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437720 Lipoxin A₄ - CAS 89663-86-5 - Calbiochem

437720
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Overview

Key Spec Table

CAS #Empirical Formula
89663-86-5C₂₀H₃₂O₅

Products

Catalogue NumberPackaging Qty/Pack
437720-25UG Glass bottle 25 μg
Description
OverviewPotent inhibitor of cytotoxic activity of human natural killer cells; shown to be as potent as LTB4 in stimulating human neutrophils to generate superoxides. Involved in contractile responses and acts as a potent activator of human protein kinase C. Stimulates rapid lipid remodeling and pertussis-sensitive release of arachidonic acid in polymorphonuclear leukocytes. Stimulates MAP kinases via activation of G protein-coupled receptors.
Caution! Product contains volatile liquid. Keep product cold at all times.
Catalogue Number437720
Brand Family Calbiochem®
SynonymsLXA₄, 5(S),6(R),15(S)-Trihydroxyeicosa-7-trans-9-trans-11-cis-13-trans-tetraenoic Acid
References
ReferencesMcMahon, B., et al. 2000. J. Biol. Chem. 275, 27566.
Soyombo, O., et al. 1994. Allergy 49, 230.
Flore, S., et al. 1992. J. Biol. Chem. 267, 16168.
Badr, K.F., et al. 1989. Proc. Natl. Acad. Sci. USA 86, 3438.
Product Information
CAS number89663-86-5
ATP CompetitiveN
FormLiquid
FormulationIn Ethanol.
Hill FormulaC₂₀H₃₂O₅
Chemical formulaC₂₀H₃₂O₅
ReversibleN
Structure formula ImageStructure formula Image
Quality LevelMQ100
Biological Information
Primary TargetPotent inhibitor of cytotoxic activity of human natural killer cells
Purity≥95% by HPLC
Physicochemical Information
Cell permeableN
Safety Information
R PhraseR: 11-36/37/38

Highly flammable.
Irritating to eyes, respiratory system and skin.
S PhraseS: 16-26-36-7

Keep away from sources of ignition - No Smoking.
In case of contact with eyes, rinse immediately with plenty of water and seek medical advice.
Wear suitable protective clothing.
Keep container tightly closed.
Storage and Shipping Information
Ship Code Dry Ice Only
Toxicity Flammable
Hazardous Materials Attention: Due to the nature of the Hazardous Materials in this shipment, additional shipping charges may be applied to your order. Certain sizes may be exempt from the additional hazardous materials shipping charges. Please contact your local sales office for more information regarding these charges.
Storage ≤ -70°C
Do not freeze Ok to freeze
Special InstructionsFollowing initial thaw, aliquot and freeze (-70°C).
Global Trade Item Number
Catalogue Number GTIN
437720-25UG 04055977186888