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MABF717 Anti-CD62L (L-Selectin) Antibody (mouse), PE-Cy7, clone MEL-14

This rat monoclonal antibody Anti-CD62L (L-Selectin) (mouse), PE-Cy7, clone MEL-14 validated for use in IP, IHC & Flow Cytometry for the detection of CD62L (L-Selectin).

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Research Category: Inflammation & Immunology Gene Symbol: Sell, Lnhr, Ly-22, Ly22 UniProt Number: P18337
MABF717
25 µg  
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Tabla espec. clave

Species ReactivityKey ApplicationsHostFormatAntibody Type
MIP, IHC, FCRPE-Cy7Monoclonal Antibody
Description
Catalogue NumberMABF717
DescriptionAnti-CD62L (L-Selectin) Antibody (mouse), PE-Cy7, clone MEL-14
Alternate Names
  • L-selectin
  • CD62 antigen-like family member L
  • Leukocyte adhesion molecule 1
  • LAM-1
  • Leukocyte-endothelial cell adhesion molecule 1
  • LECAM1
  • Lymph node homing receptor
  • Lymphocyte antigen 22
  • Ly-22
  • Lymphocyte surface MEL-14 antigen
  • CD62L
Background InformationThe MEL-14 antibody is specific for mouse CD62L, also known as L-Selectin, a cell adhesion molecule which facilitates lymphocyte “rolling” on activated vascular endothelium and homing to high endothelial venules (HEV) as immune cells transmigrate from blood into peripheral tissues. L-Selectin is a member of a family of Selectin molecules which act together with the integrin family of adhesion molecules to mediate leukocyte-endothelial interactions. L-Selectin is characteristically expressed by neutrophils, and is also found on B cells, monocytes, granulocytes, and at varying levels on naive, effector and memory T cells. It is rapidly shed upon cell activation, releasing into the circulation a soluble form whose biological role is of particular interest in cancer biology research.The MEL-14 antibody may be used as a phenotypic marker for CD62L expression on a variety of immune cell types. Please note that CD62L (L-Selectin) itself is also referred to as MEL-14 in the literature.
References
Product Information
FormatPE-Cy7
PresentationPurified Rat Monoclonal Antibody in buffer containing 10 mM NaH2PO4, 150 mM NaCl, 0.1% gelatin, pH 7.2, and up to 0.1% sodium azide.
Quality LevelMQ100
Applications
ApplicationThis rat monoclonal antibody Anti-CD62L (L-Selectin) (mouse), PE-Cy7, clone MEL-14 validated for use in IP, IHC & Flow Cytometry for the detection of CD62L (L-Selectin).
Key Applications
  • Immunoprecipitation
  • Immunohistochemistry
  • Flow Cytometry
Biological Information
ImmunogenImmunogen information for this antibody is proprietary information.
CloneMEL-14
Concentration0.2 mg/mL
HostRat
IsotypeIgG2aκ
Species Reactivity
  • Mouse
Antibody TypeMonoclonal Antibody
Gene Symbol
  • Sell
  • Lnhr
  • Ly-22
  • Ly22
Purification MethodSize Exclusion Chromatography
UniProt Number
Physicochemical Information
Dimensions
Materials Information
Toxicological Information
Safety Information according to GHS
Safety Information
Product Usage Statements
Quality AssuranceThe monoclonal antibody was purified from tissue culture supernatant via affinity chromatography. The purified antibody was conjugated under optimal conditions, with unreacted dye removed from the preparation.

Flow Cytometry Analysis: 0.06 µg of this antibody detected CD62L (L-Selectin) in one million C57Bl/6 splenocytes.
Usage Statement
  • Unless otherwise stated in our catalog or other company documentation accompanying the product(s), our products are intended for research use only and are not to be used for any other purpose, which includes but is not limited to, unauthorized commercial uses, in vitro diagnostic uses, ex vivo or in vivo therapeutic uses or any type of consumption or application to humans or animals.
Storage and Shipping Information
Storage ConditionsIt is recommended to store the product undiluted at 2-8°C and protected from prolonged exposure to light. Do not freeze.
Packaging Information
Material Size25 µg
Transport Information
Supplemental Information
Specifications
Global Trade Item Number
Número de referencia GTIN
MABF717 04053252965821

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Categorías

Life Science Research > Antibodies and Assays > Primary Antibodies