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ABC430 Anti-FABP1 Antibody

ABC430
100 µg  
Purchase on Sigma-Aldrich

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Descripción

Replacement Information

Ofertas especiales

Tabla espec. clave

Species ReactivityKey ApplicationsHostFormatAntibody Type
H, RWB, IHCRbAffinity PurifiedPolyclonal Antibody
Description
Catalogue NumberABC430
DescriptionAnti-FABP1 Antibody
Alternate Names
  • Fatty acid-binding protein, liver
  • Fatty acid-binding protein 1
  • Liver-type fatty acid-binding protein
  • L-FABP
  • Squalene- and sterol-carrier protein
  • SCP
  • Z-protein
  • p14
Background InformationFABP1, also known as Fatty acid-binding protein, Liver Fatty acid-binding protein, Fatty acid-binding protein 1, Liver-type fatty acid-binding protein, L-FABP, Squalene- and sterol-carrier protein, SCP, Z-protein, or p14, and encoded by the gene FABP1/FABPL, is an important fatty acid binding and transport protein. FABP1 is produced in the liver and is part of a family of lipid carrier proteins. FABP1 facilitate the transfer of fatty acids between extra and intracellular membranes. FABP1 level in the blood is used as a biomarker for obesity and type II diabetes. Additionally, recent research indicates that FABP1 can modulate stellate cell activation and this may lead to diet-induced nonalcoholic fatty liver disease, thus FABP1 is a key focus of metabolic research.
References
Product Information
FormatAffinity Purified
PresentationPurified rabbit polyclonal in buffer containing 0.1 M Tris-Glycine (pH 7.4), 150 mM NaCl with 0.05% sodium azide.
Quality LevelMQ100
Applications
ApplicationThis Anti-FABP1 Antibody is validated for use in Western Blotting and Immunohistochemistry for the detection of FABP1.
Key Applications
  • Western Blotting
  • Immunohistochemistry
Application NotesImmunohistochemistry Analysis: A 1:2,000 dilution from a representative lot detected FABP1 in rat liver tissue.
Biological Information
ImmunogenKLH-conjugated linear peptide corresponding to human FABP1 near the N-terminus.
EpitopeNear N-terminus
ConcentrationPlease refer to lot specific datasheet.
HostRabbit
Species Reactivity
  • Human
  • Rat
Species Reactivity NoteHuman, Rat. Predicted to react with Primate based on 100% sequence homology. Other homologies: Mouse (94% sequence homology).
Antibody TypePolyclonal Antibody
Entrez Gene Number
Gene Symbol
  • FABP1
  • FABPL
Purification MethodAffinity Purfied
UniProt Number
Molecular Weight~14 kDa observed
Physicochemical Information
Dimensions
Materials Information
Toxicological Information
Safety Information according to GHS
Safety Information
Product Usage Statements
Quality AssuranceEvaluated by Western Blotting in HepG2 cell lysate.

Western Blotting Analysis: 2.0 µg/mL of this antibody detected FABP1 in 10 µg of HepG2 cell lysate.
Usage Statement
  • Unless otherwise stated in our catalog or other company documentation accompanying the product(s), our products are intended for research use only and are not to be used for any other purpose, which includes but is not limited to, unauthorized commercial uses, in vitro diagnostic uses, ex vivo or in vivo therapeutic uses or any type of consumption or application to humans or animals.
Storage and Shipping Information
Storage ConditionsStable for 1 year at 2-8°C from date of receipt.
Packaging Information
Material Size100 µg
Transport Information
Supplemental Information
Specifications
Global Trade Item Number
Número de referencia GTIN
ABC430 04053252981814