Millipore Sigma Vibrant Logo
Atención: Nos hemos mudado. Los productos Merck Millipore ya no pueden adquirirse en MerckMillipore.comMás información

565750 γ-Secretase Inhibitor I - Calbiochem

The γ-Secretase Inhibitor I controls the biological activity of γ-Secretase. This small molecule/inhibitor is primarily used for Neuroscience applications.

γ-Secretase Inhibitor I - Calbiochem: Ficha de datos de seguridad (MSDS o SDS), certificado de análisis y de calidad (CoA y CoQ), expedientes, folletos y otros documentos disponibles.

Sinónimos: Z-LLNle-CHO

Primary Target: γ-secretase
565750
Purchase on Sigma-Aldrich

Descripción

Replacement Information

Tabla espec. clave

Empirical Formula
C₂₆H₄₁N₃O₅

Products

Número de referenciaEmbalaje Cant./Env.
565750-1MG Ampolla de plást. 1 mg
Description
OverviewCell permeable. Inhibits γ-secretase, a protease that cleaves the Amyloid Precursor Protein (APP) to generate β-amyloid protein. Inhibition of this enzyme is believed to aid in the prevention of Alzheimer’s disease.
Catalogue Number565750
Brand Family Calbiochem®
SynonymsZ-LLNle-CHO
References
ReferencesSkovronsky, D.M., et al. 2000. Biochemistry 39, 810.
Hartmann, T., et al. 1997. Nat. Med. 3, 1016.
Product Information
ATP CompetitiveN
FormWhite solid
Hill FormulaC₂₆H₄₁N₃O₅
Chemical formulaC₂₆H₄₁N₃O₅
Hygroscopic Hygroscopic
ReversibleN
Structure formula ImageStructure formula Image
Quality LevelMQ200
Applications
Biological Information
Primary Targetγ-secretase
Purity≥90% by HPLC
Physicochemical Information
Cell permeableY
Peptide SequenceZ-Leu-Leu-Nle-CHO (Nle = Norleucine)
Dimensions
Materials Information
Toxicological Information
Safety Information according to GHS
Safety Information
Product Usage Statements
Storage and Shipping Information
Ship Code Ambient Temperature Only
Toxicity Standard Handling
Storage -20°C
Hygroscopic Hygroscopic
Do not freeze Ok to freeze
Special InstructionsFollowing reconstitution, aliquot and freeze (-20°C). Stock solutions are stable for up to 3 months at -20°C.
Packaging Information
Packaged under inert gas Packaged under inert gas
Transport Information
Supplemental Information
Specifications
Global Trade Item Number
Número de referencia GTIN
565750-1MG 04055977267679

Documentation

γ-Secretase Inhibitor I - Calbiochem Ficha datos de seguridad (MSDS)

Título

Ficha técnica de seguridad del material (MSDS) 

γ-Secretase Inhibitor I - Calbiochem Certificados de análisis

CargoNúmero de lote
565750

Referencias bibliográficas

Visión general referencias
Skovronsky, D.M., et al. 2000. Biochemistry 39, 810.
Hartmann, T., et al. 1997. Nat. Med. 3, 1016.
Ficha técnica

Note that this data sheet is not lot-specific and is representative of the current specifications for this product. Please consult the vial label and the certificate of analysis for information on specific lots. Also note that shipping conditions may differ from storage conditions.

Revision07-January-2009 RFH
SynonymsZ-LLNle-CHO
DescriptionInhibits γ-secretase, a protease that cleaves the amyloid precursor protein (APP). Inhibition of this enzyme is believed to aid in the prevention of Alzheimer's disease.
FormWhite solid
Intert gas (Yes/No) Packaged under inert gas
Chemical formulaC₂₆H₄₁N₃O₅
Peptide SequenceZ-Leu-Leu-Nle-CHO (Nle = Norleucine)
Structure formulaStructure formula
Purity≥90% by HPLC
Solubility50% acetic acid or DMSO (10 mg/ml)
Storage -20°C
Hygroscopic
Do Not Freeze Ok to freeze
Special InstructionsFollowing reconstitution, aliquot and freeze (-20°C). Stock solutions are stable for up to 3 months at -20°C.
Toxicity Standard Handling
ReferencesSkovronsky, D.M., et al. 2000. Biochemistry 39, 810.
Hartmann, T., et al. 1997. Nat. Med. 3, 1016.