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MABE441 Anti-HJURP Antibody, clone 144K/B1

Detect Holliday junction recognition protein using this mouse monoclonal antibody, Anti-HJURP Antibody, clone 144K/B1 validated for use in western blotting & IP.

Anti-HJURP Antibody, clone 144K/B1: Ficha de datos de seguridad (MSDS o SDS), certificado de análisis y de calidad (CoA y CoQ), expedientes, folletos y otros documentos disponibles.
Research Category: Epigenetics & Nuclear Function Research Sub-Category: Chromatin Biology Gene Symbol: HJURP, FAKTS, FLEG1, URLC9 UniProt Number: Q8NCD3
MABE441
100 µg  
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Tabla espec. clave

Species ReactivityKey ApplicationsHostFormatAntibody Type
HWB, IP, ChIPMPurifiedMonoclonal Antibody
Description
Catalogue NumberMABE441
DescriptionAnti-HJURP Antibody, clone 144K/B1
Alternate Names
  • Holliday junction recognition protein
  • 14-3-3-associated AKT substrate
  • Fetal liver-expressing gene 1 protein
  • Up-regulated in lung cancer 9
  • HJURP
Background InformationHolliday junction recognition protein (HJURP) is also known as 14-3-3-associated AKT substrate (FAKTS), Fetal liver-expressing gene 1 protein (FLEG1) and Up-regulated in lung cancer 9 (URLC9). HJURP is a centromeric protein that acts as a specific chaperone for CENPA and is required for the incorporation of newly synthesized CENPA molecules into nucleosomes at replicated centromeres. HJURP is highly expressed in the thymus, testis, and in many lung cancer samples with lower levels found in placenta, small intestine, liver, skeletal muscle, and colon.
References
Product Information
FormatPurified
Control
  • HEK293 cell lysate
PresentationPurified mouse monoclonal IgG2bκ in buffer containing 0.1 M Tris-Glycine (pH 7.4), 150 mM NaCl with 0.05% sodium azide.
Quality LevelMQ100
Applications
ApplicationDetect Holliday junction recognition protein using this mouse monoclonal antibody, Anti-HJURP Antibody, clone 144K/B1 validated for use in western blotting & IP.
Key Applications
  • Western Blotting
  • Immunoprecipitation
  • Chromatin Immunoprecipitation (ChIP)
Application NotesImmunoprecipitation Analysis: A representative lot immunoprecipitated HJURP in HeLa nuclear extract (CNIO, Madrid, Spain).

Chromatin Immunoprecipitation (ChIP) Analysis: A representative lot immmunoprecipitated HJURP in HEK293 cell lysate (CNIO, Madrid, Spain).
Biological Information
ImmunogenRecombinant protein corresponding to human HJURP.
Clone144K/B1
ConcentrationPlease refer to the Certificate of Analysis for the lot-specific concentration.
HostMouse
IsotypeIgG2bκ
Species Reactivity
  • Human
Antibody TypeMonoclonal Antibody
Entrez Gene Number
Gene Symbol
  • HJURP
  • FAKTS
  • FLEG1
  • URLC9
Purification MethodProtein G Purified
UniProt Number
Molecular Weight~90 kDa observed
Physicochemical Information
Dimensions
Materials Information
Toxicological Information
Safety Information according to GHS
Safety Information
Product Usage Statements
Quality AssuranceEvaluated by Western Blotting in HEK293 cell lysate.

Western Blotting Analysis: 0.5 µg/mL of this antibody detected HJURP in 10 µg of HEK293 cell lysate.
Usage Statement
  • Unless otherwise stated in our catalog or other company documentation accompanying the product(s), our products are intended for research use only and are not to be used for any other purpose, which includes but is not limited to, unauthorized commercial uses, in vitro diagnostic uses, ex vivo or in vivo therapeutic uses or any type of consumption or application to humans or animals.
Storage and Shipping Information
Storage ConditionsStable for 1 year at 2-8°C from date of receipt.
Packaging Information
Material Size100 µg
Transport Information
Supplemental Information
Specifications
Global Trade Item Number
Número de referencia GTIN
MABE441 04053252882913