Millipore Sigma Vibrant Logo
Attention: We have moved. Merck Millipore products are no longer available for purchase on MerckMillipore.com.Learn More

437694 DL-α-Lipoic Acid, Dihydro- - CAS 462-20-4 - Calbiochem

An effective antioxidant.

MSDS (material safety data sheet) or SDS, CoA and CoQ, dossiers, brochures and other available documents.

Synonyms: DHLA, Dihydrolipoic Acid, Thiocytic Acid, Dihydro-

437694
Purchase on Sigma-Aldrich

Overview

Replacement Information

Key Spec Table

CAS #Empirical Formula
462-20-4C₈H₁₆O₂S₂

Products

Catalogue NumberPackaging Qty/Pack
437694-50MG Plastic ampoule 50 mg
Description
OverviewAn effective antioxidant. Scavenges hypochlorous acid, peroxyl, superoxide, hydroxyl, and nitric oxide radicals. Also exhibits prooxidant properties, as demonstrated by its ability to reduce iron ions and to generate reactive sulfur-containing radicals that can damage certain proteins, such as α1-antiproteinase and creatine kinase. DHLA has recently been shown to inhibit apoptosis in rat thymocytes induced by methylprednisolone and etoposide.
Catalogue Number437694
Brand Family Calbiochem®
SynonymsDHLA, Dihydrolipoic Acid, Thiocytic Acid, Dihydro-
References
ReferencesPacker, L., et al. 1997. Adv. Pharmacol. 38, 79.
Bustamante, J., et al. 1995. Free Radic. Biol. Med. 19, 339.
Scott, B.C., et al. 1994. Free Radic. Res. 20, 119.
Product Information
CAS number462-20-4
ATP CompetitiveN
FormLight yellow liquid
Hill FormulaC₈H₁₆O₂S₂
Chemical formulaC₈H₁₆O₂S₂
ReversibleN
Structure formula ImageStructure formula Image
Quality LevelMQ100
Applications
Biological Information
Primary TargetScavenges hypochlorous acid, peroxyl, superoxide, hydroxyl, and nitric oxide radicals
Purity≥95% by TLC
Physicochemical Information
Cell permeableN
Dimensions
Materials Information
Toxicological Information
Safety Information according to GHS
Safety Information
R PhraseR: 36/37/38

Irritating to eyes, respiratory system and skin.
S PhraseS: 26-36

In case of contact with eyes, rinse immediately with plenty of water and seek medical advice.
Wear suitable protective clothing.
Product Usage Statements
Storage and Shipping Information
Ship Code Ambient Temperature Only
Toxicity Irritant
Storage +2°C to +8°C
Protect from Light Protect from light
Do not freeze Ok to freeze
Packaging Information
Packaged under inert gas Packaged under inert gas
Transport Information
Supplemental Information
Specifications
Global Trade Item Number
Catalogue Number GTIN
437694-50MG 04055977186857

Documentation

DL-α-Lipoic Acid, Dihydro- - CAS 462-20-4 - Calbiochem SDS

Title

Safety Data Sheet (SDS) 

DL-α-Lipoic Acid, Dihydro- - CAS 462-20-4 - Calbiochem Certificates of Analysis

TitleLot Number
437694

References

Reference overview
Packer, L., et al. 1997. Adv. Pharmacol. 38, 79.
Bustamante, J., et al. 1995. Free Radic. Biol. Med. 19, 339.
Scott, B.C., et al. 1994. Free Radic. Res. 20, 119.
Data Sheet

Note that this data sheet is not lot-specific and is representative of the current specifications for this product. Please consult the vial label and the certificate of analysis for information on specific lots. Also note that shipping conditions may differ from storage conditions.

Revision27-October-2009 RFH
SynonymsDHLA, Dihydrolipoic Acid, Thiocytic Acid, Dihydro-
DescriptionAn effective antioxidant. Scavenges hypochlorous acid, peroxyl, superoxide, hydroxyl and nitric oxide radicals. Also exhibits prooxidant properties, as demonstrated by its ability to reduce iron ions and to generate reactive sulfur-containing radicals that can damage certain proteins, such as α1-antiproteinase and creatine kinase. DHLA has recently been shown to inhibit apoptosis in rat thymocytes induced by methylprednisolone and etoposide.
FormLight yellow liquid
Intert gas (Yes/No) Packaged under inert gas
CAS number462-20-4
Chemical formulaC₈H₁₆O₂S₂
Structure formulaStructure formula
Purity≥95% by TLC
SolubilityEthanol (50 mg/ml)
Storage Protect from light
+2°C to +8°C
Do Not Freeze Ok to freeze
Toxicity Irritant
ReferencesPacker, L., et al. 1997. Adv. Pharmacol. 38, 79.
Bustamante, J., et al. 1995. Free Radic. Biol. Med. 19, 339.
Scott, B.C., et al. 1994. Free Radic. Res. 20, 119.