appear at ~45 kDa and ~57 kDa in some lysates.
Physicochemical Information
Dimensions
Materials Information
Toxicological Information
Safety Information according to GHS
Safety Information
Product Usage Statements
Quality AssuranceEvaluated by Western Blot in mouse brain nuclear extract.

Western Blot Analysis: 1 µg/mL of this antibody detected KIF5A in 15 µg/mL of mouse brain nuclear extract.
Usage Statement
  • Unless otherwise stated in our catalog or other company documentation accompanying the product(s), our products are intended for research use only and are not to be used for any other purpose, which includes but is not limited to, unauthorized commercial uses, in vitro diagnostic uses, ex vivo or in vivo therapeutic uses or any type of consumption or application to humans or animals.
Storage and Shipping Information
Storage ConditionsStable for 1 year at 2-8°C from date of receipt.
Packaging Information
Material Size100 µg
Transport Information
Supplemental Information
Specifications
Global Trade Item Number
Número de referencia GTIN
ABN266 04053252830952