Millipore Sigma Vibrant Logo
Attention: We have moved. Merck Millipore products are no longer available for purchase on MerckMillipore.com.Learn More

ABE1024 Anti-Oligodendrocyte transcription factor 2 (OLIG2 Antibody)

This Anti-Oligodendrocyte transcription factor 2 (OLIG2 antibody is validated for use in WB, IH(P) for the detection of Oligodendrocyte transcription factor 2 (OLIG2.

MSDS (material safety data sheet) or SDS, CoA and CoQ, dossiers, brochures and other available documents.
Research Category: Neuroscience Research Sub-Category: Developmental Signaling Gene Symbol: Olig2 UniProt Number: Q9EQW6
ABE1024
100 µL  
Purchase on Sigma-Aldrich

Special Offers

Overview

Special Offers

100% Performance Guaranteed

Key Spec Table

Species ReactivityKey ApplicationsHostFormatAntibody Type
M, HWB, IH(P)GpSerumPolyclonal Antibody
Description
Catalogue NumberABE1024
DescriptionAnti-Oligodendrocyte transcription factor 2 (OLIG2 Antibody)
Alternate Names
  • Oligodendrocyte transcription factor 2
  • Oligo2
Background InformationOligodendrocyte transcription factor 2 (OLIG2), also known as Oligodendrocyte transcription factor 2 Oligo2, Class B basic helix-loop-helix protein 1 (bHLHb1), Class E basic helix-loop-helix protein 19 (bHLHe19), Protein kinase C-binding protein 2, Protein kinase C-binding protein RACK17, is encoded by the gene name OLIG2/ BHLHB1/ BHLHE19/ PRKCBP2/ RACK17. Olig2 is required for oligodendrocyte and motor neuron specification in the spinal cord, as well as for the development of somatic motor neurons in the hindbrain. It cooperates with OLIG1 to establish the pMN domain of the embryonic neural tube. Olig2 is an antagonist of V2 interneuron and of NKX2-2-induced V3 interneuron development. The restricted expression of Olig2 in oligodendrocytes makes AB9610 an excellent marker of oligodendroglia and oligodendrogliomas in development and mature systems. Olig2 is expressed in the brain and oligodendrocytes. Olig2 is strongly expressed in oligodendrogliomas, while expression is weak to moderate in astrocytomas. Expression in glioblastomas highly variable.
Product Information
FormatSerum
PresentationGuinea pig polyclonal serum with 0.05% sodium azide.
Quality LevelMQ100
Applications
ApplicationThis Anti-Oligodendrocyte transcription factor 2 (OLIG2 antibody is validated for use in WB, IH(P) for the detection of Oligodendrocyte transcription factor 2 (OLIG2.
Key Applications
  • Western Blotting
  • Immunohistochemistry (Paraffin)
Application NotesImmunohistochemistry Analysis: A 1:250 dilution from a representative lot detected Oligodendrocyte transcription factor 2 (OLIG2) in human cortical brain section tissue.
Biological Information
ImmunogenKLH-conjugated linear peptide corresponding to mouse Oligodendrocyte transcription factor 2 (OLIG2).
EpitopeUnknown
ConcentrationPlease refer to lot specific datasheet.
HostGuinea Pig
Species Reactivity
  • Mouse
  • Human
Antibody TypePolyclonal Antibody
Entrez Gene Number
Gene Symbol
  • Olig2
Purification MethodUnpurified
UniProt Number
Molecular Weight~37 kDa observed
Product Usage Statements
Quality AssuranceEvaluated by Western Blotting in mouse brain tissue lysate.

Western Blotting Analysis: A 1:1;000 dilution of this antibody detected Oligodendrocyte transcription factor 2 (OLIG2) in 10 µg of mouse brain tissue lysate.
Usage Statement
  • Unless otherwise stated in our catalog or other company documentation accompanying the product(s), our products are intended for research use only and are not to be used for any other purpose, which includes but is not limited to, unauthorized commercial uses, in vitro diagnostic uses, ex vivo or in vivo therapeutic uses or any type of consumption or application to humans or animals.
Storage and Shipping Information
Storage ConditionsStable for 1 year at -20°C from date of receipt.
Handling Recommendations: Upon receipt and prior to removing the cap, centrifuge the vial and gently mix the solution. Aliquot into microcentrifuge tubes and store at -20°C. Avoid repeated freeze/thaw cycles, which may damage IgG and affect product performance.
Packaging Information
Material Size100 µL
Global Trade Item Number
Catalogue Number GTIN
ABE1024 04055977121551