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ABD134 Anti-BMP Antibody15

ABD134
100 µg  
Purchase on Sigma-Aldrich

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Descripción

Replacement Information

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Tabla espec. clave

Species ReactivityKey ApplicationsHostFormatAntibody Type
MWB, ICCRbAffinity PurifiedPolyclonal Antibody
Description
Catalogue NumberABD134
DescriptionAnti-BMP Antibody15
Alternate Names
  • Bone morphogenetic protein 15
  • BMP-15
  • Growth/differentiation factor 9B
  • GDF9B
  • GDF-9B
  • ODG2
  • POF4
Background InformationBone morphogenetic protein 15 (BMP15), also known as Growth/differentiation factor 9B (GDF9B), is part of the transforming growth factor-beta (TGF-β) superfamily. BMP15 is an oocyte-specific growth and differentiation factor that stimulates folliculogenesis and development as well as granulosa cell (GC) growth. BMP15 is expressed exclusively in the oocyte. BMP15 defects are linked to ovarian dysgenesis type 2 (ODG2) and premature ovarian failure type 4 (POF4). Potentially, BMP15 could be an oogenesis marker, used to monitor the differentiation of human amniotic fluid stem cells into oocyte-like cells.
References
Product Information
FormatAffinity Purified
Control
  • NIH/3T3 cell lysate
PresentationPurified rabbit polyclonal in buffer containing PBS with up to 0.1% sodium azide.
Quality LevelMQ100
Applications
ApplicationAnti-BMP Antibody15 is a highly specific rabbit polyclonal antibody, that targets BMP & has been tested in western blotting & ICC.
Key Applications
  • Western Blotting
  • Immunocytochemistry
Application NotesImmunocytochemistry Analysis: 2.5 µg/mL from a representative lot detected BMP15 in NIH/3T3 cells.
Biological Information
ImmunogenKLH-conjugated linear peptide corresponding to human BMP15.
ConcentrationPlease refer to the Certificate of Analysis for the lot-specific concentration.
HostRabbit
Species Reactivity
  • Mouse
Species Reactivity NoteDemonstrated to react with Mouse. Predicted to react with Human based on immunogen design.
Antibody TypePolyclonal Antibody
Gene Symbol
  • BMP15
Purification MethodAntigen Affinity Purified
UniProt Number
Molecular Weight~53 kDa observed. Uncharacterized bands may appear in some lysate(s).
Physicochemical Information
Dimensions
Materials Information
Toxicological Information
Safety Information according to GHS
Safety Information
Product Usage Statements
Quality AssuranceEvaluated by Western Blotting in NIH/3T3 cell lysate.

Western Blotting Analysis: 1 µg/mL of this antibody detected BMP15 in 15 µg of NIH/3T3 cell lysate.
Usage Statement
  • Unless otherwise stated in our catalog or other company documentation accompanying the product(s), our products are intended for research use only and are not to be used for any other purpose, which includes but is not limited to, unauthorized commercial uses, in vitro diagnostic uses, ex vivo or in vivo therapeutic uses or any type of consumption or application to humans or animals.
Storage and Shipping Information
Storage ConditionsStable for 1 year at 2-8°C from date of receipt.
Packaging Information
Material Size100 µg
Transport Information
Supplemental Information
Specifications
Global Trade Item Number
Número de referencia GTIN
ABD134 04053252906954