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612080 TIMP-1, Human Neutrophil Granulocyte - Calbiochem

Native TIMP-1 from human granulocyte.

MSDS (material safety data sheet) or SDS, CoA and CoQ, dossiers, brochures and other available documents.

Synonyms: Tissue Inhibitor of Metalloproteinase-1

Primary Target: MMP activity
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612080
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Overview

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612080-5UG
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      		 Plastic ampoule 5 μg
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      Description
      OverviewNative TIMP-1 from human granulocyte. Member of a family of inhibitors that participate in the activation and regulation of MMP activity. Forms a non-covalent stoichiometric complex with latent and active MMPs. Binds to pro-MMP-9 and MMP-9 via their C-terminal domains.
      Catalogue Number612080
      Brand Family Calbiochem®
      SynonymsTissue Inhibitor of Metalloproteinase-1
      References
      ReferencesKolkenbrock, H., et al. 1996. Biol. Chem. 377, 529.
      Kolkenbrock, H., et al. 1995. Biol. Chem. Hoppe Seyler 376, 495.
      Product Information
      ATP CompetitiveN
      FormLiquid
      FormulationIn 200 mM NaCl, 50 mM Tris-HCl, 5 mM CaCl₂, 1 µM ZnCl₂, 0.05% BRIJ® 35 Detergent, 0.05% NaN₃, pH 7.0.
      ReversibleN
      Quality LevelMQ100
      Applications
      Biological Information
      Primary TargetMMP activity
      Purity≥90% by SDS-PAGE
      SourcePrepared from stimulated neutrophils that have been shown by certified tests to be negative for HBsAg and for antibodies to HIV and HCV.
      Concentration Label Please refer to vial label for lot-specific concentration
      Physicochemical Information
      Cell permeableN
      Dimensions
      Materials Information
      Toxicological Information
      Safety Information according to GHS
      Safety Information
      Product Usage Statements
      Storage and Shipping Information
      Ship Code Dry Ice Only
      Toxicity Standard Handling
      Storage ≤ -70°C
      Avoid freeze/thaw Avoid freeze/thaw
      Do not freeze Ok to freeze
      Special InstructionsFollowing initial thaw, aliquot and freeze (-70°C).
      Packaging Information
      Transport Information
      Supplemental Information
      Specifications
      Global Trade Item Number
      Catalogue Number GTIN
      612080-5UG 04055977187700

      Documentation

      TIMP-1, Human Neutrophil Granulocyte - Calbiochem SDS

      Title

      Safety Data Sheet (SDS) 

      TIMP-1, Human Neutrophil Granulocyte - Calbiochem Certificates of Analysis

      TitleLot Number
      612080

      References

      Reference overview
      Kolkenbrock, H., et al. 1996. Biol. Chem. 377, 529.
      Kolkenbrock, H., et al. 1995. Biol. Chem. Hoppe Seyler 376, 495.
      Data Sheet

      Note that this data sheet is not lot-specific and is representative of the current specifications for this product. Please consult the vial label and the certificate of analysis for information on specific lots. Also note that shipping conditions may differ from storage conditions.

      Revision23-March-2009 JSW
      SynonymsTissue Inhibitor of Metalloproteinase-1
      DescriptionNative TIMP-1 from human granulocyte. Member of a family of inhibitors that participate in the activation and regulation of MMP activity. Forms a non-covalent stochiometric complex with latent and active MMPs. Binds to pro-MMP-9 and MMP-9 via their C-terminal domains.
      FormLiquid
      FormulationIn 200 mM NaCl, 50 mM Tris-HCl, 5 mM CaCl₂, 1 µM ZnCl₂, 0.05% BRIJ® 35 Detergent, 0.05% NaN₃, pH 7.0.
      Concentration Label Please refer to vial label for lot-specific concentration
      SourcePrepared from stimulated neutrophils that have been shown by certified tests to be negative for HBsAg and for antibodies to HIV and HCV.
      Purity≥90% by SDS-PAGE
      Storage Avoid freeze/thaw
      ≤ -70°C
      Do Not Freeze Ok to freeze
      Special InstructionsFollowing initial thaw, aliquot and freeze (-70°C).
      Toxicity Standard Handling
      ReferencesKolkenbrock, H., et al. 1996. Biol. Chem. 377, 529.
      Kolkenbrock, H., et al. 1995. Biol. Chem. Hoppe Seyler 376, 495.