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102584 Caffeine

EMPROVE® ESSENTIAL Ph Eur,BP,USP

Caffeine MSDS (material safety data sheet) or SDS, CoA and CoQ, dossiers, brochures and other available documents.

Synonyms: 7-Methyltheobromine, 1,3,7-Trimethylxanthine, 3,7-Dihydro-1,3,7-trimethyl-1H-purine-2,6-dione

CAS #: 58-08-2 EC Number: 200-362-1 Molar Mass: 194.19 g/mol Hill Formula: C₈H₁₀N₄O₂ Grade: Ph Eur,BP,USP
102584
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Overview

Replacement Information

Key Spec Table

CAS #EC NumberHill FormulaMolar MassGrade Value
58-08-2200-362-1C₈H₁₀N₄O₂194.19 g/molPh Eur,BP,USP

Products

Catalogue NumberPackaging Qty/Pack
1025841000 Plastic bottle 1 kg
1025849050 Fibre carton 50 kg
Description
Catalogue Number102584
Synonyms7-Methyltheobromine, 1,3,7-Trimethylxanthine, 3,7-Dihydro-1,3,7-trimethyl-1H-purine-2,6-dione
References
Product Information
CAS number58-08-2
EC index number613-086-00-5
EC number200-362-1
GradePh Eur,BP,USP
Hill FormulaC₈H₁₀N₄O₂
Molar Mass194.19 g/mol
HS Code2939 30 10
Structure formula ImageStructure formula Image
Quality LevelMQ500
Applications
Biological Information
Physicochemical Information
Density1.23 g/cm3 (18 °C)
Ignition temperature>600 °C
Melting Point235 - 239 °C
pH value5.5 - 6.5 (10 g/l, H₂O, 20 °C)
Vapor pressure20 hPa (80 °C)
Bulk density220 kg/m3
Solubility20 g/l
Dimensions
Materials Information
Toxicological Information
LD 50 oralLD50 Rat 367.7 mg/kg
Safety Information according to GHS
Hazard Pictogram(s) Hazard Pictogram(s)
Hazard Statement(s)H302: Harmful if swallowed.
Precautionary Statement(s)P264: Wash skin thoroughly after handling.
P270: Do not eat, drink or smoke when using this product.
P301 + P312: IF SWALLOWED: Call a POISON CENTER/doctor if you feel unwell.
P501: Dispose of contents/ container to an approved waste disposal plant.
Signal WordWarning
Storage class10 - 13 Other liquids and solids
WGKWGK 1 slightly hazardous to water
Disposal3
Relatively unreactive organic reagents should be collected in container A. If halogenated, they should be collected in container B. For solid residues use container C.
Safety Information
Categories of dangerharmful
Product Usage Statements
Storage and Shipping Information
StorageStore at +2°C to +30°C.
Packaging Information
Transport Information
Declaration (railroad and road) ADR, RIDKein Gefahrgut
Declaration (transport by air) IATA-DGRNo Dangerous Good
Declaration (transport by sea) IMDG-CodeNo Dangerous Good
Supplemental Information
Specifications
Assay (perchloric acid titration, calculated on dried substance)98.5 - 101.5 %
Assay (HPLC, calc. on anhydrous substance)98.5 - 101.0 %
Identity (IR)passes test
Identity (HPLC)passes test
Identity (wet chemistry)passes test
Identity (Melting point)234 - 239 °C
Appearance of solution (1 %; water)passes test
Aciditypasses test
Sulfate (SO₄)≤ 500 ppm
Chloroform (HS-GC)≤ 60 ppm
Related substances (HPLC, EP) (Highest single impurity)≤ 0.10 %
Related substances (HPLC, EP) (Sum of all impurities)≤ 0.10 %
Chromatographic purity (USP) (Highest single impurity)≤ 0.1 %
Chromatographic purity (USP) (Sum of all impurities)≤ 0.1 %
Theophylline (HPLC)≤ 0.10 %
Other residual solvents (ICH Q3C)excluded by the manufacturing process
Sulfated ash≤ 0.1 %
Loss on Drying (105 °C)≤ 0.5 %
Elemental impurity specifications have been set considering ICH Q3D (Guideline for Elemental Impurities). Class 1-3 elements are not likely to be present above the ICH Q3D option 1 limit, unless specified and indicated (*).
Corresponds to Ph Eur, BP, USP
Global Trade Item Number
Catalogue Number GTIN
1025841000 04022536034980
1025849050 04022536035000

Documentation

Material Qualification Dossier

TitleVersion
6.0

Operational Excellence Dossier

Title

Caffeine SDS

Title

Safety Data Sheet (SDS) 

Caffeine Certificates of Analysis

Product Number PackagingSpecificationLot Number
1025841000 Plastic bottlePDF Specification Document
1025849050 Fibre cartonPDF Specification Document

Certificates

Title