Millipore Sigma Vibrant Logo
Attention: We have moved. Merck Millipore products are no longer available for purchase on MerckMillipore.com.Learn More

GF317 TGF-β-III Protein, Human Recombinant Animal Free

TGF-β-III is one of three closely related mammalian members of the large TGF-β superfamily.Recombinant animal free human TGF-β-III is manufactured using all non-animal reagents.

MSDS (material safety data sheet) or SDS, CoA and CoQ, dossiers, brochures and other available documents.
UniProt Number: P10600 Entrez Gene Number: 7043
GF317
10µg  
Purchase on Sigma-Aldrich

Overview

Replacement Information

Key Spec Table

SourcePurity
E. coli.Product is endotoxin free (<0.1 ng/μg of protein (<1 EU/μg) and greater than 98% pure by SDS-PAGE gel and HPLC analyses.
Description
Catalogue NumberGF317
DescriptionTGF-β-III Protein, Human Recombinant Animal Free
Alternate Names
  • Transforming Growth Factor Beta 3
  • TGF-Beta-3
  • TGF-Beta-III
Background InformationTGF-β-III (transforming growth factor beta III) is one of three closely related mammalian members of the large TGF-β superfamily. TGF-β-I, TGF-β-II and TGF-β-III are highly pleiotropic cytokines that are proposed to act as cellular switches that regulate processes such as immune function, proliferation and epithelial mesenchymal transition. TGF-β3 regulates molecules involved in cellular adhesion and extracellular matrix formation during the process of palate development. TGF-β3 also plays an essential role in controlling the development of lungs in mammals and controls wound healing by regulating the movements of epidermal and dermal cells in injured skin. Recombinant TGF-β-III is a 25.0 kDa protein composed of two identical 112 amino acid polypeptide chains linked by a single disulfide bond.
References
Product Information
Formulation
PresentationProduct is filtered through a 0.2 micron filter before lyophilization.
Quality LevelMQ100
Applications
ApplicationTGF-β-III is one of three closely related mammalian members of the large TGF-β superfamily.Recombinant animal free human TGF-β-III is manufactured using all non-animal reagents.
Biological Information
PurityProduct is endotoxin free (<0.1 ng/μg of protein (<1 EU/μg) and greater than 98% pure by SDS-PAGE gel and HPLC analyses.
SourceE. coli.
Entrez Gene Number
UniProt Number
Physicochemical Information
Dimensions
Materials Information
Toxicological Information
Safety Information according to GHS
Safety Information
Product Usage Statements
Quality AssuranceDetermined by TGF-β-III’s ability to inhibit the mouse IL-4-dependent proliferation of mouse HT-2 cells. The expected ED50 is ≤ 0.05 ng/ml, corresponding to a specific activity of ≥ 2 x 107 units/mg.
Usage Statement
  • Unless otherwise stated in our catalog or other company documentation accompanying the product(s), our products are intended for research use only and are not to be used for any other purpose, which includes but is not limited to, unauthorized commercial uses, in vitro diagnostic uses, ex vivo or in vivo therapeutic uses or any type of consumption or application to humans or animals.
Storage and Shipping Information
Storage ConditionsStore at -20°C for up to 6 months from date of receipt.
Packaging Information
Material Size10µg
Transport Information
Supplemental Information
Specifications
Global Trade Item Number
Catalogue Number GTIN
GF317 04053252599682

Documentation

TGF-β-III Protein, Human Recombinant Animal Free SDS

Title

Safety Data Sheet (SDS) 

TGF-β-III Protein, Human Recombinant Animal Free Certificates of Analysis

TitleLot Number
Recombinant Animal Free -2810616 2810616
Recombinant Animal Free Human TGF-#946;-III - Q2048993 Q2048993
Recombinant Animal Free Human TGF-β-III - 3381327 3381327
Recombinant Animal Free Human TGF-β-III - 3547783 3547783
Recombinant Animal Free Human TGF-β-III - 3752702 3752702
Recombinant Animal Free Human TGF-β-III - 4045878 4045878
Recombinant Animal Free Human TGF-β-III - 4177424 4177424
Recombinant Animal Free Human TGF-β-III -2673191 2673191

Related Products & Applications

Product Families

Cytokines and Growth Factors

EMD Millipore offers a comprehensive range of highly purified bioactive cytokines and growth factors for use in human, mouse, and rat cell culture, stem cell differentiation and ELISA studies.
Learn More >>

Categories

Life Science Research > Proteins and Enzymes > Cytokines & Growth Factors
Life Science Research > Cell Culture and Systems > Cell Culture Media and Supplements > Cell Culture Supplements > Cytokines & Growth Factors