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532586 AEBSF, HCl ≥99% by HPLC - CAS 30827-99-7 - Calbiochem

AEBSF >99%; 30827-99-7

Ficha de datos de seguridad (MSDS o SDS), certificado de análisis y de calidad (CoA y CoQ), expedientes, folletos y otros documentos disponibles.

Sinónimos: 4-(2-Aminoethyl)benzenesulfonylfluoride, HCl, 4-(2-Aminoethyl)benzene-1-sulfonyl fluoride, HCl

Primary Target: Serine proteases
532586
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Descripción

Replacement Information

Tabla espec. clave

CAS #Empirical Formula
30827-99-7C₈H₁₀FNO₂S·HCl

Products

Número de referenciaEmbalaje Cant./Env.
5325860001 Frasco de vidrio 250 mg
Description
OverviewSpecific irreversible inhibitor of serine proteases. Reacts covalently with a serine at the active site. Inhibits chymotrypsin, kallikrein, plasmin, thrombin, trypsin, and related thrombolytic enzymes. Stable, nontoxic alternative to PMSF (Cat. No. 52332) and DFP (Cat. No. 30967). Used at the same molar concentration (0.1-1.0 mM) as PMSF for most applications. Exhibits low inhibitory activity towards proteinase K. A material with ≥97% purity by HPLC (Cat. No. 101500) & its InSolution™ is also available (Cat. No. 508436).

Please note that the molecular weight for this compound is batch-specific due to variable water content.
Catalogue Number532586
Brand Family Calbiochem®
Synonyms4-(2-Aminoethyl)benzenesulfonylfluoride, HCl, 4-(2-Aminoethyl)benzene-1-sulfonyl fluoride, HCl
References
ReferencesCitron, M., et al. 1996. Neuron 17, 171.
Ohkubo, I., et al. 1994. J. Biochem. 116, 1182.
Mintz, G.R. 1993. BioPharm. 6, 34.
Lawson, W.B., et al. 1982. Folia Haematol. 109, 52.
Markwardt, F., et al. 1974. Biochem. Pharmacol. 23, 2247.
Markwardt, F., et al. 1973. Thromb. Res. 2, 343.
Baker, B.R., and Cory, M. 1971. 14, 119.
Product Information
CAS number30827-99-7
FormWhite powder
Hill FormulaC₈H₁₀FNO₂S·HCl
Chemical formulaC₈H₁₀FNO₂S·HCl
ReversibleN
Quality LevelMQ100
Applications
Biological Information
Primary TargetSerine proteases
Purity≥99% by HPLC
Physicochemical Information
Dimensions
Materials Information
Toxicological Information
Safety Information according to GHS
Safety Information
R PhraseR: 34

Causes burns.
S PhraseS: 22-36/37/39-45

Do not breathe dust.
Wear suitable protective clothing, gloves and eye/face protection.
In case of accident or if you feel unwell, seek medical advice immediately (show the label where possible).
Product Usage Statements
Storage and Shipping Information
Ship Code Ambient Temperature Only
Toxicity Corrosive
Storage +2°C to +8°C
Protect from Light Protect from light
Protect from Moisture Protect from moisture
Do not freeze Ok to freeze
Special InstructionsFollowing reconstitution, aliquot and freeze (-20°C). Stock solutions are stable for up to 6 months at -20°C.
Packaging Information
Packaged under inert gas Packaged under inert gas
Transport Information
Supplemental Information
Specifications
Global Trade Item Number
Número de referencia GTIN
5325860001 04055977241273

Documentation

AEBSF, HCl ≥99% by HPLC - CAS 30827-99-7 - Calbiochem Ficha datos de seguridad (MSDS)

Título

Ficha técnica de seguridad del material (MSDS) 

Referencias bibliográficas

Visión general referencias
Citron, M., et al. 1996. Neuron 17, 171.
Ohkubo, I., et al. 1994. J. Biochem. 116, 1182.
Mintz, G.R. 1993. BioPharm. 6, 34.
Lawson, W.B., et al. 1982. Folia Haematol. 109, 52.
Markwardt, F., et al. 1974. Biochem. Pharmacol. 23, 2247.
Markwardt, F., et al. 1973. Thromb. Res. 2, 343.
Baker, B.R., and Cory, M. 1971. 14, 119.

Folleto

Cargo
NPI Flyer- Epigenetics and Nuclear Function Feature
New Products - Antibodies, Small Molecule, Inhibitors

Licencias necesarias e Información técnica

Cargo
White Paper: Further considerations of antibody validation and usage.
Ficha técnica

Note that this data sheet is not lot-specific and is representative of the current specifications for this product. Please consult the vial label and the certificate of analysis for information on specific lots. Also note that shipping conditions may differ from storage conditions.

Revision05-December-2014 JSW
Synonyms4-(2-Aminoethyl)benzenesulfonylfluoride, HCl, 4-(2-Aminoethyl)benzene-1-sulfonyl fluoride, HCl
DescriptionSpecific irreversible inhibitor of serine proteases. Reacts covalently with a serine at the active site. Inhibits chymotrypsin, kallikrein, plasmin, thrombin, trypsin, and related thrombolytic enzymes. Stable, nontoxic alternative to PMSF (Cat. No. 52332) and DFP (Cat. No. 30967). Used at the same molar concentration (0.1-1.0 mM) as PMSF for most applications. Exhibits low inhibitory activity towards proteinase K. A material with ≥97% purity by HPLC (Cat. No. 101500) & its InSolution™ is also available (Cat. No. 508436).
FormWhite powder
Intert gas (Yes/No) Packaged under inert gas
CAS number30827-99-7
Chemical formulaC₈H₁₀FNO₂S·HCl
Purity≥99% by HPLC
SolubilityH₂O (50 mg/ml)
Storage Protect from moisture
Protect from light
+2°C to +8°C
Do Not Freeze Ok to freeze
Special InstructionsFollowing reconstitution, aliquot and freeze (-20°C). Stock solutions are stable for up to 6 months at -20°C.
Toxicity Corrosive
ReferencesCitron, M., et al. 1996. Neuron 17, 171.
Ohkubo, I., et al. 1994. J. Biochem. 116, 1182.
Mintz, G.R. 1993. BioPharm. 6, 34.
Lawson, W.B., et al. 1982. Folia Haematol. 109, 52.
Markwardt, F., et al. 1974. Biochem. Pharmacol. 23, 2247.
Markwardt, F., et al. 1973. Thromb. Res. 2, 343.
Baker, B.R., and Cory, M. 1971. 14, 119.