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MABT368 Anti-Troponin T (Cardiac Muscle) Antibody, clone 9C2.1

Detect Troponin T using this Anti-Troponin T (Cardiac Muscle) Antibody, clone 9C2.1 validated for use in Western Blotting, Immunohistochemistry.

MSDS (material safety data sheet) or SDS, CoA and CoQ, dossiers, brochures and other available documents.
Research Category: Cell Structure Research Sub-Category: Cytoskeleton Gene Symbol: TNNT2, CMD1D, CMH2, RCM3 UniProt Number: P45379
MABT368
100 μg  
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Key Spec Table

Species ReactivityKey ApplicationsHostFormatAntibody Type
M, RWB, IHCMPurifiedMonoclonal Antibody
Description
Catalogue NumberMABT368
DescriptionAnti-Troponin T (Cardiac Muscle) Antibody, clone 9C2.1
Alternate Names
  • Troponin T, cardiac muscle
  • Cardiac muscle troponin T
  • cTnT
  • TnTc
Background InformationTroponin T, cardiac muscle (UniProt P45379; also known as Cardiac muscle troponin T, cTnT, TnTc) is encoded by the TNNT2 (also known as CMD1D, CMH2, RCM3) gene (Gene ID 7139) in human. Troponin is a complex composed of three regulatory proteins, troponin C, troponin I, and troponin T). Troponin is found in both skeletal muscle and cardiac muscle where it plays an integral role in muscle contraction. Troponin T (TnT) is the component that binds tropomyosin, while troponin I (TnI) binds actin in thin myofilaments to hold the actin-tropomyosin complex in place. Three tissue TnT types exist, the slow skeletal troponin T1 encoded by the TNNT1 gene, the cardiac troponin T2 encoded by the TNNT2 gene, and the fast skeletal troponin T3 encoded by the TNNT3 gene.
References
Product Information
FormatPurified
PresentationPurified mouse monoclonal IgG2bκ antibody in buffer containing 0.1 M Tris-Glycine (pH 7.4), 150 mM NaCl with 0.05% sodium azide.
Quality LevelMQ100
Applications
ApplicationDetect Troponin T using this Anti-Troponin T (Cardiac Muscle) Antibody, clone 9C2.1 validated for use in Western Blotting, Immunohistochemistry.
Key Applications
  • Western Blotting
  • Immunohistochemistry
Application NotesImmunohistochemistry Analysis: A 1:50 dilution from a representative lot detected Troponin T (Cardiac Muscle) in rat cardiac muscle tissue.
Biological Information
ImmunogenRecombinant human cardiac muscle troponin T internal fragment.
EpitopeInternal.
Clone9C2.1
ConcentrationPlease refer to lot specific datasheet.
HostMouse
SpecificityExpected to react with human troponin T spliced isoforms 1-8 and 10, as well as all four of mouse troponin T spliced isoforms (Embryonic, A1, A2, and A3B isoforms; UniProt P50752) and both of rat troponin T spliced isoforms (Embryonic and Adult isoforms; UniProt P50753)
IsotypeIgG2bκ
Species Reactivity
  • Mouse
  • Rat
Species Reactivity NoteMouse, Rat. Predicted to react with Human based on 100% sequence homology.
Antibody TypeMonoclonal Antibody
Entrez Gene Number
Gene Symbol
  • TNNT2
  • CMD1D
  • CMH2
  • RCM3
Purification MethodProtein G Purified
UniProt Number
Molecular Weight~36 kDa observed. 35.8 kDa (isoform Embryonic), 35.0 kDa (isoform A1), 34.5 kDa (isoform A2), and 34.2 kDa (Isoform A3B) of mouse cardiac muscle troponin T spliced isoforms calculated.
Physicochemical Information
Dimensions
Materials Information
Toxicological Information
Safety Information according to GHS
Safety Information
Product Usage Statements
Quality AssuranceEvaluated by Western Blotting in mouse heart tissue lysate.

Western Blotting Analysis: 1.0 µg/mL of this antibody detected Troponin T (Cardiac Muscle) in 10 µg of mouse heart tissue lysate.
Usage Statement
  • Unless otherwise stated in our catalog or other company documentation accompanying the product(s), our products are intended for research use only and are not to be used for any other purpose, which includes but is not limited to, unauthorized commercial uses, in vitro diagnostic uses, ex vivo or in vivo therapeutic uses or any type of consumption or application to humans or animals.
Storage and Shipping Information
Storage ConditionsStable for 1 year at 2-8°C from date of receipt.
Packaging Information
Material Size100 μg
Transport Information
Supplemental Information
Specifications
Global Trade Item Number
Catalogue Number GTIN
MABT368 04055977312966

Documentation

Anti-Troponin T (Cardiac Muscle) Antibody, clone 9C2.1 SDS

Title

Safety Data Sheet (SDS) 

Anti-Troponin T (Cardiac Muscle) Antibody, clone 9C2.1 Certificates of Analysis

TitleLot Number
Anti-Troponin T (Cardiac Muscle), clone 9C2.1 3164907
Anti-Troponin T (Cardiac Muscle), clone 9C2.1 - 3230498 3230498
Anti-Troponin T (Cardiac Muscle), clone 9C2.1 - 3419580 3419580
Anti-Troponin T (Cardiac Muscle), clone 9C2.1 - 3537581 3537581
Anti-Troponin T (Cardiac Muscle), clone 9C2.1 - 3776089 3776089
Anti-Troponin T (Cardiac Muscle), clone 9C2.1 - 4139147 4139147
Anti-Troponin T (Cardiac Muscle), clone 9C2.1 - 4194266 4194266
Anti-Troponin T (Cardiac Muscle), clone 9C2.1 -Q2640169 Q2640169
Anti-Troponin T (Cardiac Muscle), clone 9C2.1 Monoclonal Antibody 3097982