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104551 ACC2 Inhibitor, CD-017-0191 - Calbiochem

The ACC2 Inhibitor, CD-017-0191 controls the biological activity of ACC2. This small molecule/inhibitor is primarily used for Cell Signaling applications.

ACC2 Inhibitor, CD-017-0191 - Calbiochem: Ficha de datos de seguridad (MSDS o SDS), certificado de análisis y de calidad (CoA y CoQ), expedientes, folletos y otros documentos disponibles.

Sinónimos: 2-((2-(4-isopropoxyphenyl)-5-methyloxazol-4-yl)methylthio)oxazolo[4,5-b]pyridine

104551
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Descripción

Replacement Information

Tabla espec. clave

Empirical Formula
C₂₀H₁₉N₃O₃S

Products

Número de referenciaEmbalaje Cant./Env.
104551-10MG Frasco de vidrio 10 mg
Description
OverviewA cell-permeable and selective inhibitor of human Acetyl-CoA carboxylase 2 (ACC2) (IC50 = 2.8 µM), which does not inhibit human ACC1 at all at concentrations up to 100 µM, in vitro. It is also shown to inhibit the growth of yeast (IC50 = 3.8 µM), in which the native ACC1 gene is replaced with the human ACC2 strain; but not with the human ACC1 strain at concentrations ≤ 100 µM. This compound is not demonstrated to be toxic to human cells in culture at concentrations up to 10 µM.
Catalogue Number104551
Brand Family Calbiochem®
Synonyms2-((2-(4-isopropoxyphenyl)-5-methyloxazol-4-yl)methylthio)oxazolo[4,5-b]pyridine
References
ReferencesMarjanovic, J., et al. 2010 Proc. Natl. Acad. Sci. 107, 9093.
Product Information
FormOff-white solid
Hill FormulaC₂₀H₁₉N₃O₃S
Chemical formulaC₂₀H₁₉N₃O₃S
Structure formula ImageStructure formula Image
Quality LevelMQ100
Applications
Biological Information
Purity≥90% by HPLC
Physicochemical Information
Dimensions
Materials Information
Toxicological Information
Safety Information according to GHS
Safety Information
Product Usage Statements
Storage and Shipping Information
Ship Code Ambient Temperature Only
Toxicity Standard Handling
Storage +2°C to +8°C
Do not freeze Ok to freeze
Special InstructionsFollowing reconstitution, aliquot and freeze (-20°C). Stock solutions are stable for up to 3 months at -20°C.
Packaging Information
Transport Information
Supplemental Information
Specifications
Global Trade Item Number
Número de referencia GTIN
104551-10MG 04055977226478

Documentation

ACC2 Inhibitor, CD-017-0191 - Calbiochem Ficha datos de seguridad (MSDS)

Título

Ficha técnica de seguridad del material (MSDS) 

ACC2 Inhibitor, CD-017-0191 - Calbiochem Certificados de análisis

CargoNúmero de lote
104551

Referencias bibliográficas

Visión general referencias
Marjanovic, J., et al. 2010 Proc. Natl. Acad. Sci. 107, 9093.
Ficha técnica

Note that this data sheet is not lot-specific and is representative of the current specifications for this product. Please consult the vial label and the certificate of analysis for information on specific lots. Also note that shipping conditions may differ from storage conditions.

Revision23-February-2011 RFH
Synonyms2-((2-(4-isopropoxyphenyl)-5-methyloxazol-4-yl)methylthio)oxazolo[4,5-b]pyridine
DescriptionA cell-permeable and selective inhibitor of human Acetyl-CoA carboxylase 2 (ACC2) (IC50 = 2.8 µM), which does not inhibit human ACC1 at all at concentrations up to 100 µM, in vitro. It is also shown to inhibit the growth of yeast (IC50 = 3.8 µM), in which the native ACC1 gene is replaced with the human ACC2 strain; but not with the human ACC1 strain at concentrations ≤ 100 µM. This compound is not demonstrated to be toxic to human cells in culture at concentrations up to 10 µM.
FormOff-white solid
Chemical formulaC₂₀H₁₉N₃O₃S
Structure formulaStructure formula
Purity≥90% by HPLC
SolubilityDMSO (50 mg/ml)
Storage +2°C to +8°C
Do Not Freeze Ok to freeze
Special InstructionsFollowing reconstitution, aliquot and freeze (-20°C). Stock solutions are stable for up to 3 months at -20°C.
Toxicity Standard Handling
ReferencesMarjanovic, J., et al. 2010 Proc. Natl. Acad. Sci. 107, 9093.