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ABN78C3 Anti-NeuN (rabbit) Antibody, Cy3 Conjugate

Anti-NeuN (rabbit) Antibody, Cy3 Conjugate is an antibody against NeuN (rabbit) for use in IC.

Anti-NeuN (rabbit) Antibody, Cy3 Conjugate MSDS (material safety data sheet) or SDS, CoA and CoQ, dossiers, brochures and other available documents.
Research Category: Neuroscience Research Sub-Category: Developmental Neuroscience Gene Symbol: NeuN
ABN78C3
100 µL  
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Key Spec Table

Species ReactivityKey ApplicationsHostFormatAntibody Type
R, MICCRbCy3Polyclonal Antibody
Description
Catalogue NumberABN78C3
DescriptionAnti-NeuN (rabbit) Antibody, Cy3 Conjugate
Alternate Names
  • NEUronal Nuclei
  • Neuronal Nuclei
Background InformationABN78 is a rabbit polyclonal version of the Anti-NeuN, clone A60 (MAB377), NeuN is a highly characterized and cited mouse monoclonal antibody that specifically recognizes the DNA-binding, neuron-specific protein NeuN, which is present in most CNS and PNS neuronal cell types of all vertebrates tested. NeuN protein distributions are apparently restricted to neuronal nuclei, perikarya and some proximal neuronal processes in both fetal and adult brain although, some neurons fail to be recognized by NeuN at all ages: INL retinal cells, Cajal-Retzius cells, Purkinje cells, inferior olivary and dentate nucleus neurons, and sympathetic ganglion cells are examples. Immunohistochemically detectable NeuN protein first appears at developmental timepoints that correspond with the withdrawal of the neuron from the cell cycle and/or with the initiation of terminal differentiation of the neuron. Immunoreactivity appears around E9.5 in the mouse neural tube and is extensive throughout the developing nervous system by E12.5. Strong nuclear staining suggests a nuclear regulatory protein function; however, no evidence currently exists as to whether the NeuN protein antigen has a function in the distal cytoplasm or whether it is merely synthesized there before being transported back into the nucleus. No difference between protein isolated from purified nuclei and whole brain extract on immunoblots has been found.
References
Product Information
FormatCy3
HS Code3002 15 90
Control
  • Rat E18 cortex cells
PresentationPurified rabbit polyclonal conjugated to Cy3 in PBS with 0.1% sodium azide and 15 mg/mL BSA.
Quality LevelMQ100
Applications
ApplicationAnti-NeuN (rabbit) Antibody, Cy3 Conjugate is an antibody against NeuN (rabbit) for use in IC.
Key Applications
  • Immunocytochemistry
Biological Information
ImmunogenGST-tagged recombinant protein corresponding to mouse NeuN.
EpitopeN-terminus
HostRabbit
SpecificityThis antibody recognizes NeuN at the N-terminus.
Species Reactivity
  • Rat
  • Mouse
Species Reactivity NoteDemonstrated to react with Mouse and Rat. The unconjugated rabbit Anti-NeuN (Catalog No. ABN78) has been shown to work in human.
Antibody TypePolyclonal Antibody
Gene Symbol
  • NeuN
Purification MethodAffinity Purfied
Molecular WeightThe unconjugated parent antibody (Cat. No. ABN78) has an observed molecular weight at ~46/48 kDa. An uncharacterized band appears at ~62 kDa in some lysates.
Physicochemical Information
Dimensions
Materials Information
Toxicological Information
Safety Information according to GHS
Safety Information
Product Usage Statements
Quality AssuranceEvaluated by Immunocytochemistry in rat E18 cortex cells.

Immunocytochemistry Analysis: A 1:100 dilution of this antibody detected NeuN in rat E18 cortex cells.
Usage Statement
  • Unless otherwise stated in our catalog or other company documentation accompanying the product(s), our products are intended for research use only and are not to be used for any other purpose, which includes but is not limited to, unauthorized commercial uses, in vitro diagnostic uses, ex vivo or in vivo therapeutic uses or any type of consumption or application to humans or animals.
Storage and Shipping Information
Storage ConditionsMaintain refrigerated at 2-8 °C protected from light in undiluted aliquots for up to 6 months from date of receipt.
Packaging Information
Material Size100 µL
Transport Information
Supplemental Information
Specifications
Global Trade Item Number
Catalogue Number GTIN
ABN78C3 04053252755392

Documentation

Anti-NeuN (rabbit) Antibody, Cy3 Conjugate SDS

Title

Safety Data Sheet (SDS) 

Anti-NeuN (rabbit) Antibody, Cy3 Conjugate Certificates of Analysis

TitleLot Number
Anti-NeuN (rabbit polyclonal), Cy3 -2718271 2718271
Anti-NeuN (rabbit polyclonal), Cy3 -2750097 2750097
Anti-NeuN (rabbit polyclonal), Cy3 Conjugate 2982381
Anti-NeuN (rabbit polyclonal), Cy3 Conjugate 3075602
Anti-NeuN (rabbit polyclonal), Cy3 Conjugate 2901575
Anti-NeuN (rabbit polyclonal), Cy3 Conjugate 3109759
Anti-NeuN (rabbit polyclonal), Cy3 Conjugate 3559034
Anti-NeuN (rabbit polyclonal), Cy3 Conjugate - 2128239 2128239
Anti-NeuN (rabbit polyclonal), Cy3 Conjugate - 2388361 2388361
Anti-NeuN (rabbit polyclonal), Cy3 Conjugate - 2461588 2461588
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