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MAB345A4 Anti-O4 Antibody, clone 81, Alexa Fluor®488 Conjugate

Anti-O4 Antibody, clone 81, Alexa Fluor®488 Conjugate detects level of O4 & has been published & validated for use in ICC.

MSDS (material safety data sheet) or SDS, CoA and CoQ, dossiers, brochures and other available documents.
Research Category: Neuroscience Research Sub-Category: Neurodegenerative Diseases
MAB345A4
100 µL  
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Key Spec Table

Species ReactivityKey ApplicationsHostFormatAntibody Type
R, M, H, Ch, BICCMAlexaFluor®488Monoclonal Antibody
Description
Catalogue NumberMAB345A4
DescriptionAnti-O4 Antibody, clone 81, Alexa Fluor®488 Conjugate
Background InformationOligodendrocytes and astrocytes are derived from common precursor cells, glioblasts (Sommer, 1981). O-Antigens are sulfatides, which function as differentiation markers on the surface of oligodendrocytes of the central nervous system. O4 is formed postnatally (Schachner, 1981) and is a marker for cell bodies and processes of oligodendrocytes types I and II (hairy eyeball type). During oligodendrocyte differentiation, O4 occurs in pro-oligodendrocytes, but not in O-2A-progenitor cells. O4 occurs from day 3 onwards in cell cultures of embryonic mouse brain. Anti-O4 can be used in myelination, demyelination and remyelination studies and in regeneration experiments.
References
Product Information
FormatAlexaFluor®488
Control
  • Undifferentiated rat oligodendrocyte precursor cells
PresentationPurified mouse monoclonal IgM conjugated to Alexa Fluor® 488 in PBS with 0.1% sodium azide and 15 mg/mL BSA.
Quality LevelMQ100
Applications
ApplicationAnti-O4 Antibody, clone 81, Alexa Fluor®488 Conjugate detects level of O4 & has been published & validated for use in ICC.
Key Applications
  • Immunocytochemistry
Biological Information
ImmunogenHomogenate of white matter of corpus callosum from bovine brain.
Clone81 (aka mAB 04)
HostMouse
SpecificityThis antibody recognizes Oligodendrocyte marker O4. Also reacts with certain galactolipids in sperm.
IsotypeIgM
Species Reactivity
  • Rat
  • Mouse
  • Human
  • Chicken
  • Bovine
Species Reactivity NoteDemonstrated to react with Rat. Predicted to react with Mouse, Human, Chicken, and Bovine based on 100% sequence homology.
Antibody TypeMonoclonal Antibody
Purification MethodPrecipitation followed by ion exchange purification
Physicochemical Information
Dimensions
Materials Information
Toxicological Information
Safety Information according to GHS
Safety Information
Product Usage Statements
Quality AssuranceEvaluated by Immunocytochemistry in undifferentiated rat oligodendrocyte precursor cells.

Immunocytochemistry Analysis: A 1:100 dilution of this antibody detected O4 in undifferentiated rat oligodendrocyte precursor cells.
Usage Statement
  • Unless otherwise stated in our catalog or other company documentation accompanying the product(s), our products are intended for research use only and are not to be used for any other purpose, which includes but is not limited to, unauthorized commercial uses, in vitro diagnostic uses, ex vivo or in vivo therapeutic uses or any type of consumption or application to humans or animals.
Storage and Shipping Information
Storage ConditionsMaintain refrigerated at 2-8 °C protected from light in undiluted aliquots for up to 6 months from date of receipt.
Packaging Information
Material Size100 µL
Transport Information
Supplemental Information
Specifications
Global Trade Item Number
Catalogue Number GTIN
MAB345A4 04053252688881

Documentation

Anti-O4 Antibody, clone 81, Alexa Fluor®488 Conjugate SDS

Title

Safety Data Sheet (SDS) 

Anti-O4 Antibody, clone 81, Alexa Fluor®488 Conjugate Certificates of Analysis

TitleLot Number
Anti-O4, clone 81, Alexa Fluor#174;488 Conjugate - 2141745 2141745
Anti-O4, clone 81, Alexa Fluor#174;488 Conjugate - 2031357 2031357
Anti-O4, clone 81, Alexa Fluor#174;488 Conjugate - 2234226 2234226
Anti-O4, clone 81, Alexa Fluor#174;488 Conjugate - Q1988591 Q1988591
Anti-O4, clone 81, Alexa Fluor®488 Conjugate 2970675
Anti-O4, clone 81, Alexa Fluor®488 Conjugate - 2383606 2383606
Anti-O4, clone 81, Alexa Fluor®488 Conjugate - 2318827 2318827
Anti-O4, clone 81, Alexa Fluor®488 Conjugate - 2887525 2887525
Anti-O4, clone 81, Alexa Fluor®488 Conjugate -2515522 2515522
Anti-O4, clone 81, Alexa Fluor®488 Conjugate -2581364 2581364
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