Millipore Sigma Vibrant Logo
Attention: We have moved. Merck Millipore products are no longer available for purchase on MerckMillipore.com.Learn More

FCABS352A4 Milli-Mark™ Anti-Nanog-Alexa Fluor 488 Antibody, NT

Milli-Mark Anti-Nanog-Alexa Fluor 488 Antibody, N-terminus is an antibody against Nanog-Alexa Fluor 488 for use in FC.

MSDS (material safety data sheet) or SDS, CoA and CoQ, dossiers, brochures and other available documents.
Research Category: Stem Cell Research Research Sub-Category: Pluripotent & Early Differentiation Gene Symbol: FLJ12581, FLJ40451, hNanog UniProt Number: Q9H9S0
FCABS352A4
100 tests  
Purchase on Sigma-Aldrich

Special Offers

Overview

Replacement Information

Special Offers

100% Performance Guaranteed

Key Spec Table

Species ReactivityKey ApplicationsHostFormatAntibody Type
H, M, RFCRbAlexaFluor®488Polyclonal Antibody
Description
Catalogue NumberFCABS352A4
Trade Name
  • Milli-Mark
DescriptionMilli-Mark™ Anti-Nanog-Alexa Fluor 488 Antibody, NT
Alternate Names
  • Homeobox transcription factor Nanog
  • Nanog homeobox
Background InformationNANOG is a gene expressed in embryonic stem cells (ESCs) and is thought to be a key factor in maintaining pluripotency. NANOG thought to function in concert with other factors such as POU5F1 and SOX2 to establish ESC identity. These cells offer an important area of study because of their ability to maintain pluripotency, i.e., these cells have the ability to become virtually any cell of any of the three germ layers (endoderm, ectoderm, mesoderm).
NANOG may be useful in the immunohistochemical diagnosis of tumors. NANOG is expressed in germ cells of the fetus and in some germ cell tumors of the gonads and central nervous system (CNS).
References
Product Information
FormatAlexaFluor®488
Control
  • 2102 Ep cells
PresentationPurified rabbit polyclonal IgG conjugated to Alexa Fluor® 488 in PBS with 0.1% sodium azide and 15 mg/mL BSA
Quality LevelMQ100
Applications
ApplicationMilli-Mark Anti-Nanog-Alexa Fluor 488 Antibody, N-terminus is an antibody against Nanog-Alexa Fluor 488 for use in FC.
Key Applications
  • Flow Cytometry
Biological Information
ImmunogenLinear peptide from mouse Nanog.
EpitopeN-terminus
HostRabbit
SpecificityAntibody recognizes NANOG.
IsotypeIgG
Species Reactivity
  • Human
  • Mouse
  • Rat
Species Reactivity NoteTested and passed on Human. Predicted to react with Mouse, Rat based on 100% sequence homology.
Antibody TypePolyclonal Antibody
Entrez Gene Number
Gene Symbol
  • FLJ12581
  • FLJ40451
  • hNanog
Purification MethodAntigen Affinity Purified
UniProt Number
UniProt SummaryTranscription regulator involved in inner cell mass and embryonic stem (ES) cells proliferation and self-renewal. Imposes pluripotency on ES cells and prevents their differentiation towards extraembryonic endoderm and trophectoderm lineages. Blocks bone morphogenetic protein-induced mesoderm differentiation of ES cells by physically interacting with SMAD1 and interfering with the recruitment of coactivators to the active SMAD transcriptional complexes. Acts as a transcriptional activator or repressor, when overexpressed, promotes cells to enter into S phase and proliferation.
Molecular Weight 34 kDa Calculated
Physicochemical Information
Dimensions
Materials Information
Toxicological Information
Safety Information according to GHS
Safety Information
Product Usage Statements
Quality AssuranceEvaluated by flow cytometry using 2102 Ep cells
Usage Statement
  • Unless otherwise stated in our catalog or other company documentation accompanying the product(s), our products are intended for research use only and are not to be used for any other purpose, which includes but is not limited to, unauthorized commercial uses, in vitro diagnostic uses, ex vivo or in vivo therapeutic uses or any type of consumption or application to humans or animals.
Storage and Shipping Information
Storage ConditionsMaintain refrigerated at 2-8 °C protected from light in undiluted aliquots for up to 6 months from date of receipt.
Packaging Information
Material Size100 tests
Transport Information
Supplemental Information
Specifications
Global Trade Item Number
Catalogue Number GTIN
FCABS352A4 04053252750298

Documentation

Milli-Mark™ Anti-Nanog-Alexa Fluor 488 Antibody, NT SDS

Title

Safety Data Sheet (SDS) 

Milli-Mark™ Anti-Nanog-Alexa Fluor 488 Antibody, NT Certificates of Analysis

TitleLot Number
Milli-Mark Anti-Nanog-Alexa Fluor#174; 488, N-terminus - 2142679 2142679
Milli-Mark Anti-Nanog-Alexa Fluor#174; 488, N-terminus - 1959253 1959253
Milli-Mark Anti-Nanog-Alexa Fluor#174; 488, N-terminus - 1973231 1973231
Milli-Mark Anti-Nanog-Alexa Fluor#174; 488, N-terminus - 2042799 2042799
Milli-Mark Anti-Nanog-Alexa Fluor#174; 488, N-terminus - 2110558 2110558
Milli-Mark Anti-Nanog-Alexa Fluor#174; 488, N-terminus - 2270275 2270275
Milli-Mark Anti-Nanog-Alexa Fluor#174; 488, N-terminus - 2271190 2271190
Milli-Mark Anti-Nanog-Alexa Fluor#174; 488, N-terminus - NG1906885 NG1906885
Milli-Mark Anti-Nanog-Alexa Fluor#174; 488, N-terminus - NRG1868516 NRG1868516
Milli-Mark™ Anti-Nanog-Alexa Fluor 488, N-terminus -2679489 2679489
Show more

Related Products & Applications

Related Products

Catalogue Number Description
17-655 ChIPAb+ Nanog Antibody - ChIP Validated Antibody and Primer Set
AB5731 Anti-Nanog Antibody, NT
MABD24 Anti-NANOG Antibody, clone 7F7.1
MABD24A4 Anti-NANOG Antibody, clone 7F7.1, Alexa Fluor® 488 conjugate

Product Families

Flow Cytometry Kits & Antibodies

Merck's Milli-Mark and FlowCellect brands include fluorescent conjugated antibodies and multiparameter kits for cellular analysis. Designed, optimized, and validated for flow.
Learn More >>

Related Products By: Brand Facete

Milli-Mark™

Categories

Life Science Research > Antibodies and Assays > Primary Antibodies