Millipore Sigma Vibrant Logo
Attention: We have moved. Merck Millipore products are no longer available for purchase on MerckMillipore.com.Learn More

AB5400 Anti-GFR α3 Antibody

This Anti-GFR α3 Antibody is validated for use in WB, IH for the detection of GFR α3.

Anti-GFR α3 Antibody MSDS (material safety data sheet) or SDS, CoA and CoQ, dossiers, brochures and other available documents.
Research Category: Neuroscience Research Sub-Category: Neurochemistry & Neurotrophins Gene Symbol: GFRA3, ORFNames=UNQ339/PRO538/PRO3664, GFR-alpha-3, GFRa-3 UniProt Number: O60609
AB5400
50 µL  
Purchase on Sigma-Aldrich

Special Offers

Overview

Replacement Information

Special Offers

100% Performance Guaranteed

Key Spec Table

Species ReactivityKey ApplicationsHostFormatAntibody Type
MWB, IHCRbSerumPolyclonal Antibody
Description
Catalogue NumberAB5400
Brand Family Chemicon®
Trade Name
  • Chemicon
DescriptionAnti-GFR α3 Antibody
References
Product Information
FormatSerum
PresentationRabbit serum. Lyophilized. Contains no preservative. Reconstitute with 50 μL of sterile distilled water. Centrifuge if necessary to remove any residue.
Quality LevelMQ100
Applications
ApplicationThis Anti-GFR α3 Antibody is validated for use in WB, IH for the detection of GFR α3.
Key Applications
  • Western Blotting
  • Immunohistochemistry
Application NotesWestern blot: 1:500

Immunohistochemistry: 1:500-1:1,000

Optimal working dilutions must be determined by end user.
Biological Information
ImmunogenAn eleven amino acid peptide corresponding to the N-terminus of the mouse GFR(3 protein.
HostRabbit
SpecificityGFRa3. No reactivity with its homologues.
Species Reactivity
  • Mouse
Antibody TypePolyclonal Antibody
Entrez Gene Number
Entrez Gene SummaryThe protein encoded by this gene is a glycosylphosphatidylinositol(GPI)-linked cell surface receptor and a member of the GDNF receptor family. It forms a signaling receptor complex with RET tyrosine kinase receptor and binds the ligand, artemin.
Gene Symbol
  • GFRA3
  • ORFNames=UNQ339/PRO538/PRO3664
  • GFR-alpha-3
  • GFRa-3
UniProt Number
UniProt SummaryFUNCTION: SwissProt: O60609 # Receptor for the glial cell line-derived neurotrophic factor, ARTN (artemin). Mediates the artemin-induced autophosphorylation and activation of the RET receptor tyrosine kinase.
SIZE: 400 amino acids; 44511 Da
SUBCELLULAR LOCATION: Cell membrane; Lipid-anchor, GPI-anchor.
TISSUE SPECIFICITY: Widely expressed in adult and fetus which exhibit a similar pattern. Essentially not expressed in the central nervous system, but highly expressed in several sensory and sympathetic ganglia of the peripheral nervous system. Moderate expression in many non-neuronal tissues, particularly those of the digestive and urogenital systems, but high expression in stomach and appendix. Several types of glandular tissues show low expression. Very low or no expression detected in the hematopoietic system.
PTM: N-glycosylated.
SIMILARITY: SwissProt: O60609 ## Belongs to the GDNFR family.
Physicochemical Information
Dimensions
Materials Information
Toxicological Information
Safety Information according to GHS
Safety Information
Product Usage Statements
Usage Statement
  • Unless otherwise stated in our catalog or other company documentation accompanying the product(s), our products are intended for research use only and are not to be used for any other purpose, which includes but is not limited to, unauthorized commercial uses, in vitro diagnostic uses, ex vivo or in vivo therapeutic uses or any type of consumption or application to humans or animals.
Storage and Shipping Information
Storage ConditionsMaintain lyophilized material at -20°C to -70°C for up to 6 months after date of receipt. After reconstitution maintain frozen at -20°C in undiluted aliquots for up to 6 months. Avoid repeated freeze/thaw cycles.
Packaging Information
Material Size50 µL
Transport Information
Supplemental Information
Specifications
Global Trade Item Number
Catalogue Number GTIN
AB5400 04053252361623