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12-330 Casein Kinase 2 Substrate Peptide

12-330
1 µmol  
Purchase on Sigma-Aldrich

Overview

Replacement Information
Description
Catalogue Number12-330
Brand Family Upstate
Trade Name
  • Upstate
DescriptionCasein Kinase 2 Substrate Peptide
References
Product Information
Presentation20 mM MOPS, pH 7.2; 25 mM b-glycerol phosphate; 5 mM EGTA; 1 mM sodium orthovanadate; 1 mM dithiothreitol
Quality LevelMQ300
Applications
ApplicationCasein Kinase 2 Substrate Peptide primarily used in Kinase Assays.
Key Applications
  • Kinase Assay
Biological Information
Entrez Gene Number
Entrez Gene SummaryThis gene encodes the beta subunit of casein kinase II, a ubiquitous protein kinase which regulates metabolic pathways, signal transduction, transcription, translation, and replication. The enzyme is composed of three subunits, alpha, alpha prime and beta, which form a tetrameric holoenzyme. The alpha and alpha prime subunits are catalytic, while the beta subunit serves regulatory functions. The enzyme localizes to the endoplasmic reticulum and the Golgi apparatus.
Gene Symbol
  • CSNK2B
  • Phosvitin
  • CK2B
  • CSK2B
  • MGC138224
  • MGC138222
  • CK2N
  • G5a
  • phosvitin
  • G5A
Protein TargetCK2
Target Sub-FamilyCMGC
UniProt Number
UniProt SummaryFUNCTION: SwissProt: P67870 # Participates in Wnt signaling (By similarity). Plays a complex role in regulating the basal catalytic activity of the alpha subunit.
SIZE: 215 amino acids; 24942 Da
SUBUNIT: Tetramer composed of an alpha subunit, an alpha' subunit and two beta subunits. Interacts with CD163. Also component of a CK2-SPT16-SSRP1 complex composed of SSRP1, SUPT16H, CSNK2A1, CSNK2A2 and CSNK2B, the complex associating following UV irradiation.
PTM: Phosphorylated by alpha subunit.
SIMILARITY: SwissProt: P67870 ## Belongs to the casein kinase 2 subunit beta family.
Physicochemical Information
Dimensions
Materials Information
Toxicological Information
Safety Information according to GHS
Safety Information
Product Usage Statements
Quality AssuranceRoutinely evaluated as a substrate in a kinase assay.
Usage Statement
  • Unless otherwise stated in our catalog or other company documentation accompanying the product(s), our products are intended for research use only and are not to be used for any other purpose, which includes but is not limited to, unauthorized commercial uses, in vitro diagnostic uses, ex vivo or in vivo therapeutic uses or any type of consumption or application to humans or animals.
Storage and Shipping Information
Storage ConditionsStable for 2 years at -20°C from date of shipment. Aliquot to avoid repeated freezing and thawing. For maximum recovery of the product, centrifuge the original vial prior to removing the cap.
Packaging Information
Material Size1 µmol
Transport Information
Supplemental Information
Specifications
Global Trade Item Number
Catalogue Number GTIN
12-330 04053252512360

Documentation

Casein Kinase 2 Substrate Peptide SDS

Title

Safety Data Sheet (SDS) 

Casein Kinase 2 Substrate Peptide Certificates of Analysis

TitleLot Number
Casein Kinase 2 Substrate Peptide - 0607034940 0607034940
Casein Kinase 2 Substrate Peptide - 15379 15379
Casein Kinase 2 Substrate Peptide - 16591 16591
Casein Kinase 2 Substrate Peptide - 17562 17562
Casein Kinase 2 Substrate Peptide - 18103 18103
Casein Kinase 2 Substrate Peptide - 18643 18643
Casein Kinase 2 Substrate Peptide - 19696 19696
Casein Kinase 2 Substrate Peptide - 2006547 2006547
Casein Kinase 2 Substrate Peptide - 2032308 2032308
Casein Kinase 2 Substrate Peptide - 20668 20668

Related Products & Applications

Product Families

Categories

Life Science Research > Proteins and Enzymes > Substrate & Control Proteins > Kinase & Phosphatase Substrates
Life Science Research > Drug Discovery and Development > Kinase & Phosphatase Screening > Kinase & Phosphatase Substrates