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MABN317 Anti-BM88/Cend1 Antibody, clone 4A3.1

Anti-BM88/Cend1 Antibody, clone 4A3.1 is an antibody against BM88/Cend1 for use in western blotting & IHC.

Anti-BM88/Cend1 Antibody, clone 4A3.1: Ficha de datos de seguridad (MSDS o SDS), certificado de análisis y de calidad (CoA y CoQ), expedientes, folletos y otros documentos disponibles.
Research Category: Neuroscience Research Sub-Category: Developmental Signaling Gene Symbol: CEND1, BM88 UniProt Number: Q8N111
MABN317
100 µg  
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Tabla espec. clave

Species ReactivityKey ApplicationsHostFormatAntibody Type
HWB, IHCMPurifiedMonoclonal Antibody
Description
Catalogue NumberMABN317
DescriptionAnti-BM88/Cend1 Antibody, clone 4A3.1
Alternate Names
  • Cell cycle exit and neuronal differentiation protein 1
  • BM88 antigen
Background InformationBM88/Cend1, also known as Cell cycle exit and neuronal differentiation protein 1, or BM88 antigen, and encoded by the gene Cend1/BM88, is a neuronal specific membrane protein that is involved in neuronal development. BM88/Cend1 is particularly important in cerebellar development including Purkinje cell differentiation as well as radial glia guided migration of cerebellar granule cell development. Overexpression of BM88/CEND1 in transplanted neural stem cells also appears to enhance the regeneration of neuronal cells in injured rodent brains. BM88/Cend1 function is at least partially mediated through interacting with the important developmental protein Ahi1, and research indicates that BM88/Cend1 is also involved in Ahi1-associated hypothalamic neuronal differentiation in early development.
References
Product Information
FormatPurified
PresentationPurified mouse monoclonal IgG1κ in buffer containing 0.1 M Tris-Glycine (pH 7.4), 150 mM NaCl with 0.05% sodium azide.
Quality LevelMQ100
Applications
ApplicationAnti-BM88/Cend1 Antibody, clone 4A3.1 is an antibody against BM88/Cend1 for use in western blotting & IHC.
Key Applications
  • Western Blotting
  • Immunohistochemistry
Application NotesImmunohistochemistry Analysis: A 1:50-2,000 dilution from a representative lot detected BM88/Cend1 in human cerebellum, human thalamus sections, and rat cerebral cortex tissue.
Biological Information
ImmunogenGST-tagged recombinant protein corresponding to the cytoplasmic domain of human BM88/Cend1.
EpitopeCytoplasmic domain
Clone4A3.1
Concentration1 mg/mL
HostMouse
IsotypeIgG1κ
Species Reactivity
  • Human
Antibody TypeMonoclonal Antibody
Entrez Gene Number
Gene Symbol
  • CEND1
  • BM88
Purification MethodProtein G Purified
UniProt Number
Molecular Weight~19 kDa observed
Physicochemical Information
Dimensions
Materials Information
Toxicological Information
Safety Information according to GHS
Safety Information
Product Usage Statements
Quality AssuranceEvaluated by Western Blotting in human cortex tissue lysate.

Western Blotting Analysis: 0.5 µg/mL of this antibody detected BM88/Cend1 in 10 µg of human cortex tissue lysate.
Usage Statement
  • Unless otherwise stated in our catalog or other company documentation accompanying the product(s), our products are intended for research use only and are not to be used for any other purpose, which includes but is not limited to, unauthorized commercial uses, in vitro diagnostic uses, ex vivo or in vivo therapeutic uses or any type of consumption or application to humans or animals.
Storage and Shipping Information
Storage ConditionsStable for 1 year at 2-8°C from date of receipt.
Packaging Information
Material Size100 µg
Transport Information
Supplemental Information
Specifications
Global Trade Item Number
Número de referencia GTIN
MABN317 04053252973932