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MAB4356A4 Anti-DPPA-2 Antibody, clone 6C1.2, Alexa Fluor® 488 conjugate

MAB4356A4
100 µL  
Purchase on Sigma-Aldrich

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Tabla espec. clave

Species ReactivityKey ApplicationsHostFormatAntibody Type
MICCMAlexaFluor®488Monoclonal Antibody
Description
Catalogue NumberMAB4356A4
DescriptionAnti-DPPA-2 Antibody, clone 6C1.2, Alexa Fluor® 488 conjugate
Alternate Names
  • Pluripotent embryonic stem cell-related gene 1 protein
  • developmental pluripotency associated 2
Background InformationDPPA-2 (developmental pluripotency associated-2) is a novel Oct-4-related protein that is localized to the nucleus of mouse fetal germ cells. DPPA-2 has binding sites for both POU and Sox-2 protein domains and is expressed primarily in the developing germ line following gastrulation. These associations suggest that this protein participates in a very strong supportive role in maintaining cell pluripotentiality. In addition to its role as a pluripotency marker, more recent research using cancer cells suggests that DPPA-2 may also act as an embryo-cancer antigen—pointing to the presence of abnormal cell growth and the formation of cancerous cells.
References
Product Information
FormatAlexaFluor®488
Control
  • Mouse Embryonic Stem Cells (SCR012).
PresentationPurified mouse monoclonal IgG2aλ supernatant in buffer containing 0.1 M Tris-Glycine (pH 7.4), 150 mM NaCl with 0.05% sodium azide.
Quality LevelMQ100
Applications
ApplicationThis Anti-DPPA-2 Antibody, clone 6C1.2, Alexa Fluor 488 conjugate is validated for use in ICC for the detection of DPPA-2.
Key Applications
  • Immunocytochemistry
Biological Information
Immunogenrecombinant protein corresponding to mouse DPPA-2.
Clone6C1.2
ConcentrationPlease refer to the Certificate of Analysis for the lot-specific concentration.
HostMouse
Species Reactivity
  • Mouse
Antibody TypeMonoclonal Antibody
Entrez Gene Number
Gene Symbol
  • PESCRG1
Purification MethodProtein G Purified
UniProt Number
Molecular Weight~30 kDa observed
Physicochemical Information
Dimensions
Materials Information
Toxicological Information
Safety Information according to GHS
Safety Information
Product Usage Statements
Quality AssuranceEvaluated by Immunocytochemistry in Mouse Embryonic Stem Cells (SCR012). Immunocytochemsitry Analysis: A 1:100 dilution of this antibody detected SOX-2 in Mouse Embryonic Stem Cells (SCR012).
Usage Statement
  • Unless otherwise stated in our catalog or other company documentation accompanying the product(s), our products are intended for research use only and are not to be used for any other purpose, which includes but is not limited to, unauthorized commercial uses, in vitro diagnostic uses, ex vivo or in vivo therapeutic uses or any type of consumption or application to humans or animals.
Storage and Shipping Information
Storage ConditionsMaintain refrigerated at 2-8ºC protected from light in undiluted aliquots for up to 6 months from date of receipt.
Packaging Information
Material Size100 µL
Transport Information
Supplemental Information
Specifications
Global Trade Item Number
Número de referencia GTIN
MAB4356A4 04053252599699