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MABS817 Anti-AGT, clone 1B1 Antibody

Detect AGT using this Anti-AGT, clone 1B1 Antibody validated for use in Western Blotting.

Anti-AGT, clone 1B1 Antibody: Ficha de datos de seguridad (MSDS o SDS), certificado de análisis y de calidad (CoA y CoQ), expedientes, folletos y otros documentos disponibles.
Research Category: Signaling Research Sub-Category: Developmental Signaling Gene Symbol: AGT, SERPINA8 UniProt Number: P01019
MABS817
100 µL  
Purchase on Sigma-Aldrich

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Tabla espec. clave

Species ReactivityKey ApplicationsHostFormatAntibody Type
HWBMAscitesMonoclonal Antibody
Description
Catalogue NumberMABS817
ReplacesMABC123
DescriptionAnti-AGT, clone 1B1 Antibody
Alternate Names
  • Angiotensinogen
  • Serpin A8 -angiotensin II
  • Angiotensin-4
  • Angiotensin 3-8
  • Angiotensin IV
  • Ang IV
  • Angiotensin 1-9
  • Angiotensin 1-7
  • Angiotensin 1-5
  • Angiotensin 1-4
  • AGT
Background InformationAngiotensinogen (AGT) is expressed in the liver and is cleaved by the enzyme renin in response to lowered blood pressure. The resulting product, angiotensin I, is then cleaved by angiotensin converting enzyme (ACE) to generate the physiologically active enzyme angiotensin II. The protein is involved in maintaining blood pressure and in the pathogenesis of essential hypertension and preeclampsia. Mutations in this gene are associated with susceptibility to essential hypertension, and can cause renal tubular dysgenesis, a severe disorder of renal tubular development. Defects in this gene have also been associated with non-familial structural atrial fibrillation, and inflammatory bowel disease.
References
Product Information
FormatAscites
PresentationMouse monoclonal IgG2bascitic fluid containing 0.03% sodium azide.
Quality LevelMQ300
Applications
ApplicationDetect AGT using this Anti-AGT, clone 1B1 Antibody validated for use in Western Blotting.
Key Applications
  • Western Blotting
Biological Information
ImmunogenPurified recombinant fragment of human AGT expressed in E. Coli.
Clone1B1
ConcentrationPlease refer to lot specific datasheet.
HostMouse
IsotypeIgG2b
Species Reactivity
  • Human
Antibody TypeMonoclonal Antibody
Gene Symbol
  • AGT
  • SERPINA8
Purification MethodUnpurified
UniProt Number
Molecular Weight~53 kDa observed. Uncharacterized bands may be observed in some lysate(s).
Physicochemical Information
Dimensions
Materials Information
Toxicological Information
Safety Information according to GHS
Safety Information
Product Usage Statements
Quality AssuranceEvaluated by Western Blotting in human plasma.

Western Blotting Analysis (WB): A 1:500-2,000 dilution of this antibody detected AGT in human plasma.
Usage Statement
  • Unless otherwise stated in our catalog or other company documentation accompanying the product(s), our products are intended for research use only and are not to be used for any other purpose, which includes but is not limited to, unauthorized commercial uses, in vitro diagnostic uses, ex vivo or in vivo therapeutic uses or any type of consumption or application to humans or animals.
Storage and Shipping Information
Storage ConditionsStable for 1 year at -20°C from date of receipt.
Handling Recommendations: Upon receipt and prior to removing the cap, centrifuge the vial and gently mix the solution. Aliquot into microcentrifuge tubes and store at -20°C. Avoid repeated freeze/thaw cycles, which may damage IgG and affect product performance.
Packaging Information
Material Size100 µL
Transport Information
Supplemental Information
Specifications
Global Trade Item Number
Número de referencia GTIN
MABS817 04055977172355

Documentation

Anti-AGT, clone 1B1 Antibody Ficha datos de seguridad (MSDS)

Título

Ficha técnica de seguridad del material (MSDS) 

Anti-AGT, clone 1B1 Antibody Certificados de análisis

CargoNúmero de lote
Anti-AGT, clone 1B1 - VP2110250 VP2110250
Anti-AGT, clone 1B1 -QVP1502057 QVP1502057

Licencias necesarias e Información técnica

Cargo
Characterization of Estrogen Receptor α Phosphorylation Sites in Breast Cancer Tissue Using the SNAP i.d® 2.0 System
White Paper: Further considerations of antibody validation and usage.