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119135 Adenosine A1 Receptor Agonist I, CPA - CAS 41552-82-3 - Calbiochem

Ficha de datos de seguridad (MSDS o SDS), certificado de análisis y de calidad (CoA y CoQ), expedientes, folletos y otros documentos disponibles.

Sinónimos: (2R,3R,4S,5R)-2-(6-(cyclopentylamino)-9H-purin-9-yl)-5-(hydroxymethyl)tetrahydrofuran-3,4-diol, N6-Cyclopentyl-adenosine

119135
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Descripción

Replacement Information

Products

Número de referenciaEmbalaje Cant./Env.
119135-25MG Frasco de vidrio 25 mg
Description
OverviewA potent and selective agonist of adenosine A1 receptor (A1R) (Ki = 2.3 nM, 790 nM, 18.6 µM, 43nM for human A1, A2A, A2B, and A3, respectively).
Catalogue Number119135
Brand Family Calbiochem®
Synonyms(2R,3R,4S,5R)-2-(6-(cyclopentylamino)-9H-purin-9-yl)-5-(hydroxymethyl)tetrahydrofuran-3,4-diol, N6-Cyclopentyl-adenosine
References
ReferencesMigita, H., et al. 2008. J Neurosci Res. 86, 2820.
Burgdorf, C. et al. 2005. J Cardiovasc Pharmacol. 45, 1.
Klotz, K. N., et al. 2000. Naunyn Schmiedebergs Arch Pharmacol. 362, 382.
Mironov, S., et al. 1990. J Neurophysiol. 81, 1.
Monopoli, A., et al. 1994. Arzneimittelforschung. 44, 1305.
Concas, A., et al. 1993. J Pharmacol Exp Ther. 267, 844.
Lohse, M. J., et al. 1988. Nauryn Schmiedebergs Arch Pharmacol. 337, 687.
Coffin, V. L., et al. 1987. J Pharmacol Exp Ther. 241, 76.
Product Information
CAS number41552-82-3
FormWhite solid
Hill FormulaC₁₅H₂₁N₅O₄
Chemical formulaC₁₅H₂₁N₅O₄
ReversibleY
Structure formula ImageStructure formula Image
Quality LevelMQ100
Applications
Biological Information
Primary TargetA1
Primary Target K<sub>i</sub>0.8 nM
Purity≥99% by HPLC
Physicochemical Information
Dimensions
Materials Information
Toxicological Information
Safety Information according to GHS
Safety Information
Product Usage Statements
Storage and Shipping Information
Ship Code Shipped at Ambient Temperature or with Blue Ice or with Dry Ice
Toxicity Standard Handling
Storage +2°C to +8°C
Protect from Light Protect from light
Do not freeze Ok to freeze
Special InstructionsFollowing reconstitution, aliquot and freeze (-20°C). Stock solutions are stable for up to 3 months at -20°C.
Packaging Information
Packaged under inert gas Packaged under inert gas
Transport Information
Supplemental Information
Specifications
Global Trade Item Number
Número de referencia GTIN
119135-25MG 04055977223316

Documentation

Adenosine A1 Receptor Agonist I, CPA - CAS 41552-82-3 - Calbiochem Ficha datos de seguridad (MSDS)

Título

Ficha técnica de seguridad del material (MSDS) 

Adenosine A1 Receptor Agonist I, CPA - CAS 41552-82-3 - Calbiochem Certificados de análisis

CargoNúmero de lote
119135

Referencias bibliográficas

Visión general referencias
Migita, H., et al. 2008. J Neurosci Res. 86, 2820.
Burgdorf, C. et al. 2005. J Cardiovasc Pharmacol. 45, 1.
Klotz, K. N., et al. 2000. Naunyn Schmiedebergs Arch Pharmacol. 362, 382.
Mironov, S., et al. 1990. J Neurophysiol. 81, 1.
Monopoli, A., et al. 1994. Arzneimittelforschung. 44, 1305.
Concas, A., et al. 1993. J Pharmacol Exp Ther. 267, 844.
Lohse, M. J., et al. 1988. Nauryn Schmiedebergs Arch Pharmacol. 337, 687.
Coffin, V. L., et al. 1987. J Pharmacol Exp Ther. 241, 76.
Ficha técnica

Note that this data sheet is not lot-specific and is representative of the current specifications for this product. Please consult the vial label and the certificate of analysis for information on specific lots. Also note that shipping conditions may differ from storage conditions.

Revision28-March-2013 JSW
Synonyms(2R,3R,4S,5R)-2-(6-(cyclopentylamino)-9H-purin-9-yl)-5-(hydroxymethyl)tetrahydrofuran-3,4-diol, N6-Cyclopentyl-adenosine
DescriptionA potent and selective agonist of adenosine A1 receptor (A1R) (Ki = 2.3 nM, 790 nM, 18.6 µM, 43nM for human A1, A2A, A2B, and A3, respectively).
FormWhite solid
Intert gas (Yes/No) Packaged under inert gas
CAS number41552-82-3
Chemical formulaC₁₅H₂₁N₅O₄
Structure formulaStructure formula
Purity≥99% by HPLC
SolubilityDMSO (100 mM), 1N HCl (100 mM), or Ethanol (25 mM; slight warming is required for complete solubilization in ethanol)
Storage Protect from light
+2°C to +8°C
Do Not Freeze Ok to freeze
Special InstructionsFollowing reconstitution, aliquot and freeze (-20°C). Stock solutions are stable for up to 3 months at -20°C.
Toxicity Standard Handling
ReferencesMigita, H., et al. 2008. J Neurosci Res. 86, 2820.
Burgdorf, C. et al. 2005. J Cardiovasc Pharmacol. 45, 1.
Klotz, K. N., et al. 2000. Naunyn Schmiedebergs Arch Pharmacol. 362, 382.
Mironov, S., et al. 1990. J Neurophysiol. 81, 1.
Monopoli, A., et al. 1994. Arzneimittelforschung. 44, 1305.
Concas, A., et al. 1993. J Pharmacol Exp Ther. 267, 844.
Lohse, M. J., et al. 1988. Nauryn Schmiedebergs Arch Pharmacol. 337, 687.
Coffin, V. L., et al. 1987. J Pharmacol Exp Ther. 241, 76.