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FCMAB207F Milli-Mark™ Anti-CD71-FITC Antibody, clone Ber-T9

Detect CD71 using this Milli-Mark Anti-CD71-FITC Antibody, clone Ber-T9 validated for use in FC.

MSDS (material safety data sheet) or SDS, CoA and CoQ, dossiers, brochures and other available documents.
Research Category: Inflammation & Immunology Research Sub-Category: Immunoglobulins & Immunology UniProt Number: P02786
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FCMAB207F
100 tests  
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      Overview

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      Key Spec Table

      Species ReactivityKey ApplicationsHostFormatAntibody Type
      HFCMFITCMonoclonal Antibody
      Description
      Catalogue NumberFCMAB207F
      Trade Name
      • Milli-Mark
      DescriptionMilli-Mark™ Anti-CD71-FITC Antibody, clone Ber-T9
      Alternate Names
      • Transferrin receptor protein 1
      • TfR1
      • TfR
      • T9
      • p90
      Background InformationCD71 is a 190 kDa disulfide-bonded homodimeric type II transmembrane glycoprotein. CD71 is the receptor for transferrin. CD71 is involved in iron (Fe3+) uptake, and expression is regulated by the metabolic demand for iron, which is essential for the growing cell (Goding, 2002). CD71 is more abundantly expressed in rapidly dividing cells than quiescent cells (Newman, 1982; Sutherland, 1981). In normal tissues, high expression of CD71 is seen in the placental trophoblast and hemoglobin-synthesizing reticulocytes (Newman, 1982) but expression is lost in mature erythrocytes (Sutherland, 1981). Anti-CD71, Ber-79, was included in the Fifth International Workshop and Conference on Human Leucocyte Differentiation Antigens, and studies by a number of laboratories confirmed its reactivity with CD71 (Boeker, 1995).
      References
      Product Information
      FormatFITC
      HS Code3002 15 90
      Control
      • Human Lymphocytes
      PresentationPurified Mouse monoclonal IgG1 conjugated to FITC in 0.05M Tris-HCl buffer with 1% BSA, Sodium Azide at 0.097% at pH 7.2.
      Quality LevelMQ100
      Applications
      ApplicationDetect CD71 using this Milli-Mark Anti-CD71-FITC Antibody, clone Ber-T9 validated for use in FC.
      Key Applications
      • Flow Cytometry
      Biological Information
      CloneBer-T9
      HostMouse
      SpecificityAntibody recognizes Human CD71 antigen.
      IsotypeIgG1κ
      Species Reactivity
      • Human
      Antibody TypeMonoclonal Antibody
      Entrez Gene Number
      Purification MethodProtein A Purfied
      UniProt Number
      UniProt SummaryCellular uptake of iron occurs via receptor-mediated endocytosis of ligand-occupied transferrin receptor into specialized endosomes. Endosomal acidification leads to iron release. The apotransferrin-receptor complex is then recycled to the cell surface with a return to neutral pH and the concomitant loss of affinity of apotransferrin for its receptor. Transferrin receptor is necessary for development of erythrocytes and the nervous system By similarity. A second ligand, the heditary hemochromatosis protein HFE, competes for binding with transferrin for an overlapping C-terminal binding site.
      Molecular Weight 190 kDa (Goding, 2002)
      Physicochemical Information
      Dimensions
      Materials Information
      Toxicological Information
      Safety Information according to GHS
      Safety Information
      Product Usage Statements
      Quality AssuranceEvaluated by flow cytometry using human lymphocytes
      Usage Statement
      • Unless otherwise stated in our catalog or other company documentation accompanying the product(s), our products are intended for research use only and are not to be used for any other purpose, which includes but is not limited to, unauthorized commercial uses, in vitro diagnostic uses, ex vivo or in vivo therapeutic uses or any type of consumption or application to humans or animals.
      Storage and Shipping Information
      Storage ConditionsMaintain refrigerated at 2-8°C protected from light in undiluted aliquots for up to 6 months from date of receipt.
      Packaging Information
      Material Size100 tests
      Transport Information
      Supplemental Information
      Specifications
      Global Trade Item Number
      Catalogue Number GTIN
      FCMAB207F 04053252375477

      Documentation

      Milli-Mark™ Anti-CD71-FITC Antibody, clone Ber-T9 SDS

      Title

      Safety Data Sheet (SDS) 

      Milli-Mark™ Anti-CD71-FITC Antibody, clone Ber-T9 Certificates of Analysis

      TitleLot Number
      Milli-Mark Anti-CD71-FITC, clone Ber-T9 - 2119012 2119012
      Milli-Mark Anti-CD71-FITC, clone Ber-T9 - 1991860 1991860
      Milli-Mark Anti-CD71-FITC, clone Ber-T9 - NG1947167 NG1947167
      Milli-Mark Anti-CD71-FITC, clone Ber-T9 - NRG1775602 NRG1775602
      Milli-Mark™ Anti-CD71-FITC, -2629035 2629035
      Milli-Mark™ Anti-CD71-FITC, clone Ber-T9 - 2495476 2495476
      Milli-Mark™ Anti-CD71-FITC, clone Ber-T9 - 2514246 2514246
      Milli-Mark™ Anti-CD71-FITC, clone Ber-T9 - 3148522 3148522
      Milli-Mark™ Anti-CD71-FITC, clone Ber-T9 - 3749967 3749967
      Milli-Mark™ Anti-CD71-FITC, clone Ber-T9 - 3958864 3958864
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      Categories

      Life Science Research > Antibodies and Assays > Primary Antibodies