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ABS1065 Anti-CES2 Antibody

This Anti-CES2 Antibody is validated for use in Western Blotting, Immunohistochemistry for the detection of CES2 .

Anti-CES2 Antibody MSDS (material safety data sheet) or SDS, CoA and CoQ, dossiers, brochures and other available documents.
Research Category: Signaling Research Sub-Category: Developmental Signaling Gene Symbol: CES2, ICE UniProt Number: O00748
ABS1065
100 µL  
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Key Spec Table

Species ReactivityKey ApplicationsHostFormatAntibody Type
H, M, RWB, IHCRbSerumPolyclonal Antibody
Description
Catalogue NumberABS1065
DescriptionAnti-CES2 Antibody
Alternate Names
  • Cocaine esterase
  • CES2
  • Carboxylesterase 2
  • hCE-2
  • CE-2
  • Methylumbelliferyl-acetate deacetylase 2
Background InformationCocaine esterase (EC 3.1.1.1; EC 3.1.1.56; EC 3.1.1.84; UniProt O00748; also known as Carboxylesterase 2, CE-2, hCE-2, iCE, Intestinal carboxylesterase, Liver carboxylesterase-2, Methylumbelliferyl-acetate deacetylase 2) is encoded by the CES2 (also known as CES2A1, ICE) gene (Gene ID 8824) in human. Human carboxylesterase 1 (CES1 or CES1A) and carboxylesterase 2 (CES2) are serine esterases responsible for the hydrolysis of ester and amide bonds present in several types of chemical compounds, including prodrugs such as imidapril and irinotecan (CPT-11). CES1A and CES2 are the two major members among human CES genes. CES1 is predominantly expressed in the liver and the lung, whereas CES2 is expressed in the gastrointestinal tract and the liver.
References
Product Information
FormatSerum
PresentationRabbit polyclonal antibody in serum with 0.05% sodium azide.
Quality LevelMQ100
Applications
ApplicationThis Anti-CES2 Antibody is validated for use in Western Blotting, Immunohistochemistry for the detection of CES2 .
Key Applications
  • Western Blotting
  • Immunohistochemistry
Application NotesImmunohistochemistry Analysis: A 1:1,000 dilution from a representative lot detected CES2 in rat liver and human liver tissue.
Biological Information
ImmunogenLinear peptide corresponding to the C-terminus of human CES2.
EpitopeC-terminus
ConcentrationPlease refer to lot specific datasheet.
HostRabbit
SpecificityExpected to react with both spliced isoforms.
Species Reactivity
  • Human
  • Mouse
  • Rat
Species Reactivity NoteHuman, Mouse, Rat. Predicted to react with Non-Human Primate based on 100% sequence homology.
Antibody TypePolyclonal Antibody
Entrez Gene Number
Gene Symbol
  • CES2
  • ICE
Purification MethodUnpurified
UniProt Number
Molecular Weight~58 kDa observed
Physicochemical Information
Dimensions
Materials Information
Toxicological Information
Safety Information according to GHS
Safety Information
Product Usage Statements
Quality AssuranceEvaluated by Western Blotting in mouse liver tissue lysate.

Western Blotting Analysis: A 1:500 dilution of this antibody detected CES2 in 10 µg of mouse liver tissue lysate.
Usage Statement
  • Unless otherwise stated in our catalog or other company documentation accompanying the product(s), our products are intended for research use only and are not to be used for any other purpose, which includes but is not limited to, unauthorized commercial uses, in vitro diagnostic uses, ex vivo or in vivo therapeutic uses or any type of consumption or application to humans or animals.
Storage and Shipping Information
Storage ConditionsStable for 1 year at -20°C from date of receipt.
Handling Recommendations: Upon receipt and prior to removing the cap, centrifuge the vial and gently mix the solution. Aliquot into microcentrifuge tubes and store at -20°C. Avoid repeated freeze/thaw cycles, which may damage IgG and affect product performance.
Packaging Information
Material Size100 µL
Transport Information
Supplemental Information
Specifications
Global Trade Item Number
Catalogue Number GTIN
ABS1065 04055977298109