Merck invites you to the 1st Purification Experts Community Meeting
at the New M Lab™ Collaboration Center in Molsheim, France
This three-day event will bring together industry experts in TFF and Chromatography to share scientific knowledge, review trends and challenges, and look for innovative solutions to today’s evolving processing requirements.
The Purification Experts Community Meeting will include:
- Presentations and discussions
- Round tables
- Poster sessions
- Networking activities
We look forward to welcoming you.
Agenda*
Day 1 - Tuesday, December 11th
| 8:00 – 10:00 am | Registration |
| 10:00 – 10:30 am | Welcome |
| Frederic Sengler and Christine Bizet | |
| 10:30 – 11:15 am | Evaluating TFF capsules for SPTFF in mAb production |
| Charles Heise, Fujifilm | |
| 11:15 – 12:00 noon | Round table - TFF |
| 12:00 – 1:00 pm | Lunch |
| 1:00 – 1:45 pm | Characterization and establishment of single-pass tangential flow filtration for concentration of biomolecules |
| Nina Schlaich, Rentschler | |
| 1:45 – 2:30 pm | Round table - TFF |
| 2:30 – 3:15 pm | Break and poster session |
| 3:15 – 4:00 pm | How to reach high plasma protein concentration with single-pass TFF: A case study from Shire and Merck |
| Sylvie Defrère, Shire | |
| 4:00 – 4:45 pm | TFF: High concentration challenges |
| Iakovos Panagiotidis, BPL | |
| 5:45 – 10:00 pm | Evening event: visit of Obernai Christmas Market and dinner |
Day 2 - Wednesday, December 12th
| 9:00 – 9:15 am | Welcome day 2 |
| Frederic Sengler and Christine Bizet | |
| 9:15 – 10:00 am | Manufacturing a therapeutic fab for high concentrations – filtration and viscosity challenges |
| Christoph Feistl, Roche | |
| 10:00 – 10:45 am | Mitigation of Donnan and volume exclusion effect during UFDF |
| Florian Capito, Sanofi | |
| 10:45 – 11:15 am | Break and poster session |
| 11:15 – 12:00 noon | UF/DF optimization for a high concentration mAb formulation |
| Thibault Lasgouzes, UCB Pharma | |
| 12:00 – 1:00 pm | Lunch |
| 1:00 – 1:45 pm | Intensified DSP tools review |
| Victor Pasquier, Merck Healthcare | |
| 1:45 – 2:30 pm | Development of Next Generation mAb purification with focus on flow through cation exchanger |
| Cui Tingting, Medimmune | |
| 2:30 – 3:15 pm | Break and poster session |
| 3:15 – 4:00 pm | Round table - Chromatography |
| 6:00 – 10:30 pm | Christmas market and evening event at "Les Harras" in Strasbourg |
Day 3 - Thursday, December 13th
| 9:00 – 9:45 am | Generic approach for chromatography column packing and testing |
| Arvid Rehm, Rentschler | |
| 9:45 – 10:30 am | Development of a high throughput chromatography screening platform for vaccine purification |
| Bruno André, GSK | |
| 10:30 – 11:15 am | Break and poster session |
| 11:15 – 12:00 noon | Round table - Chromatography |
| 12:00 – 12:45 pm | Removal of high molecular weight species by Protein A chromatography |
| Maria Marza Perez, Synthon | |
| 12:45 – 1:45 pm | Lunch |
| 1:45 – 2:30 pm | Approaches in HCP removal in monoclonal antibody purification |
| Thomas Lagautrière, Merck Biodevelopment | |
| 2:30 – 3:15 pm | Cation exchanger step improvements for efficient virus filtration in hyperimmune IgG manufacture |
| Anna Hull, BPL | |
| 3:15 – 3:30 pm | Closing session |
* Agenda subject to change. Attendance to the Purification Experts Community Meeting is limited and available to pharma or biopharma manufacturers and academics only. The offer does not extend to any company that provides pharma or biopharma products or services. We reserve the right to revoke or refuse participation at any time. Attendance is free, though registration is required. Lunch, coffee break and dinner are provided courtesy of Merck KGaA, Darmstadt, Germany. Travel costs and hotel accommodation are at the expense of the attendees. A block of rooms has been booked at different hotels close to the meeting venue.
Round table TFF
1. Closed processing and purification
Mr Mongi, Sanofi, and Karine Peron, Merck
2. Industry trends and adoption of single-use and closed TFF processing
Nick Landry and Paul Beckett, Merck
Round table Chromatography
1. Large scale manufacturing challenges including packing, storage, cleaning
Nicolas Laroudie, Merck
2. Enable Next Generation Bioprocessing
Mochao Zhao, Merck
Venue: M Lab™ Collaboration Center
Merck KGaA, Darmstadt, Germany
39 Route Industrielle de la Hardt
67120 Molsheim, France