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MABF1461 Anti-CD62L (L-Selectin) (mouse), redFluor™ 710, clone MEL-14 Antibody

Anti-CD62L (L-Selectin) (mouse), redFluor™ 710, clone MEL-14 Antibody is an antibody against CD62L for use in Flow Cytometry.

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Research Category: Inflammation & Immunology Research Sub-Category: Immunoglobulins & Immunology Gene Symbol: Sell, Lnhr, Ly-22, Ly22 UniProt Number: P18337
MABF1461
100 μg  
Purchase on Sigma-Aldrich

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Tabla espec. clave

Species ReactivityKey ApplicationsHostFormatAntibody Type
MFCRredFluor™ 710Monoclonal Antibody
Description
Catalogue NumberMABF1461
DescriptionAnti-CD62L (L-Selectin) (mouse), redFluor™ 710, clone MEL-14 Antibody
Alternate Names
  • L-selectin
  • CD62 antigen-like family member L
  • Leukocyte adhesion molecule 1 (LAM-1)
  • Leukocyte-endothelial cell adhesion molecule 1 (LECAM1)
  • Lymph node homing receptor
  • Lymphocyte antigen 22 (Ly-22)
  • Lymphocyte surface MEL-14 antigen
  • CD62L
  • CD62L (L-Selectin)
Background InformationThe MEL-14 antibody is specific for mouse CD62L, also known as L-Selectin, a cell adhesion molecule which facilitates lymphocyte “rolling” on activated vascular endothelium and homing to high endothelial venules (HEV) as immune cells transmigrate from blood into peripheral tissues. L-Selectin is a member of a family of Selectin molecules which act together with the integrin family of adhesion molecules to mediate leukocyte-endothelial interactions. L-Selectin is characteristically expressed by neutrophils, and is also found on B cells, monocytes, granulocytes, and at varying levels on naive, effector and memory T cells. It is rapidly shed upon cell activation, releasing into the circulation a soluble form whose biological role is of particular interest in cancer biology research.The MEL-14 antibody may be used as a phenotypic marker for CD62L expression on a variety of immune cell types. Please note that CD62L (L-Selectin) itself is also referred to as MEL-14 in the literature.
References
Product Information
FormatredFluor™ 710
PresentationPurified Rat monoclonal containing 10 mM NaH2PO4, 150 mM NaCl, 0.09% NaN3, 0.1% gelatin, pH7.2.
Quality LevelMQ100
Applications
ApplicationAnti-CD62L (L-Selectin) (mouse), redFluor™ 710, clone MEL-14 Antibody is an antibody against CD62L for use in Flow Cytometry.
Key Applications
  • Flow Cytometry
Biological Information
ImmunogenImmunogen information for this antibody is proprietary information.
CloneMEL-14
ConcentrationPlease refer to lot specific datasheet.
HostRat
Species Reactivity
  • Mouse
Antibody TypeMonoclonal Antibody
Gene Symbol
  • Sell
  • Lnhr
  • Ly-22
  • Ly22
Purification MethodPurified by size-exclusion chromatography
UniProt Number
Physicochemical Information
Dimensions
Materials Information
Toxicological Information
Safety Information according to GHS
Safety Information
Product Usage Statements
Quality AssuranceThis monoclonal antibody was purified from tissue culture supernatant via affinity chromatography. The purified antibody was conjugated under optimal conditions, with unreacted dye removed from the preparation.

Flow Cytometry Analysis: 0.5 μg from a representative lot detected CD62L (L-Selectin) in one million C57Bl/6 splenocytes.
Usage Statement
  • Unless otherwise stated in our catalog or other company documentation accompanying the product(s), our products are intended for research use only and are not to be used for any other purpose, which includes but is not limited to, unauthorized commercial uses, in vitro diagnostic uses, ex vivo or in vivo therapeutic uses or any type of consumption or application to humans or animals.
Storage and Shipping Information
Storage ConditionsStable for 1 year at 2-8°C from date of receipt.
Note: It is recommended to store the product undiluted at 2-8°C and protected from prolonged exposure to light. Do not freeze.
Packaging Information
Material Size100 μg
Transport Information
Supplemental Information
Specifications
Global Trade Item Number
Número de referencia GTIN
MABF1461 04055977291810

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Categorías

Life Science Research > Antibodies and Assays > Primary Antibodies