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Capture chromatography is often a bottleneck in biomanufacturing processes and a significant contributor to manufacturing cost of goods. In response to these challenges, intensification of capture chromatography using multi-column chromatography can provide increased productivity and a reduction in cost of goods. Technologies in development, such as membrane capture, aim to further these advances. Whether it is process intensification or continuous processing, these advances can meet the needs of an evolving market.
The Mobius® Multi Column Capture system is a fully automated, single-use solution to operate continuous closed capture chromatography. Coupled with an in-line dilution capability and intuitive software, the 3 columns system allows complete control of the capture step of your fed-batch or perfusion bioprocess. The system is suitable for bioreactor volumes ranging from 50 L to 2000 L.
