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475956 c-Myc Inhibitor - CAS 403811-55-2 - Calbiochem

Overview

Key Spec Table

CAS #Empirical Formula
403811-55-2C₁₂H₁₁NOS₂

Pricing & Availability

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475956-10MG
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      Description
      OverviewA cell-permeable thiazolidinone compound that specifically inhibits the c-Myc-Max interaction, thereby preventing the transactivation of c-Myc target gene expression. Shown to inhibit tumor cell growth in a c-Myc-dependent manner both in vitro and in vivo (64 μM using c-Myc transfected Rat1a fibroblasts).
      Catalogue Number475956
      Brand Family Calbiochem®
      Synonyms10058-F4, (Z,E)-5-(4-Ethylbenzylidine)-2-thioxothiazolidin-4-one
      References
      ReferencesYin, X., et al. 2003. Oncogene 22, 6151.
      Product Information
      CAS number403811-55-2
      ATP CompetitiveN
      DeclarationSold under license of U.S. Patent 7,026,343.
      FormYellow solid
      Hill FormulaC₁₂H₁₁NOS₂
      Chemical formulaC₁₂H₁₁NOS₂
      ReversibleN
      Structure formula ImageStructure formula Image
      Quality LevelMQ100
      Biological Information
      Primary Targetc-Myc
      Purity≥95% by HPLC (sum of two isomers)
      Physicochemical Information
      Cell permeableY
      Storage and Shipping Information
      Ship Code Ambient Temperature Only
      Toxicity Carcinogenic / Teratogenic
      Storage +2°C to +8°C
      Protect from Light Protect from light
      Do not freeze Ok to freeze
      Special InstructionsFollowing reconstitution, aliquot and freeze (-20°C). Stock solutions are stable for up to 3 months at -20°C.
      Packaging Information
      Packaged under inert gas Packaged under inert gas
      Global Trade Item Number
      Catalogue Number GTIN
      475956-10MG 04055977184303