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401478 IκB Kinase Inactive Control Peptide, Cell-Permeable - Calbiochem

An inactive control for IκB Kinase Inhibitor Peptide.

MSDS (material safety data sheet) or SDS, CoA and CoQ, dossiers, brochures and other available documents.

Synonyms: Ac-AAVALLPAVLLALLAPDDRHDAGLDAMKDE-NH₂

Primary Target: An inactive control for IκB Kinase Inhibitor Peptide
401478
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Overview

Key Spec Table

Empirical Formula
C₁₃₈H₂₂₉N₃₇O₄₃S

Products

Catalogue NumberPackaging Qty/Pack
401478-1MG Plastic ampoule 1 mg
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Description
OverviewAn inactive control for IκB Kinase Inhibitor Peptide (Cat. No. 401477). A 14-amino acid peptide corresponding to the mutated recognition sequence of IκB (Ser32→Ala and Ser36→Ala) fused to the hydrophobic region of the fibroblast growth factor signal peptide to aid in cellular delivery. Does not have any inhibitory effect on LPS-induced IκB degradation by IκB kinases (IKK) in RAW 264.7 cells at 50 µg/ml.
Catalogue Number401478
Brand Family Calbiochem®
SynonymsAc-AAVALLPAVLLALLAPDDRHDAGLDAMKDE-NH₂
References
ReferencesSwaroop, N., et al. 2001. Pharm. Res. 18, 1631.
Traenckner, E.B., et al. 1995. EMBO J. 14, 2876.
Product Information
ATP CompetitiveN
FormOff-white to white solid
FormulationSupplied as a trifluoroacetate salt.
Hill FormulaC₁₃₈H₂₂₉N₃₇O₄₃S
Chemical formulaC₁₃₈H₂₂₉N₃₇O₄₃S
Hygroscopic Hygroscopic
ReversibleN
Quality LevelMQ100
Biological Information
Primary TargetAn inactive control for IκB Kinase Inhibitor Peptide
Purity≥97% by HPLC
Physicochemical Information
Cell permeableN
Peptide SequenceAc-Ala-Ala-Val-Ala-Leu-Leu-Pro-Ala-Val-Leu-Leu-Ala-Leu-Leu-Ala-Pro-Asp-Asp-Arg-His-Asp-Ala-Gly-Leu-Asp-Ala-Met-Lys-Asp-Glu-NH₂
Storage and Shipping Information
Ship Code Blue Ice Only
Toxicity Standard Handling
Storage -20°C
Protect from Light Protect from light
Hygroscopic Hygroscopic
Do not freeze Ok to freeze
Special InstructionsFollowing reconstitution aliquot and freeze (-20°C). Stock solutions are stable for up to 3 months at -20°C.
Packaging Information
Packaged under inert gas Packaged under inert gas
Global Trade Item Number
Catalogue Number GTIN
401478-1MG 04055977211931